Results 101 to 110 of about 203,683 (192)

Phospholipid Interconversion and Transport Are Altered in Glaucoma

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Decreased phosphatidylserine (PS) and increased phosphatidylethanolamine (PE) occur in both trabecular meshwork (TM) cells and aqueous humor due to aberrant phosphatidylserine decarboxylase (PSD) over‐expression, and variation in levels of individual PS or PE species differing by only a few acyl chains occurs due to impaired lipid transport due to ...
Genea Edwards, Ruminder Kaur, Anna Mueller, Noël Ziebarth, Richard K. Lee, Sanjoy K. Bhattacharya   +5 more
wiley   +1 more source

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

Advanced Science, Volume 13, Issue 3, 14 January 2026.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu, Bixiao Liu, Yu Yang, Tao Meng, Yuanyuan Chang, Yao Peng, Jia Guo, Zhuqing Wang, Hongqian Guo, Liuhua Zhou, Xiaozhi Zhao   +10 more
wiley   +1 more source

Corneal densitometry after photorefractive keratectomy, laser-assisted in situ keratomileusis, and small-incision lenticule extraction [PDF]

, 2017
Received: 29 September 2016 ; Accepted in revised form: 27 April 2017Purpose: The aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three ...
López, Alfredo, Jáñez, Oscar, I Illarramendi, Garzón Jiménez, Nuria, P Caro, A López, Mendicute, Javier, Caro, Pedro, F Poyales, J Mendicute, N Garzón, F Argüeso, O Jáñez, Poyales Galán, Francisco, Illarramendi, Igor, Argüeso Díaz-Trechuelo, Francisco   +15 more
core   +2 more sources

Selective knockout of murine glutamic acid‐rich protein 2 significantly alters dark continuous noise in rod photoreceptors

The Journal of Physiology, Volume 604, Issue 1, Page 460-478, 1 January 2026.
Abstract figure legend GARP2 has a minor role in maintaining the structural integrity of the rod outer segments as a function of age, but an important role in regulating rod photoreceptor continuous noise, likely through stabilization of PDE6 basal activity.
Delores A. Stacks, Ulisse Bocchero, Marci L. DeRamus, Mai N. Nguyen, Jeffrey Messinger, Timothy W. Kraft, Steven J. Pittler, Johan Pahlberg   +7 more
wiley   +1 more source

Buyang Huanwu Decoction Alleviates Chronic Intermittent Hypoxia–Induced Myocardial Inflammation and Fibrosis via the NF‐κB/LOX Signaling Pathway

Human Mutation, Volume 2026, Issue 1, 2026.
Objective To investigate the protective effects of Buyang Huanwu decoction (BYHW) on myocardial injury induced by chronic intermittent hypoxia (CIH) in rats and to analyze its potential regulatory mechanism through the NF‐κB/LOX signaling pathway. Methods Then, 36 adult male Sprague–Dawley (SD) rats (weighing 200–250 g) were randomly divided into six ...
Lijun Ou, Chenyi Liu, Weicheng Zhao, Cairu Liu, Ye Ning, Minghua Ren   +5 more
wiley   +1 more source

Comparative Topographic and Tomographic Assessment of Post‐LASIK Corneal Ectasia

Journal of Ophthalmology, Volume 2026, Issue 1, 2026.
Purpose To evaluate and compare the topographic and tomographic characteristics of post–laser in situ keratomileusis (LASIK) ectasia (PLE) with keratoconus (KC) and normal control eyes using the Sirius imaging system. Methods This comparative cross‐sectional study included eyes with KC, PLE ectasia, and normal control eyes.
Abdelrahman Salman, Yasar Sakarya
wiley   +1 more source

Topometric Indices And Corneal Densitometry Change After Corneal Refractive Surgery Combined With Simultaneous Collagen Crosslinking

Clinical Ophthalmology, 2019
Yonrawee Piyacomn, Ngamjit Kasetsuwan, Vilavun Puangsricharern, Usanee Reinprayoon, Vannarut Satitpitakul, Patchima Chantaren Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok ...
Piyacomn Y, Kasetsuwan N, Puangsricharern V, Reinprayoon U, Satitpitakul V, Chantaren P   +5 more
doaj  

Corneal densitometry to assess the corneal cysteine deposits in patients with cystinosis [PDF]

Aims: To assess the suitability of corneal densitometry measurements obtained with Scheimpflug imaging in estimating the corneal changes caused by cystine deposits in the cornea in patients with cystinosis.Methods: Scheimpflug imaging (Pentacam) was ...
Radhakrishnan, Hema; id_orcid, Alzahrani, Khaled, Biswas, Susmito   +2 more
core   +2 more sources

PIK3C2A‐Related Clinical Phenotype and Cellular Charaterization Linked to Functional SHH Primary Cilia Defect

Clinical Genetics, Volume 108, Issue 6, Page 696-707, December 2025.
Trio exome sequencing allowed the identification of two novel compound heterozygous variants in PIK3C2A, defining the fifth family presenting a PIK3C2A‐related syndrome characterized by pulverulent cataracts and deafness. Functional testing revealed impaired PI metabolism and primary dysfunction phenotype.
Adella Karam, Clarisse Delvallée, Bénédicte Gérard, Elodie Javey, Pascal Kessler, Valérie Pelletier, Jean‐Baptiste Lamouche, Nicolas Le May, Jean Muller, Hélène Dollfus   +9 more
wiley   +1 more source

Collagen XII Plays a More Prominent Cell‐Mediated Role in Tendon Organization Compared to Matrix Assembly During Postnatal Development

The FASEB Journal, Volume 39, Issue 21, 15 November 2025.
Temporal roles of collagen XII in regulating cell and matrix organization during tendon development were investigated by tendon‐targeted knockout throughout development and induced knockdown at birth. Tendon‐targeted knockout disrupted patellar tendon morphology, cell and matrix organization, and mechanical properties.
Ashley K. Fung, Stephanie N. Weiss, Courtney A. Nuss, William Yen, Susan W. Volk, Nathaniel A. Dyment, Louis J. Soslowsky   +6 more
wiley   +1 more source