Results 61 to 70 of about 23,284 (269)

RHO-Associated Coiled-Coil-Containing Protein Kinase Inhibitors Significantly Modulate the Epithelial–Mesenchymal Transition Induced by TGF-β2 in the 2-D and 3-D Cultures of Human Corneal Stroma Fibroblasts

Biomedicines
Background/Objectives: The objective of the present study was to examine the unidentified effects that RHO-associated coiled-coil-containing protein kinase 1 and 2 antagonists exert on the transforming growth factor beta2-induced epithelial–mesenchymal ...
Araya Umetsu, Yosuke Ida, Tatsuya Sato, Megumi Higashide, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro, Megumi Watanabe   +7 more
doaj   +1 more source

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

Advanced Science, EarlyView.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu, Tonghe Yang, Yuan Geng, Huan Wu, Yangrui Huang, Te Zheng, Haodi Chen, Shurui Huang, Yi Cao, Jian Yang, Wentao Yan, Yikui Zhang, Wencan Wu   +12 more
wiley   +1 more source

Anterior-segment morphology and corneal biomechanical characteristics in pigmentary glaucoma [PDF]

, 2013
Annemarie Klingenstein, Marcus Kernt, Florian Seidensticker, Anselm Kampik, Christoph HirneissDepartment of Ophthalmology, University of Munich Hospital, Ludwig-Maximilians University, Munich, GermanyPurpose: The aim of the study reported here was to ...
Hirneiss C, Seidensticker F, Kernt M, Kampik A, Klingenstein A   +4 more
core  

The corneal volume and biomechanical corneal factors: Is there any correlation? [PDF]

, 2020
BACKGROUND: The aim of this study was to determine the correlation between corneal hysteresis (CH) and the corneal resistance factor (CRF), which are both novel methods of analyzing ocular rigidity/elasticity, and various corneal characteristics, mainly ...
Maria Sharepoor, Samira Hassanzadeh, Mohammad Reza Sedaghat, Mojtaba Abrishami   +3 more
core  

Effect of topical corneal anaesthesia on ocular response analyzer parameters: pilot study. [PDF]

, 2009
The effect of topical corneal anaesthesia on corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal compensated IOP (IOPcc) was measured by ocular response analyzer (ORA).Journal ...
Pourjavan, Sayeh, De Maertelaer, Viviane, Ehongo Bidime, Adèle   +2 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Corneal biomechanical properties during the menstrual cycle [PDF]

, 2011
Purpose: To determine if corneal biomechanical properties change during phases of the menstrual cycle. Methods: Twenty-five healthy women of reproductive age with no ocular pathology or systemic diseases were recruited.
Zerdeci N., Seymenoǧlu G., Baser E.F., Gülhan C.   +3 more
core   +1 more source

Relationship between Corneal Morphogeometrical Properties and Biomechanical Parameters Derived from Dynamic Bidirectional Air Applanation Measurement Procedure in Keratoconus

Diagnostics, 2020
The morphogeometric analysis of the corneal structure has become a clinically relevant diagnostic procedure in keratoconus (KC) as well as the in vivo evaluation of the corneal biomechanical properties.
Francisco Cavas, David Piñero, José S. Velázquez, Jorge Mira, Jorge L. Alió   +4 more
doaj   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Colocalization of corneal resistance factor GWAS loci with GTEx e/sQTLs [PDF]

Data files needed for running codes in https://github.com/xinyixinyijiang/CRF_GTExv8_KC Files: /crf/FINEMAP_credible_sets.tsv: Fine-mapping results for CRF GWAS Loci using FINEMAP. Souce: published in (Jiang et al, 2020) /dapg/*: Input files required for
Boutin, Thibaud, Vitart, Veronique, School of Population Health Sciences, MRC Human Genetics Unit, Jiang, Xinyi, School of Genetics and Cancer   +5 more
core   +1 more source