Results 81 to 90 of about 203,683 (192)

Protein kinase Cδ and pharmacomechanical coupling: Re‐envisioning cerebral vascular control

The Journal of Physiology, EarlyView.
Abstract figure legend Top, G‐protein coupled receptors trigger electromechanical and pharmacomechanical coupling, the latter via signal transduction pathways that inhibit myosin light chain phosphatase. Middle, the relative contribution of electromechanical and pharmacomechanical coupling varies with the concentration and the vessel area to which ...
Nadia Haghbin, Michelle S. M. Kim, Mohammed El‐lakany, David M. Richter, Dabasish Kumar Saha, Galina Yu. Mironova, David A. Steven, Jonathan C. Lau, Mel Boulton, Nikolaos M. Tsoukias, Donald G. Welsh   +10 more
wiley   +1 more source

Corneal imaging and densitometry measurements to monitor fuchs progression and treatments outcomes [PDF]

, 2016
PurposeFuchs’ dystrophy is a degenerative disease of the corneal endothelium leading to corneal edema and eventually to loss of vision. There are several treatment options including corneal transplantation, which can be full (Penetrating Keratoplasty) or
Brahma, Arun, Morley, Debbie, Alzahrani, Khaled, Hillarby, M Chantal, Carley, Fiona   +4 more
core   +1 more source

Inverstigation of corneal and lens densitometry in eyes ofpatients with primary myelofibrosis [PDF]

, 2021
Aim: To investigate the corneal-lens densitometry and endothelial cells of Primary myelofibrosis patients. Materials and Methods: We evaluated 49 eyes of 49 primary myelofibrosis patients on follow up in hematology clinic and comparedto 46 eyes of 46 age
Akbay, Burak, Yilmaz, Ugur, Akgün Çağlıyan, Gülsüm   +2 more
core   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

Age-Related Corneal Transparency Changes Evaluated With an Alternative Method to Corneal Densitometry

Cornea, 2020
Purpose: To compare densitometry distribution analysis (DDA), a platform-independent method to assess corneal transparency, with traditional corneal densitometry. Methods: A total of 196 healthy participants aged 43.3 ± 18.0 years (range 18–79 years) were recruited for assessment ...
Consejo, Alejandra, Jiménez-García, Marta, Rozema, Jos J.   +2 more
openaire   +4 more sources

Changes in the mean corneal densitometry values in eyes with various fitting modes at different time points. [PDF]

, 2022
Changes in the mean corneal densitometry values in eyes with various fitting modes at different time points.
Lili Jing (254220), Lianghui Zhao (11539166), Jie Li (15030), Xianli Du (6280370)   +3 more
core   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, Volume 59, Issue 7, July 2026.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

Loss of Corneal Nerves and Corneal Haze in Patients with Fuchs’ Endothelial Corneal Dystrophy with the Transcription Factor 4 Gene Trinucleotide Repeat Expansion

Ophthalmology Science, 2023
Objective: Seventy percent of Fuchs’ endothelial corneal dystrophy (FECD) cases are caused by an intronic trinucleotide repeat expansion in the transcription factor 4 gene (TCF4). The objective of this study was to characterize the corneal subbasal nerve
Matthew Gillings, MD, Andrew Mastro, MD, Xunzhi Zhang, Kelly Kiser, MD, Jane Gu, Chao Xing, PhD, Danielle M. Robertson, OD, PhD, W. Matthew Petroll, PhD, V. Vinod Mootha, MD   +8 more
doaj   +1 more source

Polygonati Rhizoma Attenuates Oxidative Stress‐Induced Senescence in Periodontal Ligament Stem Cells

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Network pharmacology identified the potential targets and pathways of Polygonati Rhizoma (PR) against aging‐related periodontitis through PPI, GO/KEGG enrichment, and molecular docking. Experimental validation in a D‐galactose‐induced senescence model of periodontal ligament stem cells showed that PR‐medicated serum attenuated cellular senescence and ...
Xinran Feng, Ying An, Fanfan Hou, Qian Guo, Shanshan Cai, Hongbin Xu, Youfu He   +6 more
wiley   +1 more source

Corneal Stromal Densitometry Evolution in a Clinical Model of Cellular Therapy for Advanced Keratoconus [PDF]

, 2022
20.500.12530/87908The aim of this study was to report the corneal densitometry (CD) evolution studied by Scheimpflug tomography, anterior segment optical coherence tomography (AS-OCT), and confocal microscopy changes, in patients with advanced ...
El Zarif, Mona, Jorge L. Alió, Alió Del Barrio, Jorge L, Karim A Jawad, Mingo, David, Jorge L. Alió del Barrio, David Mingo, A Jawad, Karim, Alió, Jorge L, Mona El Zarif   +9 more
core   +1 more source