Results 61 to 70 of about 96,845 (174)

Spatial multi‐omics unveils sphingolipid metabolic reprogramming within the retinal pathological niche

iMeta, Volume 5, Issue 4, August 2026.
Spatial multi‐omics of the mouse ocular globe after retinal ischemia‐reperfusion (RIR) injury identifies the ganglion cell layer (GCL) as an immunometabolic niche where Trem2+ microglia closely associate with stressed retinal ganglion cells (RGCs) through Trem2‐Apoe signaling.
Yunhong Shi, Jinpei Lin, Yi Wu, Shengsong Xu, Naiyuan Zhang, Yiji Pan, Anli Ren, Ying Fang, Yu Huang, Xiayin Zhang, Zhuoting Zhu, Yehong Zhuo, Honghua Yu   +12 more
wiley   +1 more source

Protein kinase Cδ and pharmacomechanical coupling: Re‐envisioning cerebral vascular control

The Journal of Physiology, Volume 604, Issue 15, Page 6324-6347, 1 August 2026.
Abstract figure legend Top, G‐protein coupled receptors trigger electromechanical and pharmacomechanical coupling, the latter via signal transduction pathways that inhibit myosin light chain phosphatase. Middle, the relative contribution of electromechanical and pharmacomechanical coupling varies with the concentration and the vessel area to which ...
Nadia Haghbin, Michelle S. M. Kim, Mohammed El‐lakany, David M. Richter, Dabasish Kumar Saha, Galina Yu. Mironova, David A. Steven, Jonathan C. Lau, Mel Boulton, Nikolaos M. Tsoukias, Donald G. Welsh   +10 more
wiley   +1 more source

Changes in the corneal densitometry values at different time points with various corneal diameters.

, 2022
Changes in the corneal densitometry values at different time points with various corneal diameters.
Lili Jing (254220), Lianghui Zhao (11539166), Jie Li (15030), Xianli Du (6280370)   +3 more
core   +1 more source

Loss of Corneal Nerves and Corneal Haze in Patients with Fuchs’ Endothelial Corneal Dystrophy with the Transcription Factor 4 Gene Trinucleotide Repeat Expansion

Ophthalmology Science, 2023
Objective: Seventy percent of Fuchs’ endothelial corneal dystrophy (FECD) cases are caused by an intronic trinucleotide repeat expansion in the transcription factor 4 gene (TCF4). The objective of this study was to characterize the corneal subbasal nerve
Matthew Gillings, MD, Andrew Mastro, MD, Xunzhi Zhang, Kelly Kiser, MD, Jane Gu, Chao Xing, PhD, Danielle M. Robertson, OD, PhD, W. Matthew Petroll, PhD, V. Vinod Mootha, MD   +8 more
doaj   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

Assessment of Early Fuchs Endothelial Corneal Dystrophy and CTG Trinucleotide Expansion Positivity Using Scheimpflug Imaging

Ophthalmology Science
Purpose: To evaluate changes in corneal densitometry and optical aberrations using Scheimpflug imaging in early Fuchs endothelial corneal dystrophy (FECD) and to assess their association with CTG trinucleotide repeat expansion.
Stanley S.J. Poh, MBBS, Kai Yuan Tey, MBBS, Gary S.L. Peh, PhD, Dawn J.H. Neo, MSc, Hla Myint Htoon, PhD, Evan K.L. Lee, Yu Qiang Soh, MBBS, V Vinod Mootha, MD, Jodhbir S. Mehta, PhD   +8 more
doaj   +1 more source

Corneal Densitometry Changes after Epithelium-Off Corneal Collagen Crosslinking

QJM: An International Journal of Medicine, 2021
Abstract Background Keratoconus is a progressive non-inflammatory, degenerative disease that affects the integrity of the collagen matrix within the corneal stroma. Corneal cross-linking (CXL) has been described as the only modality in halting the disease progression over the past decade.
Karim N Abbas, Raafat A. El Sayed, Mouamen M Mostafa   +2 more
openaire   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, Volume 59, Issue 7, July 2026.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

Evaluation of corneal transplantation [PDF]

, 1997
Editorial / comment on corneal ...
Coster, Douglas John
core  

Small Incision Lenticule Extraction for Correction of Myopia and Myopic Astigmatism: First 24-Hour Outcomes

Journal of Ophthalmology, 2017
Purpose. To observe the first 24-hour (h) outcomes of the small incision lenticule extraction procedure (SMILE) for myopia and myopic astigmatism. Methods.
Taixiang Liu, Tingting Dan, Yan Luo
doaj   +1 more source