Results 1 to 10 of about 15,651 (160)

Therapeutic approaches for corneal neovascularization [PDF]

Eye and Vision, 2017
Angiogenesis refers to new blood vessels that originate from pre-existing vascular structures. Corneal neovascularization which can lead to compromised visual acuity occurs in a wide variety of corneal pathologies.
Sepehr Feizi, Amir A. Azari, Sharareh Safapour   +2 more
doaj   +3 more sources

Corneal melting following intrastromal injection of bevacizumab for corneal neovascularization

Oman Journal of Ophthalmology
The aim is to report corneal melting following intrastromal injection of antivascular endothelial growth factor (anti-VEGF), bevacizumab, for pre-existing corneal neovascularization.
Muna Salim Al-Ruhaili, Haitham Hilal Al-Mahrouqi   +1 more
doaj   +2 more sources

Assessment of Corneal Angiography Filling Patterns in Corneal Neovascularization. [PDF]

J Clin Med, 2023
The purpose of the paper is to describe vascular filling patterns in corneal neovascularization (CoNV) and evaluate the effect of corneal lesion location, CoNV surface area and multi-quadrant CoNV involvement on the filling pattern. It is a retrospective study of patients who were investigated for CoNV using fluorescein angiography (FA) or indocyanine ...
Pagano L, Shah H, Gadhvi K, Ahmad M, Menassa N, Coco G, Kaye S, Romano V.   +7 more
europepmc   +4 more sources

Novel artemisinin derivative P31 inhibits VEGF-induced corneal neovascularization through AKT and ERK1/2 pathways [PDF]

Heliyon
Corneal neovascularization (CoNV)is a major cause of blindness in many ocular diseases. Substantial evidence indicates that vascular endothelial growth factor (VEGF) plays an important role in the pathogenesis of corneal neovascularization.
Wen Ding, Yingxue Su, Jianshan Mo, Danyuan Sun, Chen Cao, Xiaolei Zhang, Yandong Wang   +6 more
doaj   +2 more sources

Shark Cartilage-Derived Anti-Angiogenic Peptide Inhibits Corneal Neovascularization [PDF]

Bioengineering
Corneal neovascularization is a significant cause of vision loss, often resulting in corneal clouding and chronic inflammation. Shark cartilage is widely recognized as a significant natural source of anti-angiogenic compounds.
Yunxian Li, Aoke Chen, An Hong, Sheng Xiong, Xiaojia Chen, Qiuling Xie   +5 more
doaj   +2 more sources

Challenge of Corneal Ulcer Healing: A Novel Conceptual Framework, the “Triad” of Corneal Ulcer Healing/Corneal Neovascularization/Intraocular Pressure, and Avascular Tendon Healing, for Evaluation of Corneal Ulcer Therapy, Therapy of Neovascularization, Glaucoma Therapy, and Pentadecapeptide BPC 157 Efficacy [PDF]

Pharmaceuticals
To better address the challenge of corneal ulcer healing, with already available standard agents, and those recently introduced, such as stable gastric pentadecapeptide BPC 157, we introduced a novel conceptual framework—the “triad” of corneal ulcer ...
Sanja Masnec, Antonio Kokot, Tamara Kralj, Mirna Zlatar, Kristina Loncaric, Marko Sablic, Miro Kalauz, Iva Beslic, Katarina Oroz, Bozana Mrvelj, Lidija Beketic Oreskovic, Ivana Oreskovic, Sanja Strbe, Borna Staresinic, Goran Slivsek, Alenka Boban Blagaic, Sven Seiwerth, Anita Skrtic, Predrag Sikiric   +18 more
doaj   +2 more sources

Aganirsen as a Therapeutic Alternative for Modulating Corneal Neovascularization: A Real-World Case Series Study [PDF]

Clinical Ophthalmology
Salvador García-Delpech,1 Sara Fathi Nieto,2 Ana Hervás Ontiveros,2,3 Patricia Udaondo,1,2 Damian Garcia-Teillard1,4 1Aiken Ophthalmological Clinic and Aiken Foundation, Valencia, Spain; 2Department of Ophthalmology, Hospital Universitario Y Politécnico ...
García-Delpech S, Fathi Nieto S, Hervás Ontiveros A, Udaondo P, Garcia-Teillard D   +4 more
doaj   +2 more sources

Genome Editing VEGFA Prevents Corneal Neovascularization In Vivo [PDF]

Advanced Science
Corneal neovascularization (CNV) is a common clinical finding seen in a range of eye diseases. Current therapeutic approaches to treat corneal angiogenesis, in which vascular endothelial growth factor (VEGF) A plays a central role, can cause a variety of
Zhenhai Zeng, Siheng Li, Xiuhong Ye, Yiran Wang, Qinmei Wang, Zhongxing Chen, Ziqian Wang, Jun Zhang, Qing Wang, Lu Chen, Shuangzhe Zhang, Zhilin Zou, Meimin Lin, Xinyi Chen, Guoli Zhao, Colm McAlinden, Hetian Lei, Xingtao Zhou, Jinhai Huang   +18 more
doaj   +2 more sources

Studying the effect of intrastromal anti-vascular endothelial growth factor injections on corneal neovascularization using optical coherence tomography angiography

Journal of the Egyptian Ophthalmological Society, 2023
Purpose To evaluate the effect of intrastromal injection of anti-vascular endothelial growth factor (Anti-VEGF) on corneal neovascularization using spectral domain Optical coherence tomography angiography imaging (OCTA).
Hussein Mohamed Sherif Ahmed Ayoub, Amr Saleh Mousa, Momen Mahmoud Hamdi, Rasha Mohamed Mousa, Mo′mena Ahmad A Awad-Allah   +4 more
doaj   +1 more source

Topically administered bevacizumab had longer standing anti-angiogenic effect than subconjunctivally injected bevacizumab in rat corneal neovacularization [PDF]

International Journal of Ophthalmology, 2013
AIM: To compare the effect of topically administered and subconjunctivally injected bevacizumab on experimental corneal neovascularization in rats for two weeks after treatment.METHODS: Twenty-eight Sprague-Dawley rats were divided into four groups of 7 ...
Jae Yong Kim, Dong Yoon Kim, Eun-Soon Kim, Myoung Joon Kim, Hungwon Tchah   +4 more
doaj   +1 more source