Results 81 to 90 of about 5,991 (200)

Phospholipid Interconversion and Transport Are Altered in Glaucoma

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Decreased phosphatidylserine (PS) and increased phosphatidylethanolamine (PE) occur in both trabecular meshwork (TM) cells and aqueous humor due to aberrant phosphatidylserine decarboxylase (PSD) over‐expression, and variation in levels of individual PS or PE species differing by only a few acyl chains occurs due to impaired lipid transport due to ...
Genea Edwards, Ruminder Kaur, Anna Mueller, Noël Ziebarth, Richard K. Lee, Sanjoy K. Bhattacharya   +5 more
wiley   +1 more source

Corneal Densitometry Changes after Epithelium-Off Corneal Collagen Crosslinking

QJM: An International Journal of Medicine, 2021
Abstract Background Keratoconus is a progressive non-inflammatory, degenerative disease that affects the integrity of the collagen matrix within the corneal stroma. Corneal cross-linking (CXL) has been described as the only modality in halting the disease progression over the past decade.
Karim N Abbas, Raafat A. El Sayed, Mouamen M Mostafa   +2 more
openaire   +1 more source

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

Advanced Science, Volume 13, Issue 3, 14 January 2026.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu, Bixiao Liu, Yu Yang, Tao Meng, Yuanyuan Chang, Yao Peng, Jia Guo, Zhuqing Wang, Hongqian Guo, Liuhua Zhou, Xiaozhi Zhao   +10 more
wiley   +1 more source

Corneal densitometry analysis in patients diagnosed with keratoconus

Acta Ophthalmologica, 2022
AbstractPurposeThe purpose of this study is to carry out a comparative study of corneal densitometry (COD) using Pentacam HR in two groups of patients. A control group of normal eyes where corneal pathology has been ruled out and another group of patients diagnosed with keratoconus (KC) who have not received corneal Cross‐Linking as treatment ...
Marta Orejudo Derivas, Ana Boned‐Murillo, Mª Dolores Díaz‐Barreda, Ismael Bakkali El Bakkali, Guillermo Pérez Rivasés, Eva Josefina Núñez Moscarda, Pablo Cisneros, María Ángeles Del Buey Sayas   +7 more
openaire   +1 more source

Selective knockout of murine glutamic acid‐rich protein 2 significantly alters dark continuous noise in rod photoreceptors

The Journal of Physiology, Volume 604, Issue 1, Page 460-478, 1 January 2026.
Abstract figure legend GARP2 has a minor role in maintaining the structural integrity of the rod outer segments as a function of age, but an important role in regulating rod photoreceptor continuous noise, likely through stabilization of PDE6 basal activity.
Delores A. Stacks, Ulisse Bocchero, Marci L. DeRamus, Mai N. Nguyen, Jeffrey Messinger, Timothy W. Kraft, Steven J. Pittler, Johan Pahlberg   +7 more
wiley   +1 more source

Preferential Myosin Heavy Chain Isoform B Expression May Contribute to the Faster Velocity of Contraction in Veins versus Arteries [PDF]

, 2007
Smooth muscle myosin heavy chains occur in 2 isoforms, SMA (slow) and SMB (fast). We hypothesized that the SMB isoform is predominant in the faster-contracting rat vena cava compared to thoracic aorta.
Eddinger, Thomas, Fink, Gregory D, Kayal, Anas, Rondelli, Catherine M, Rovner, Arthur S, Szasz, Irina T, Thakali, Keshari, Watson, Ralph E, Watts, Stephanie W   +8 more
core   +1 more source

Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy. [PDF]

, 2019
Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules.
Andersen, Julie, Butler, Victoria J, Chamoli, Manish, Jung, Manfred, Kao, Aimee W, Ng, Che-Ping, Simon, Roman P, Tezil, Tugsan, Verdin, Eric   +8 more
core   +1 more source

Buyang Huanwu Decoction Alleviates Chronic Intermittent Hypoxia–Induced Myocardial Inflammation and Fibrosis via the NF‐κB/LOX Signaling Pathway

Human Mutation, Volume 2026, Issue 1, 2026.
Objective To investigate the protective effects of Buyang Huanwu decoction (BYHW) on myocardial injury induced by chronic intermittent hypoxia (CIH) in rats and to analyze its potential regulatory mechanism through the NF‐κB/LOX signaling pathway. Methods Then, 36 adult male Sprague–Dawley (SD) rats (weighing 200–250 g) were randomly divided into six ...
Lijun Ou, Chenyi Liu, Weicheng Zhao, Cairu Liu, Ye Ning, Minghua Ren   +5 more
wiley   +1 more source

Anterior Chamber Characteristics, Endothelial Parameters, and Corneal Densitometry After Descemet Stripping Automated Endothelial Keratoplasty in Patients With Fuchs Dystrophy

Journal of Ophthalmic & Vision Research, 2021
Purpose: To compare anterior segment parameters in patients with Fuchs endothelial dystrophy (FED) who underwent Descemet stripping automated endothelial keratoplasty (DSAEK) in one eye and no corneal surgery in the fellow eye.
Remzi Karadag, Kristin M. Hammersmith, Parveen K. Nagra, Christopher J. Rapuano   +3 more
doaj   +1 more source

Differential Quantitative Proteomics of Human Microvascular Endothelial Cells 1 by iTRAQ Reveals Palladin to be a New Biomarker During TGF-β1 Induced Endothelial Mesenchymal Transition [PDF]

, 2017
The study uses global quantitative proteomics to investigate the molecular mechanisms behind the induction of endothelial-mesenchymal transition (EndMT) by transforming growth factor–β (TGF-β).
Bednarek, Radosław, Gawryś, Katarzyna, Popielarsk, Marcin, Sitkiewicz, Ewa, Stasiak, Marta, Studzian, Maciej, Swiatkowska, Maria, Szemraj, Janusz   +7 more
core   +1 more source