Results 31 to 40 of about 444,196 (307)

Elucidating the mechanism of corneal epithelial cell repair: unraveling the impact of growth factors

Frontiers in Medicine
The repair mechanism for corneal epithelial cell injuries encompasses migration, proliferation, and differentiation of corneal epithelial cells, and extracellular matrix remodeling of the stromal structural integrity.
Jinjin Gong, Jinjin Gong, Gang Ding, Zhongkai Hao, Zhongkai Hao, Yuchun Li, Aijun Deng, Chenming Zhang, Chenming Zhang   +8 more
doaj   +1 more source

Stem Cell Spheres for Corneal Regeneration

, 2021
Corneal cells isolated from the peripheral cornea and limbus can be cultured in vitro under sphere-forming conditions which enrich for stem and progenitor cells. These stem cell-enriched spheres represent a mixed population of cells comprising epithelial,
Li, Ye, Ismail, Salim, Huang, Stephanie U-Shane, McGhee, Jennifer J, Yoon, Jinny Jung, Sherwin, Trevor, Wadhwa, Himanshu, Mathan, Jeremy John   +7 more
core   +1 more source

PAX6/CXCL14 regulatory axis promotes the repair of corneal injury by enhancing corneal epithelial cell proliferation

Journal of Translational Medicine
Background Corneal injuries, often leading to severe vision loss or blindness, have traditionally been treated with the belief that limbal stem cells (LSCs) are essential for repair and homeostasis, while central corneal epithelial cells (CCECs) were ...
Ruijue Ma, Yingxi Li, Xiaoli Dong, Yiming Zhang, Xiaosu Chen, Yue Zhang, Haohan Zou, Yan Wang   +7 more
doaj   +1 more source

Evaluation of corneal transplantation [PDF]

, 1997
Editorial / comment on corneal ...
Coster, Douglas John
core  

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

Advanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han, Shuvra Mondal, Sungkeun Han, Chan‐Hwi Eom, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +5 more
wiley   +1 more source

Nanoparticle-mediated inhibition of Yes-associated protein prevents corneal scarring after traumatic injury

Materials Today Bio
Corneal scars develop during the regenerative process following traumatic injuries. Verteporfin (VP), a Yes-associated protein (YAP) inhibitor, has shown promise as an antifibrotic agent, but its application to the ocular surface is limited by ...
Nae-Won Kang, Kyeongwoo Jang, Hyeonji Kim, Li Jiang, Youngyoon Amy Seo, Euisun Song, Julian Garcia-Sanchez, Danting Lin, Fang Chen, Uiyoung Han, Wendy W. Liu, David Myung   +11 more
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Arginine depletion as a mechanism for the immune privilege of corneal allografts. [PDF]

, 2011
The cornea is an immune privileged tissue. Since arginase has been found to modulate T-cell function by depleting arginine, we investigated the expression of arginase in the cornea and its possible role in immune privilege using a murine transplant model.
Larkin, Daniel FP, George, Andrew J.T., Fu, Hongmei, Coe, D, Hongmei Fu, Chai, J-G, Zaher, S, David Coe, George, Andrew JT, Fu, H, Khan, A, Larkin, Daniel F.P., Jian-Guo Chai, Ingrid Müller, Kropf, P, Müller, Ingrid, Kropf, Pascale, Larkin, DFP, George, AJT, Adnan Khan, Khan, Adnan, Zaher, Sarah, Daniel F. P. Larkin, Mueller, I, Pascale Kropf, Coe, David, Sarah Zaher, Andrew J. T. George, Chai, Jian-Guo   +28 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Reverse engineering as a teaching tool: the corneal topographer [PDF]

, 2012
Reverse engineering is the process of discovering the technological principles of a device, object or system through analysis of its structure, function, and operation.
Mas, David, Illueca Contri, Carlos, Pérez Rodríguez, Jorge, Espinosa, Julián, Hernández, Consuelo, Roig Hernández, Ana Belén, Vázquez Ferri, Carmen   +6 more
core   +2 more sources