Results 51 to 60 of about 19,859 (195)

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

Environmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min, Seunghee Oh, Min Seong Jang, Kang‐Hyun Han   +3 more
wiley   +1 more source

Fania (Fanny) Kaplan and the attempted assassination of Vladimir Lenin: Ophthalmologic considerations

Acta Ophthalmologica, EarlyView.
Abstract Purpose Fania (Fanny) Kaplan (1890–1918), who was reportedly visually impaired, confessed to the attempted assassination of Soviet leader Vladimir Lenin (1870–1924) in 1918 by shooting him with a pistol. The precise nature of her visual loss is unknown and raises doubts about whether she had sufficient visual function to perform the act ...
Stephen G. Schwartz, Christopher T. Leffler, Peter M. Allen, Andrzej Grzybowski   +3 more
wiley   +1 more source

Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2. [PDF]

PLoS ONE, 2015
To investigate the phenotype and predisposing factors of a granular corneal dystrophy type 2 transgenic mouse model.Human TGFBI cDNA with R124H mutation was used to make a transgenic mouse expressing human protein (TGFBIR124H mouse).
Katsuya Yamazoe, Satoru Yoshida, Miyuki Yasuda, Shin Hatou, Emi Inagaki, Yoko Ogawa, Kazuo Tsubota, Shigeto Shimmura   +7 more
doaj   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Dystrophia Smolandiensis is characterized by a novel NQO1 variant and a distinct phenotype from COL17A1‐associated epithelial recurrent erosion dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer, Kristina Lagerstedt‐Robinson, Daniel Nilsson, Cilla Söderhäll, Björn Hammar, Erik Björck   +5 more
wiley   +1 more source

A prospective randomised comparison of two different stenting sutures when using the Baerveldt 101–350 aqueous shunt – Lab transition to clinical process

Acta Ophthalmologica, EarlyView.
Abstract Purpose The Baerveldt glaucoma drainage implant (BGI 101–350) is one of the most effective treatment options for managing refractory glaucoma. To mitigate early hypotony in non‐valved implants, intraluminal occluding sutures (IOSs) are commonly used.
Evripidis Sykakis, Anastasia Tsiogka, Vasileios Selimis, Minas I. Aslanides, Athanasios Skouras, George Kenanakis, Ioannis M. Aslanides, Minas M. Stylianakis   +7 more
wiley   +1 more source

Childhood ocular safety after postnatal exposure to topical dexamethasone during retinopathy of prematurity screening

Acta Ophthalmologica, EarlyView.
Abstract Purpose Dexamethasone eye drops are being introduced off‐label to prevent progression of severe retinopathy of prematurity (ROP). We evaluated ophthalmologic outcomes in early childhood after postnatal topical dexamethasone exposure in pre‐term infants at a standardized follow‐up examination.
Mariya Petrishka‐Lozenska, Anders K. Nilsson, Ann Hellström, Pia Lundgren   +3 more
wiley   +1 more source

Human Corneal Stromal Stem Cell Treatment Reduces Established Opacities in Chronic Corneal Scarring

Cells
Corneal fibrosis, clinically referred to as corneal scarring, disrupts the normal architecture and transparency of the cornea and remains a major cause of visual impairment worldwide. Although corneal transplantation can restore vision, its effectiveness
Kira L. Lathrop, Julia T. Coelho, Christine Chandran, Syeda R. Ali, Moira L. Geary, Deepinder K. Dhaliwal, Vishal Jhanji, Mithun Santra, Gary H. F. Yam   +8 more
doaj   +1 more source

Corneal tattooing for esthetic purposes in patients with corneal opacities

Indian Journal of Ophthalmology, 2020
This study evaluated corneal tattooing for esthetic purposes in patients with corneal opacification.Eight eyes of eight patients were included in the study (four males and four females). Corneal tattooing was achieved by stromal puncture in five patients, femtosecond laser-assisted corneal tattooing in two patients, and femtosecond laser-assisted ...
ÇANKAYA, CEM, DOĞANAY, SELİM, Doganay, Derya   +2 more
openaire   +4 more sources

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

Acta Ophthalmologica, EarlyView.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič, Nataša Debeljak, Petra Hudler, Janez Smerkolj, Mojca Urbančič   +4 more
wiley   +1 more source