Results 61 to 70 of about 115,122 (194)

MCOA: A Comprehensive Multimodal Dataset for Advancing Deep Learning in Corneal Opacity Assessment

Scientific Data
Corneal opacity remains a major global cause of vision impairment. Its severity is typically assessed subjectively by clinicians using slit lamp examinations of the anterior segment.
Xinyu Ma, Jianxia Fang, Yaqi Wang, Zhichao Hu, Zhe Xu, Sha Zhu, Weijia Yan, Mengqi Chu, Jingwei Xu, Siting Sheng, Chujun Liu, Mingxuan Zhang, Ce Shi, Gangyong Jia, Wen Xu   +14 more
doaj   +1 more source

Dystrophia Smolandiensis is characterized by a novel NQO1 variant and a distinct phenotype from COL17A1‐associated epithelial recurrent erosion dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer, Kristina Lagerstedt‐Robinson, Daniel Nilsson, Cilla Söderhäll, Björn Hammar, Erik Björck   +5 more
wiley   +1 more source

Intracameral endoilluminator-assisted phacoemulsification surgery in patients with severe corneal opacity

, 2020
While phacoemulsification cataract surgery is a routine and safe procedure, clear visualization of the anterior segment is challenging in patients with corneal opacity.
Yuksel, ERDEM, Erdem Yuksel
core   +1 more source

A prospective randomised comparison of two different stenting sutures when using the Baerveldt 101–350 aqueous shunt – Lab transition to clinical process

Acta Ophthalmologica, EarlyView.
Abstract Purpose The Baerveldt glaucoma drainage implant (BGI 101–350) is one of the most effective treatment options for managing refractory glaucoma. To mitigate early hypotony in non‐valved implants, intraluminal occluding sutures (IOSs) are commonly used.
Evripidis Sykakis, Anastasia Tsiogka, Vasileios Selimis, Minas I. Aslanides, Athanasios Skouras, George Kenanakis, Ioannis M. Aslanides, Minas M. Stylianakis   +7 more
wiley   +1 more source

Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2. [PDF]

PLoS ONE, 2015
To investigate the phenotype and predisposing factors of a granular corneal dystrophy type 2 transgenic mouse model.Human TGFBI cDNA with R124H mutation was used to make a transgenic mouse expressing human protein (TGFBIR124H mouse).
Katsuya Yamazoe, Satoru Yoshida, Miyuki Yasuda, Shin Hatou, Emi Inagaki, Yoko Ogawa, Kazuo Tsubota, Shigeto Shimmura   +7 more
doaj   +1 more source

CONGENITAL CORNEAL OPACITIES

Russian Pediatric Ophthalmology, 2010
The article is dedicated to the clinical picture and diagnostics as well as the principles of management of pediatric patients with corneal opacity of various genesis including congenital malformations of the anterior section of the eye (posterior embryotoxon, Axenfeld anomaly, Rieger anomaly, Peters anomaly, corneal staphyloma, sclerocornea). Clinical
L A Katargina, A V Pleskova, A V Khvatova   +2 more
openaire   +1 more source

Childhood ocular safety after postnatal exposure to topical dexamethasone during retinopathy of prematurity screening

Acta Ophthalmologica, EarlyView.
Abstract Purpose Dexamethasone eye drops are being introduced off‐label to prevent progression of severe retinopathy of prematurity (ROP). We evaluated ophthalmologic outcomes in early childhood after postnatal topical dexamethasone exposure in pre‐term infants at a standardized follow‐up examination.
Mariya Petrishka‐Lozenska, Anders K. Nilsson, Ann Hellström, Pia Lundgren   +3 more
wiley   +1 more source

The higher-order aberrations (HOAs) based on corneal opacity grading in corneal dystrophies.

, 2016
There were no significant differences in HOAs among corneal opacity grade 1, 2 and 3 in GCD2 (all Ps > 0.05). In the MCD group, the HOAs in eyes with corneal opacity grade 3 were significantly larger than those of grade 2 (P = 0.018).
Yumi Okuyama (3044502), Yukari Yagi-Yaguchi (3044496), Takefumi Yamaguchi (345080), Yoshiyuki Satake (3044499), Jun Shimazaki (600554), Kazuo Tsubota (247512)   +5 more
core   +1 more source

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

Acta Ophthalmologica, EarlyView.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič, Nataša Debeljak, Petra Hudler, Janez Smerkolj, Mojca Urbančič   +4 more
wiley   +1 more source

A genetic and historical perspective on the origins of keratitis fugax hereditaria

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the genetic and genealogical background of keratitis fugax hereditaria (KFH), a periodic corneal disease caused by the heterozygous pathogenic variant c.61G>C in the NLRP3 gene. KFH is characterized by recurrent unilateral autoinflammatory attacks alternating between the eyes and permanent corneal opacities.
Annamari T. Immonen, Sara P. Luostarinen, Päivi Lahermo, Sabita Kawan, Kati Donner, Joseph D. Terwilliger, Michael P. Backlund, Joni A. Turunen   +7 more
wiley   +1 more source