Results 101 to 110 of about 5,991 (200)

Subconjunctival Injection of XG-102, a c-Jun N-Terminal Kinase Inhibitor Peptide, in the Treatment of Endotoxin-Induced Uveitis in Rats. [PDF]

, 2015
Purpose: XG-102, a TAT-coupled dextrogyre peptide inhibiting the c-Jun N-terminal kinase, was shown efficient in the treatment of experimental uveitis. Preclinical studies are now performed to determine optimal XG-102 dose and route of administration in ...
Abadie, C., Behar-Cohen, F., Berdugo, M., Combette, J.M., Deloche, C., El Zaoui, I., Kowalczuk, L., Naud, M.C., Touchard, E., Zhao, M.   +9 more
core   +2 more sources

Echinacea purpurea polysaccharide reduces the latency rate in herpes simplex virus type-1 infections

, 2009
Objective: During the latency period of herpes simplex virus type-1 (HSV-1), the virus can occasionally reactivate, travel back to the eye and cause recurrent ocular disease.
Arefian, E., Ghaemi, A., Gill, P., Hassan, Z., Soleimanjahi, H., Soudi, S.   +5 more
core   +1 more source

Corneal light scattering and anterior segment findings in rheumatoid arthritis patients: a prospective study on disease monitoring [PDF]

International Journal of Ophthalmology
AIM: To evaluate changes in corneal light scattering and anterior segment parameters in newly diagnosed rheumatoid arthritis (RA) patients who achieved remission with systemic treatment, compared to healthy controls.
Serife Ciloglu Hayat, Yusuf Cem Yilmaz, Sefik Can Ipek, Handan Yarkan   +3 more
doaj   +1 more source

Inhibition of cyclin-dependent kinase 7 down-regulates yes-associated protein expression in mesothelioma cells. [PDF]

, 2020
Cyclin-dependent kinase 7 (CDK7) is a protein kinase that plays a major role in transcription initiation. Yes-associated protein (YAP) is a main effector of the Hippo/YAP signalling pathway.
Bin, Hu, Chan, Geraldine, Jablons, David M, Kyoyama, Hiroyuki, Li, Hui, Liu, Luwei, Liu, Shu, Miao, Jinbai, Urisman, Anatoly, Wang, Yucheng, Xu, Zhidong, Yang, Yi-Lin, You, Liang   +12 more
core  

P27 Expression in Endothelin-1 Stimulated Mitogenesis [PDF]

, 2007
Bovine corneal endothelial cells (BCECs) have been shown in our lab to synthesize and secrete endothelin-1 (ET-1). The endothelin-1 binds ETA receptors, this elevates intracellular calcium, stimulate DNA replication and cell division.
Kiriu, Joseph
core   +1 more source

Short-term effects of microstructured surfaces: role in cell differentiation toward a contractile phenotype [PDF]

, 2015
Cell adhesion plays a key role in cell behavior, in terms of migration, proliferation, differentiation and apoptosis. All of these events concur with tissue regeneration and remodeling mechanisms, integrating a complex network of intracellular signaling ...
Ana Marina Ferreira, Francesca Boccafoschi, Mario Cannas, Martina Ramella, RASPONI, MARCO, VESENTINI, SIMONE   +5 more
core   +1 more source

Corneal densitometry changes in keratoconus patients after intrastromal corneal ring segments implantation

Journal of the Egyptian Ophthalmological Society
Background Keratoconus (KC) is an ectatic corneal disorder characterized by progressive corneal thinning with myopic astigmatism. Intrastromal corneal ring segments (ICRS) have been broadly selected as a surgical intervention for KC correction to delay ...
Ahmed I Basiony, Mohammad M. E Mohammad Abdulfattah, Asmaa M Ibrahim   +2 more
doaj   +1 more source

Repeatability of Corneal Elevation Maps in Keratoconus Patients Using the Tomography Matching Method [PDF]

, 2017
To assess repeatability of corneal tomography in successive measurements by Pentacam in keratoconus (KC) and normal eyes based on the Iterative Closest Point (ICP) algorithm. The study involved 143 keratoconic and 143 matched normal eyes.
Bao, FJ, Chen, SH, Elsheikh, A, Geraghty, B, Huang, LF, Huang, W, Wang, JJ, Wang, QM, Zhao, YP, Zheng, XB, Zheng, YR   +10 more
core   +2 more sources

Corneal and lens densitometry evaluation with Pentacam HR in children and adolescents with beta thalassemia major: a case–control study

Egyptian Pediatric Association Gazette
Background Beta thalassemia major is an inherited blood disorder due to a mutation of the β globin chain gene. Ocular complications have increasingly been reported in β-thalassemia patients with a negative influence on the health related quality of life.
Diana Hanna, Mervat Atfy, Ashraf Bor’i, Marwa Elsayed, Eman Mohamed Abd el-Sattar, Dalia Gameil   +5 more
doaj   +1 more source

Corneal stromal changes following simple limbal epithelial transplantation on Scheimpflug densitometry: Early results

Indian Journal of Ophthalmology
Context: Chemical injury to eyes causes limbal stem cell deficiency (LSCD), which leads to conjunctival epithelium and underlying stromal changes. Simple limbal epithelial transplant helps to restore corneal epithelium and corneal stromal clarity.
Mayur Jain, Nidhi Gupta, Monica Lohchab, Abha Gour, Virender S Sangwan, Bhupesh Singh   +5 more
doaj   +1 more source