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Corneal Dystrophies [PDF]

open access: yesNature Reviews Disease Primers, 2020
Corneal dystrophies are broadly defined as inherited disorders that affect any layer of the cornea and are usually progressive, bilateral conditions that do not have systemic effects.
Jodhbir S Mehta   +2 more
exaly   +8 more sources
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Corneal dystrophies

Journal Français d'Ophtalmologie, 2017
Degenerative or hereditary corneal diseases are sometimes difficult to discriminate. Corneal dystrophies affect approximately 0.09 % of the population. They are identified by the IC3D classification based on their phenotype, genotype and evidence gathered for their diagnosis.
Møller, Hans Ulrik, Lee, Barry
openaire   +5 more sources

Fuchs’ Corneal Dystrophy [PDF]

open access: yesExpert Review of Ophthalmology, 2010
Fuchs' corneal dystrophy (FCD) is a progressive, hereditary disease of the cornea first described a century ago by the Austrian ophthalmologist Ernst Fuchs. Patients often present in the fifth to sixth decade of life with blurry morning vision that increases in duration as the disease progresses.
Allen O Eghrari, John D Gottsch
exaly   +3 more sources

Biochemical Mechanisms of Aggregation in TGFBI-Linked Corneal Dystrophies [PDF]

open access: yesProgress in Retinal and Eye Research, 2020
Transforming growth factor-β-induced protein (TGFBIp), an extracellular matrix protein, is the second most abundant protein in the corneal stroma. In this review, we summarize the current knowledge concerning the expression, molecular structure, binding ...
Lawrence Dedionisio   +2 more
exaly   +2 more sources

Fuchs Corneal Dystrophy

Progress in Molecular Biology and Translational Science, 2015
Fuchs corneal dystrophy (FCD) is a hereditary, progressive disease of the posterior cornea which results in excrescences of Descemet membrane, endothelial cell loss, corneal edema, and, in late stages, bullous keratopathy. Structural changes are noted principally in Descemet membrane and the endothelium, with thickening of Descemet membrane, loss of ...
S Amer Riazuddin   +2 more
exaly   +3 more sources

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