Results 71 to 80 of about 9,089,625 (306)

Retinal regions shape human and murine Müller cell proteome profile and functionality

Glia, Volume 71, Issue 2, Page 391-414, February 2023., 2023
Main Points We defined Müller cells heterogeneity in the macular and peripheral human retina. Signaling pathways shaping this glial heterogeneity include proteins important for interaction with vesicular secretion, extracellular matrix and cell adhesion.
Lew Kaplan, Corinne Drexler, Anna M. Pfaller, Santra Brenna, Kirsten A. Wunderlich, Andrea Dimitracopoulos, Juliane Merl‐Pham, Maria‐Theresa Perez, Ursula Schlötzer‐Schrehardt, Volker Enzmann, Marijana Samardzija, Berta Puig, Peter Fuchs, Kristian Franze, Stefanie M. Hauck, Antje Grosche   +15 more
wiley   +1 more source

Corneal Pachymetry by AS-OCT after Descemet's Membrane Endothelial Keratoplasty [PDF]

arXiv, 2021
Corneal thickness (pachymetry) maps can be used to monitor restoration of corneal endothelial function, for example after Descemet's membrane endothelial keratoplasty (DMEK). Automated delineation of the corneal interfaces in anterior segment optical coherence tomography (AS-OCT) can be challenging for corneas that are irregularly shaped due to ...
arxiv  

Limbal stem cell transplantation: clinical results, limits, and perspectives [PDF]

, 2018
Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and in an invasion of the cornea by the conjunctival epithelium.
Bruscolini, Alice, Lambiase, Alessandro, Rama, Paolo, Sacchetti, Marta   +3 more
core   +1 more source

Abnormal activity of corneal cold thermoreceptors underlies the unpleasant sensations in dry eye disease

Pain, 2015
Dry eye disease (DED) affects >10% of the population worldwide, and it provokes an unpleasant sensation of ocular dryness, whose underlying neural mechanisms remain unknown. Removal of the main lachrymal gland in guinea pigs caused long-term reduction of
Illés Kovács, C. Luna, S. Quirce, K. Mizerska, Gerard Callejo, A. Riestra, L. Fernández-Sánchez, V. Meseguer, N. Cuenca, J. Merayo-Lloves, M. Acosta, X. Gasull, C. Belmonte, J. Gallar   +13 more
semanticscholar   +1 more source

Enhancing Form Stability: Shrink‐Resistant Hydrogels Made of Interpenetrating Networks of Recombinant Spider Silk and Collagen‐I

Advanced Healthcare Materials, EarlyView.
A shrinkage‐resistant hydrogel is developed to confer post‐fabrication shape fidelity. The hydrogel, based on recombinant spider silk protein eADF4(C16)‐RGD and collagen‐I, exhibits tunable mechanical properties and shrink‐resistance in the presence of fibroblasts as well as muscle cells.
Xuen J. Ng, Tilman U. Esser, Vanessa T. Trossmann, Christoph Rudisch, Maren Fiedler, Kaveh Roshanbinfar, Zan Lamberger, Philipp Stahlhut, Gregor Lang, Thomas Scheibel, Felix B. Engel   +10 more
wiley   +1 more source

Assessment of Biomechanical Properties for Corneal Post Refractive Surgery [PDF]

arXiv, 2022
A stable shape for corneas experiencing refractive surgery has to be sustained so as to elude post-refractive surgery de-compensation. This de-compensation leads to visual complications and unsatisfactory procedure recovery. Variation in corneal lamellae and collagen fibres is induced by recent LASER refractive surgical procedures utilizing LASER ...
arxiv  

Overexpression of MMPs in Corneas Requiring Penetrating and Deep Anterior Lamellar Keratoplasty. [PDF]

, 2019
PurposeMatrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases involved in wound healing processes, including neovascularization and fibrosis. We assessed MMP protein expression levels in diseased corneas of patients requiring
Chan, Matilda F, Clay, Selene M, Hwang, David G, Oldenburg, Catherine E, Rose-Nussbaumer, Jennifer, Wolf, Marie   +5 more
core  

Minocycline is cytoprotective in human corneal endothelial cells and induces anti-apoptotic B-cell CLL/lymphoma 2 (Bcl-2) and X-linked inhibitor of apoptosis (XIAP) [PDF]

, 2010
Introduction Loss of corneal endothelial cells (CECs) is one major factor limiting transplant clarity and survival after keratoplasty. Amongst other factors, apoptosis due to cellular stress is responsible for these problems.
Hirneiß, Christoph, Kampik, Anselm, Kernt, Marcus, Neubauer, Aljoscha Steffen   +3 more
core   +3 more sources

Global Survey of Corneal Transplantation and Eye Banking.

JAMA ophthalmology, 2016
IMPORTANCE Corneal transplantation restores visual function when visual impairment caused by a corneal disease becomes too severe. It is considered the world's most frequent type of transplantation, but, to our knowledge, there are no exhaustive data ...
P. Gain, R. Jullienne, Zhiguo He, M. Aldossary, S. Acquart, F. Cognasse, G. Thuret   +6 more
semanticscholar   +1 more source

Photonic Nanomaterials for Wearable Health Solutions

Advanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park, Jung Woo Leem, Young L. Kim, Chi Hwan Lee   +3 more
wiley   +1 more source