Results 11 to 20 of about 15,673 (182)

AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model

Cell Communication and Signaling, 2022
Background Apoptosis signal-regulating kinase 1-interacting protein 1 (AIP1) participates in inflammatory neovascularization induction. NADPH oxidase 4 (NOX4) produces reactive oxygen species (ROS), leading to an imbalance in nucleotide-binding ...
Qingyu Li, Xia Hua, Liangpin Li, Xueyan Zhou, Ye Tian, Yang Deng, Min Zhang, Xiaoyong Yuan, Wei Chi   +8 more
doaj   +1 more source

Regression of corneal opacity and neovascularization in Stevens-Johnson syndrome and Toxic Epidermal Necrolysis with the use of prosthetic replacement of the ocular surface ecosystem (PROSE) treatment

American Journal of Ophthalmology Case Reports, 2022
Purpose: To report two cases demonstrating the regression of corneal neovascularization and clearing of corneal opacification in patients with Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) undergoing prosthetic replacement of the ...
Jennifer Liao, OD, Bita Asghari, OD, Karen G. Carrasquillo, OD, PhD   +2 more
doaj   +1 more source

The effect of collagen-chitosan-natrium hyaluronate composite on neovascularization as angiogenesis reaction in rabbit corneal stroma wound (Experimental Study on Oryctolagus cuniculus) [PDF]

Annals of Mechnikov's Institute, 2021
Background: The inflammatory process in the healing of corneal wounds can lead to cicatricial tissue resulting in cloudiness, and blood vessels in the corneal tissue cause visual disturbances to blindness. Keratoplasty is the primary therapeutic modality
Arantrinita, Reni Prastyani, Prihartini Widiyanti   +2 more
doaj   +3 more sources

Monolith/Hydrogel composites as triamcinolone acetonide carriers for curing corneal neovascularization in mice by inhibiting the fibrinolytic system

Drug Delivery, 2022
Corneal neovascularization is a serious corneal pathological change caused by various factors. The drug delivery system is of great significance for the effective treatment of corneal neovascularization.
Cixin Huang, Xia Qi, Huilin Chen, Wei Chao, Xiaolin Qi, Hongwei Wang, Hua Gao   +6 more
doaj   +1 more source

Clickable corneal neovascularization therapy with ROS-responsive polydopamine silica nanoparticles loaded with fenofibrate

Materials & Design, 2023
Corneal neovascularization is a severe eye disease that is often associated with an inflammatory cycle and increased oxidative stress. Excessive reactive oxygen species can cause harmful changes in the corneal epithelium and lead to vicious inflammatory ...
Kai Fan, Lixue Yu, Yuehuang Wu, Lan Zheng, Xiuqin Yang, Jingwei Lin, Mengyuan Wang, Yingyue Ye, Ruimiao Lin, Quancheng Chen, Zeyu Liu, Yuhua Xue, Jingjing Xie, Cheng Li   +13 more
doaj   +1 more source

Three kinds of corneal host cells contribute differently to corneal neovascularizationResearch in context

EBioMedicine, 2019
Background: Corneal neovascularization (angiogenesis and lymphangiogenesis) compromises corneal transparency and transplant survival, however, the molecular mechanisms of corneal host epithelial and stromal cells in neovascularization have not yet been ...
Haiyang Yu, Liyao Sun, Jing Cui, Yan Li, Yu Yan, Xi Wei, Chao Wang, Fanqian Song, Wentong Jiang, Yifan Liu, Hongyan Ge, Hua Qian, Xiaoguang Li, Xianling Tang, Ping Liu   +14 more
doaj   +1 more source

Treatment of corneal neovascularization with topical aflibercept in a case of exposure keratopathy following cerebellar astrocytoma surgery

Indian Journal of Ophthalmology, 2019
In this report, we report the case of a 7-year-old boy with corneal neovascularization due to exposure keratopathy following cerebellar astrocytoma surgery.
Sibel Aksoy
doaj   +1 more source

Human tears reveal insights into corneal neovascularization. [PDF]

PLoS ONE, 2012
Corneal neovascularization results from the encroachment of blood vessels from the surrounding conjunctiva onto the normally avascular cornea. The aim of this study is to identify factors in human tears that are involved in development and/or maintenance
Nadia Zakaria, Sigi Van Grasdorff, Kristien Wouters, Jos Rozema, Carina Koppen, Eva Lion, Nathalie Cools, Zwi Berneman, Marie-José Tassignon   +8 more
doaj   +1 more source

Research on mouse model of grade II corneal alkali burn [PDF]

International Journal of Ophthalmology, 2016
AIM: To choose appropriate concentration of sodium hydroxide (NaOH) solution to establish a stable and consistent corneal alkali burn mouse model in grade II.
Jun-Qiang Bai, Hai-Feng Qin, Shi-Hong Zhao   +2 more
doaj   +1 more source

Subconjunctival bevacizumab for corneal neovascularization [PDF]

Acta Ophthalmologica, 2010
Acta Ophthalmol. 2010: 88: 868–871Abstract.Purpose:  This work aimed to study and evaluate the effect of subconjunctival bevacizumab injection in patients with corneal neovascularization (CNV) resulting from different ocular surface disorders.Methods:  Ten eyes with CNV caused by different ocular surface disorders were studied.
Ahmed A, Zaki, Samar F, Farid
openaire   +2 more sources