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Neurotrophic factors and corneal nerve regeneration [PDF]
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Lambiase, Alessandro, Sacchetti, Marta
core +2 more sources
Nanomedicine Approaches for Corneal Diseases [PDF]
Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions. However, barrier properties of the ocular surface necessitate high concentration of the drugs applied in the eye ...
Shyam Chaurasia+3 more
openaire +3 more sources
HEREDITARY HEMORRHAGIC TELANGIECTASIA
We describe a patient with clinical history of intermittent haemolacria associated to hereditary hemorrhagic telangiectasia, first seen and diagnosed by the ophthalmologist.
Messody Zagury+5 more
doaj +1 more source
Corneal stromal demarcation line after collagen cross-linking in corneal ectatic diseases: a review of the literature [PDF]
Collagen cross-linking (CXL) is a relatively new conservative approach for progressive corneal ectasia, which is able to strengthen corneal tissue reforming new covalent bonds.
SPADEA, LEOPOLDO+2 more
core +1 more source
Surfactant protein D contributes to ocular defense against Pseudomonas aeruginosa in a murine model of dry eye disease. [PDF]
Dry eye disease can cause ocular surface inflammation that disrupts the corneal epithelial barrier. While dry eye patients are known to have an increased risk of corneal infection, it is not known whether there is a direct causal relationship between ...
Evans, David+4 more
core +6 more sources
AIM: To investigate the effects of bovine pituitary extract on the proliferation of keratocytes and maintaining the keratocyte phenotype in vitro.METHODS: Single keratocytes were isolated by enzyme digestion for in vitro culture.
Zhong-Zhong Xu +4 more
doaj +1 more source
Neurotrophic keratitis in a patient with disseminated lymphangiomatosis. [PDF]
INTRODUCTION: Neurotrophic keratitis, a degenerative corneal disease caused by trigeminal nerve impairment, has many etiologies and remains very difficult to treat.
Charukamnoetkanok, Puwat+2 more
core +2 more sources
Corneal diseases are common in domestic rabbits. It is important to carefully evaluate the cornea and the entire eye when rabbit present with clinical signs such as squinting, tearing, or conjunctival hyperemia. Complete ophthalmic examination and general physical examination should be performed on all rabbits with corneal disease. Important diagnostic
Department of Comparative Ophthalmology, Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100126, Gainesville, FL 32610-0126, USA ( host institution )+1 more
openaire +4 more sources
Corneal nerves in health and disease [PDF]
The cornea is the most sensitive structure in the human body. Corneal nerves adapt to maintain transparency and contribute to corneal health by mediating tear secretion and protective reflexes and provide trophic support to epithelial and stromal cells.
Mouhamed Al-Aqaba+5 more
openaire +3 more sources