Results 1 to 10 of about 16,319 (140)

Corneal melting following intrastromal injection of bevacizumab for corneal neovascularization [PDF]

Oman Journal of Ophthalmology
The aim is to report corneal melting following intrastromal injection of antivascular endothelial growth factor (anti-VEGF), bevacizumab, for pre-existing corneal neovascularization.
Muna Salim Al-Ruhaili, Haitham Hilal Al-Mahrouqi   +1 more
doaj   +2 more sources

Novel artemisinin derivative P31 inhibits VEGF-induced corneal neovascularization through AKT and ERK1/2 pathways [PDF]

Heliyon
Corneal neovascularization (CoNV)is a major cause of blindness in many ocular diseases. Substantial evidence indicates that vascular endothelial growth factor (VEGF) plays an important role in the pathogenesis of corneal neovascularization.
Wen Ding, Yingxue Su, Jianshan Mo, Danyuan Sun, Chen Cao, Xiaolei Zhang, Yandong Wang   +6 more
doaj   +2 more sources

Shark Cartilage-Derived Anti-Angiogenic Peptide Inhibits Corneal Neovascularization [PDF]

Bioengineering
Corneal neovascularization is a significant cause of vision loss, often resulting in corneal clouding and chronic inflammation. Shark cartilage is widely recognized as a significant natural source of anti-angiogenic compounds.
Yunxian Li, Aoke Chen, An Hong, Sheng Xiong, Xiaojia Chen, Qiuling Xie   +5 more
doaj   +2 more sources

Aganirsen as a Therapeutic Alternative for Modulating Corneal Neovascularization: A Real-World Case Series Study [PDF]

Clinical Ophthalmology
Salvador García-Delpech,1 Sara Fathi Nieto,2 Ana Hervás Ontiveros,2,3 Patricia Udaondo,1,2 Damian Garcia-Teillard1,4 1Aiken Ophthalmological Clinic and Aiken Foundation, Valencia, Spain; 2Department of Ophthalmology, Hospital Universitario Y Politécnico ...
García-Delpech S, Fathi Nieto S, Hervás Ontiveros A, Udaondo P, Garcia-Teillard D   +4 more
doaj   +2 more sources

Challenge of Corneal Ulcer Healing: A Novel Conceptual Framework, the “Triad” of Corneal Ulcer Healing/Corneal Neovascularization/Intraocular Pressure, and Avascular Tendon Healing, for Evaluation of Corneal Ulcer Therapy, Therapy of Neovascularization, Glaucoma Therapy, and Pentadecapeptide BPC 157 Efficacy [PDF]

Pharmaceuticals
To better address the challenge of corneal ulcer healing, with already available standard agents, and those recently introduced, such as stable gastric pentadecapeptide BPC 157, we introduced a novel conceptual framework—the “triad” of corneal ulcer ...
Sanja Masnec, Antonio Kokot, Tamara Kralj, Mirna Zlatar, Kristina Loncaric, Marko Sablic, Miro Kalauz, Iva Beslic, Katarina Oroz, Bozana Mrvelj, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Borna Staresinic, Goran Slivsek, Alenka Boban Blagaic, Sven Seiwerth, Anita Skrtic, Predrag Sikiric   +18 more
doaj   +2 more sources

Genome Editing VEGFA Prevents Corneal Neovascularization In Vivo [PDF]

Advanced Science
Corneal neovascularization (CNV) is a common clinical finding seen in a range of eye diseases. Current therapeutic approaches to treat corneal angiogenesis, in which vascular endothelial growth factor (VEGF) A plays a central role, can cause a variety of
Zhenhai Zeng, Siheng Li, Xiuhong Ye, Yiran Wang, Qinmei Wang, Zhongxing Chen, Ziqian Wang, Jun Zhang, Qing Wang, Lu Chen, Shuangzhe Zhang, Zhilin Zou, Meimin Lin, Xinyi Chen, Guoli Zhao, Colm McAlinden, Hetian Lei, Xingtao Zhou, Jinhai Huang   +18 more
doaj   +2 more sources

Studying the effect of intrastromal anti-vascular endothelial growth factor injections on corneal neovascularization using optical coherence tomography angiography

Journal of the Egyptian Ophthalmological Society, 2023
Purpose To evaluate the effect of intrastromal injection of anti-vascular endothelial growth factor (Anti-VEGF) on corneal neovascularization using spectral domain Optical coherence tomography angiography imaging (OCTA).
Hussein Mohamed Sherif Ahmed Ayoub, Amr Saleh Mousa, Momen Mahmoud Hamdi, Rasha Mohamed Mousa, Mo′mena Ahmad A Awad-Allah   +4 more
doaj   +1 more source

AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model

Cell Communication and Signaling, 2022
Background Apoptosis signal-regulating kinase 1-interacting protein 1 (AIP1) participates in inflammatory neovascularization induction. NADPH oxidase 4 (NOX4) produces reactive oxygen species (ROS), leading to an imbalance in nucleotide-binding ...
Qingyu Li, Xia Hua, Liangpin Li, Xueyan Zhou, Ye Tian, Yang Deng, Min Zhang, Xiaoyong Yuan, Wei Chi   +8 more
doaj   +1 more source

Topically administered bevacizumab had longer standing anti-angiogenic effect than subconjunctivally injected bevacizumab in rat corneal neovacularization [PDF]

International Journal of Ophthalmology, 2013
AIM: To compare the effect of topically administered and subconjunctivally injected bevacizumab on experimental corneal neovascularization in rats for two weeks after treatment.METHODS: Twenty-eight Sprague-Dawley rats were divided into four groups of 7 ...
Jae Yong Kim, Dong Yoon Kim, Eun-Soon Kim, Myoung Joon Kim, Hungwon Tchah   +4 more
doaj   +1 more source

Regression of corneal opacity and neovascularization in Stevens-Johnson syndrome and Toxic Epidermal Necrolysis with the use of prosthetic replacement of the ocular surface ecosystem (PROSE) treatment

American Journal of Ophthalmology Case Reports, 2022
Purpose: To report two cases demonstrating the regression of corneal neovascularization and clearing of corneal opacification in patients with Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) undergoing prosthetic replacement of the ...
Jennifer Liao, OD, Bita Asghari, OD, Karen G. Carrasquillo, OD, PhD   +2 more
doaj   +1 more source