Results 11 to 20 of about 9,089,625 (306)
Determining Progression in Ectatic Corneal Disease
Asia - Pacific Journal of Ophthalmology, 2020 Before the advent of modern tomographic imaging and corneal cross-linking (CXL), diagnosis and treatment of ectatic disease were limited to disease severity where changes on the anterior corneal surface lead to visual complaints. Rigid contact lenses and/
M. Belin +5 more
semanticscholar +1 more source
The IGF/Insulin-IGFBP Axis in Corneal Development, Wound Healing, and Disease
Frontiers in Endocrinology, 2020 The insulin-like growth factor (IGF) family plays key roles in growth and development. In the cornea, IGF family members have been implicated in proliferation, differentiation, and migration, critical events that maintain a smooth refracting surface that
Whitney L. Stuard +2 more
semanticscholar +1 more source
Surfactant protein D contributes to ocular defense against Pseudomonas aeruginosa in a murine model of dry eye disease. [PDF]
, 2013 Dry eye disease can cause ocular surface inflammation that disrupts the corneal epithelial barrier. While dry eye patients are known to have an increased risk of corneal infection, it is not known whether there is a direct causal relationship between ...
Evans, David +4 more
core +6 more sources
Nanomedicine Approaches for Corneal Diseases [PDF]
Journal of Functional Biomaterials, 2015 Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions. However, barrier properties of the ocular surface necessitate high concentration of the drugs applied in the eye ...
Shyam Chaurasia +3 more
openaire +3 more sources
Neurotrophic factors and corneal nerve regeneration [PDF]
, 2017 The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Lambiase, Alessandro, Sacchetti, Marta
core +2 more sources
Corneal stromal demarcation line after collagen cross-linking in corneal ectatic diseases: a review of the literature [PDF]
, 2016 Collagen cross-linking (CXL) is a relatively new conservative approach for progressive corneal ectasia, which is able to strengthen corneal tissue reforming new covalent bonds.
SPADEA, LEOPOLDO +2 more
core +1 more source
Veterinary Clinics of North America: Exotic Animal Practice, 2002 Corneal diseases are common in domestic rabbits. It is important to carefully evaluate the cornea and the entire eye when rabbit present with clinical signs such as squinting, tearing, or conjunctival hyperemia. Complete ophthalmic examination and general physical examination should be performed on all rabbits with corneal disease. Important diagnostic
Department of Comparative Ophthalmology, Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100126, Gainesville, FL 32610-0126, USA ( host institution ) +1 more
openaire +4 more sources
Neurotrophic keratitis in a patient with disseminated lymphangiomatosis. [PDF]
, 2009 INTRODUCTION: Neurotrophic keratitis, a degenerative corneal disease caused by trigeminal nerve impairment, has many etiologies and remains very difficult to treat.
Charukamnoetkanok, Puwat +2 more
core +2 more sources
A Review of the Cytokine IL-17 in Ocular Surface and Corneal Disease
Current Eye Research, 2018 Aim: To investigate the role of interleukin-17 in ocular surface and corneal disease. Ocular surface and corneal disease is a leading cause of blindness and is an ongoing challenge for the public health sector to implement effective therapies.
K. B. Garbutcheon-Singh +8 more
semanticscholar +1 more source
Phase I trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]
, 2018 Neurotrophic keratitis/keratopathy (NK), a rare degenerative corneal disease, lacks effective pharmacologic therapies.1 Because NK pathology involves trigeminal nerve damage and loss of corneal innervation, nerve growth factor (NGF) is surmised to ...
Alio, Jorge +45 more
core +1 more source