Results 121 to 130 of about 186,523 (222)
Advanced Science, Volume 12, Issue 16, April 24, 2025.A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu +10 more
wiley +1 more source
Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring [PDF]
, 2016 Mucous membrane pemphigoid (MMP) is a systemic mucosal scarring disease, commonly causing blindness, for which there is no antifibrotic therapy. Aldehyde dehydrogenase (ALDH) family 1 is upregulated in both ocular MMP (OMMP) conjunctiva and cultured ...
Abraham, DJ +9 more
core +1 more source
The FASEB Journal, Volume 39, Issue 5, 15 March 2025.Schematic representation outlining the proposed role of the vitamin A receptor RBPR2 in maintaining whole‐body retinoid homeostasis. Abstract The distribution of stored dietary vitamin A/all‐trans‐retinol (ROL) from the liver throughout the body is critical for maintaining retinoid function in peripheral tissues and for generating visual pigments for ...
Rakesh Radhakrishnan +4 more
wiley +1 more source
Corneal light scattering and anterior segment findings in rheumatoid arthritis patients: a prospective study on disease monitoring [PDF]
International Journal of OphthalmologyAIM: To evaluate changes in corneal light scattering and anterior segment parameters in newly diagnosed rheumatoid arthritis (RA) patients who achieved remission with systemic treatment, compared to healthy controls.
Serife Ciloglu Hayat +3 more
doaj +1 more source
The FASEB Journal, Volume 39, Issue 3, 15 February 2025.Activation of transcription factors such as HIF‐1α underlie retinal neovascularization, a hallmark of proliferative diabetic retinopathy (PDR). Ref‐1 regulates HIF‐1α by reducing cysteine residues on HIF‐1α, allowing it to bind to hypoxia‐response elements (HRE) and promote the transcription of pro‐angiogenic target genes.
Gabriella D. Hartman +12 more
wiley +1 more source
Short-term effects of microstructured surfaces: role in cell differentiation toward a contractile phenotype [PDF]
, 2015 Cell adhesion plays a key role in cell behavior, in terms of migration, proliferation, differentiation and apoptosis. All of these events concur with tissue regeneration and remodeling mechanisms, integrating a complex network of intracellular signaling ...
Ana Marina Ferreira +5 more
core +1 more source
Analysis of the correlation between biomechanical properties and corneal densitometry in myopic eyes [PDF]
, 2022 Yuwei Zheng +5 more
openalex +1 more source
British Journal of Pharmacology, Volume 182, Issue 4, Page 951-968, February 2025.Background and Purpose Angiogenesis is a pathological component of neovascular age‐related macular degeneration. Current therapies, although successful, are prone to high levels of patient non‐response and a loss of efficacy over time, indicating the need to explore other therapeutic avenues. We have shown that an interaction between syndecan‐2 and the
Samantha Arokiasamy +11 more
wiley +1 more source
Corneal densitometry and biomechanical properties in patients with primary congenital glaucoma [PDF]
, 2021 Laura Morales‐Fernández +9 more
openalex +1 more source
Journal of Ophthalmology, Volume 2025, Issue 1, 2025.Background To evaluate visual acuity outcome after excimer laser phototherapeutic keratectomy (PTK) for epithelial basement membrane dystrophy (EBMD) and to provide new insights into higher‐order aberrations (HOAs) and corneal density changes. Methods In this single‐center cohort, 92 eyes from 80 individuals underwent PTK for EBMD, with follow‐up ...
Simon Helm +6 more
wiley +1 more source