Results 51 to 60 of about 494 (157)

The Effect of Upper Eyelid Blepharoplasty on Corneal Tomography and Epithelial Profile

Clinical Ophthalmology, 2023
Pedro Carreira, Tomás Loureiro, Ana Rita Carreira, Filipe Gouveia-Moraes, Ana Cardoso, Audrey Sampaio, Paul Campos, Sandra Rodrigues-Barros, Ines Machado, Nuno Campos Centro de Responsabilidade Integrada de Oftalmologia, Hospital Garcia de Orta, Almada ...
Carreira P, Loureiro T, Carreira AR, Gouveia-Moraes F, Cardoso A, Sampaio A, Campos P, Rodrigues-Barros S, Machado I, Campos N   +9 more
doaj  

Corneal biomechanical changes in allergic conjunctivitis

Eye and Vision, 2021
Background To explore corneal biomechanical changes, identify related factors and determine early indicators of keratoconus (KC) development risk in allergic conjunctivitis (AC) patients.
Qian Wang, Yuqing Deng, Saiqun Li, Xinyue Du, Xuan Zhao, Tingting Zhang, Jin Yuan   +6 more
doaj   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

Comparison of the repeatability and reproducibility of corneal thickness mapping using optical coherence tomography according to tear film break-up time

BMC Ophthalmology
Background To compare the repeatability and reproducibility of corneal and corneal epithelial thickness mapping using anterior segment optical coherence tomography (AS-OCT) according to tear film break-up time (TBUT).
Kan Lin, Zhiqiang Xu, Hui Wang, Yuzhou Wang, Linzhi Wei, Hongqing Ma, Jian Zhao, Fan Lu, Liang Hu   +8 more
doaj   +1 more source

Corneal Epithelial Remodeling after LASIK Measured by Fourier-Domain Optical Coherence Tomography

Journal of Ophthalmology, 2015
Purpose. To quantify corneal epithelial thickness changes after myopic LASIK by OCT. Methods. Epithelial thickness before and after myopic LASIK were measured by a Fourier-domain OCT system.
Maolong Tang, Yan Li, David Huang
doaj   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Age-Related Changes in Corneal Epithelial Thickness Measured with an Ultrasound Pachymeter

Clinical Interventions in Aging, 2022
There is increasing research on the aging process of the cornea and its effect on the corneal parameters measured objectively. Nevertheless, the association of corneal epithelial thickness (CET) with age has yet to be fully illustrated.We aimed to measure CET in healthy subjects to determine its age-related variation by using an ultrasound device.A ...
Ahmet Colakoglu, Cemile Banu Cosar
openaire   +3 more sources

Construction of a full-thickness human corneal substitute from anterior acellular porcine corneal matrix and human corneal cells [PDF]

International Journal of Ophthalmology, 2019
AIM: To construct functional human full-thickness corneal replacements. METHODS: Acellular porcine corneal matrix (APCM) was developed from porcine cornea by decellulariztion.
Kai Zhang, Xiao-Xiao Ren, Ping Li, Kun-Peng Pang, Hong Wang   +4 more
doaj   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source