Results 61 to 70 of about 21,333 (219)

Corneal transparency and scleral opacity arises from the nanoarchitecture of the constituent collagen fibrils. [PDF]

, 2022
While human scleral and corneal tissues possess similar structural morphology of long parallel cylindrical collagen fibrils, their optical characteristics are markedly different. Using pseudospectral time-domain (PSTD) simulations of Maxwell's equations,
Ranasinghesagara, Janaka C, Tseng, Snow H, Jeng, Yung-Ming, Li, Jia-Hao, Yang, Chih-Yao, Venugopalan, Vasan   +5 more
core   +1 more source

A Novel Slit Lamp‐Based System for 3D Ultrasound of the Eye

Journal of Ultrasound in Medicine, EarlyView.
Objectives This study aims to develop and evaluate a novel slit‐lamp‐based system to acquire 3‐dimensional (3D) ultrasound volumes using conventional ultrasound probes. Methods A slit‐lamp adapter was 3D printed and connected with a linear actuator and graphical user interface (GUI) system to control movement and create volumes of 2‐dimensional scans ...
Claire E. Malley, Joseph P. Miller, Boyan Pan, Josiah K. To, Jack O. Thomas, Steven Y. Chang, Jason Dagoon, William C. Tang, Parsa Riazi Esfahani, Andrew W. Browne   +9 more
wiley   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

Environmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min, Seunghee Oh, Min Seong Jang, Kang‐Hyun Han   +3 more
wiley   +1 more source

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

Acta Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova, Marceline N. Akieh‐Pirkanniemi, Arto Hartikainen, Hanna Arstila, Kai Kaarniranta, Lasse Leino   +5 more
wiley   +1 more source

Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2. [PDF]

PLoS ONE, 2015
To investigate the phenotype and predisposing factors of a granular corneal dystrophy type 2 transgenic mouse model.Human TGFBI cDNA with R124H mutation was used to make a transgenic mouse expressing human protein (TGFBIR124H mouse).
Katsuya Yamazoe, Satoru Yoshida, Miyuki Yasuda, Shin Hatou, Emi Inagaki, Yoko Ogawa, Kazuo Tsubota, Shigeto Shimmura   +7 more
doaj   +1 more source

Acute Bilateral Diffuse Corneal Opacity in a Child

, 2009
Purpose: To report a case of acute bilateral corneal opacity related to bacterial blepharoconjunctivitis. Methods: Interventional case report. An 18-month-old boy had bilateral red eyes with discharge and periorbital eczema.
WANG, TSUNG-JEN;HSIAO, CHENG-HSIANG;HU, FUNG-RONG;WANG, I-JONG;HOU, YU-CHIH, 王宗仁;蕭正祥;胡芳蓉;王一中;侯育致   +1 more
core   +1 more source

Occupational exposure to metal welding and cataract: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract Background Metal welding generates ultraviolet radiation (UVR) of cataractogenic wavelengths, and UVR emitted during welding has been associated with cataract formation, but results from prior studies are conflicting. Methods We conducted a systematic review and meta‐analysis of epidemiological studies addressing associations between ...
Jakob Bjerager, Esben Meulengracht Flachs, Martin Nissen Hermann, Jens Peter Ellekilde Bonde, Ingrid Sivesind Mehlum, Stinna Skaaby   +5 more
wiley   +1 more source

Corneal opacity evaluation of alkali burn injured corneas.

, 2015
(A-D) Corneal surface observation 3 days after injury in control, MSCs treatment, polysaccharide treatment and polysaccharide-MSCs combination (PM) groups, (E-H) Corneal surface observation 7 days after injury in various groups, (I-L) Corneal surface ...
Min Yu (120607), Chunbo Yang (706043), Yifeng Ke (706040), Xuan Cui (706042), Xun Liu (285130), Yixiang Wu (706041), Xiaorong Li (66719)   +6 more
core   +1 more source

Fania (Fanny) Kaplan and the attempted assassination of Vladimir Lenin: Ophthalmologic considerations

Acta Ophthalmologica, EarlyView.
Abstract Purpose Fania (Fanny) Kaplan (1890–1918), who was reportedly visually impaired, confessed to the attempted assassination of Soviet leader Vladimir Lenin (1870–1924) in 1918 by shooting him with a pistol. The precise nature of her visual loss is unknown and raises doubts about whether she had sufficient visual function to perform the act ...
Stephen G. Schwartz, Christopher T. Leffler, Peter M. Allen, Andrzej Grzybowski   +3 more
wiley   +1 more source