Results 71 to 80 of about 23,284 (269)

Corneal Biomechanical Properties in Patients With Arcus Senilis [PDF]

, 2016
Purpose:To compare the corneal biomechanical properties and intraocular pressure (IOP) levels in patients with and without arcus senilis (AS).Methods:Ocular response analyzer measurements were performed on the right eyes of 37 patients with AS (group 1 ...
KAYA, MAHMUT, GÜNENÇ, ÜZEYİR, ÖZTÜRK, ARİF TAYLAN, ARIKAN, GÜL, AYHAN, ZİYA   +4 more
core   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Corneal biomechanical changes and intraocular pressure in patients with thyroid orbitopathy [PDF]

International Journal of Ophthalmology, 2016
AIM: To determine the relevance of the objective parameters addressing the altered biomechanical properties of cornea for glaucoma monitoring in patients with mild or moderate thyroid associated orbitopathy (TAO), and in healthy individuals.
Zofia Pniakowska, Anna Klysik, Roman Gos, Piotr Jurowski   +3 more
doaj   +1 more source

Evaluation of Corneal Biomechanical Changes After Collagen Crosslinking in Patients with Progressive Keratoconus by Ocular Response Analyzer [PDF]

, 2018
Objectives:To evaluate corneal biomechanics before and after collagen crosslinking (CXL) in patients with progressive keratoconus.Materials and Methods:In this prospective study, CXL was performed under topical anesthesia after removal of the epithelium (
Ferda Çiftçi, Sahan, Berna, Ciftci, Ferda, Kucumen, Raciha Beril, Berna Şahan, Raciha Beril Küçümen, YILDIRIM, CANAN ASLI, Canan Aslı Yıldırım   +7 more
core   +1 more source

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source

Corneal biomechanics in normal Saudi individuals [PDF]

, 2016
PurposeThe aim of this study was to determine and relate corneal biomechanical metrics with demographic, tomographic and refractive data in healthy Saudi people.DesignProspective, cross-sectional, observational study.ParticipantsThe study included 215 ...
Al-Shamlan, Fatimah, Yassin, Sanaa A., Al-Jindan, Mohanna, Sanaa A. Yassin, Khalid Al-Arfaj, Walaa Al-Dairi, Fatimah Al-Shamlan, Al-Dairi, Walaa, Al-Arfaj, Khalid, Mohanna Al-Jindan   +9 more
core   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Use of biomechanical waveform analysis to establish intraocular pressure and biomechanical properties of the cornea in adult myopic Egyptian patients

Journal of the Egyptian Ophthalmological Society, 2015
Aim The aim of this study was to determine intraocular pressure (IOP) and corneal biomechanical properties in myopic patients in Suez Canal area in Egypt. Materials and methods A total of 350 eyes of myopic patients (n = 179, age = 29.4 ± 8.9 years) with
Amr Abdel-Fattah Gab-Alla
doaj   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

Natural Aging of Biomaterials in Ambient and Physiological Environments

Advanced NanoBiomed Research, EarlyView.
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley   +1 more source