Recommendations for the management of MPS IVA: systematic evidence- and consensus-based guidance. [PDF]
IntroductionMucopolysaccharidosis (MPS) IVA or Morquio A syndrome is an autosomal recessive lysosomal storage disorder (LSD) caused by deficiency of the N-acetylgalactosamine-6-sulfatase (GALNS) enzyme, which impairs lysosomal degradation of keratan ...
Akyol, Mehmet Umut+30 more
core +2 more sources
The Immune Response to Herpes Simplex Virus Type 1 Infection in Susceptible Mice is a Major Cause of CNS Pathology Resulting in Fatal Encephalitis [PDF]
This study was undertaken to investigate possible immune mechanisms in fatal HSV-1 encephalitis (HSE) after HSV-1 corneal inoculation. Susceptible 129S6 (129) but not resistant C57BL/6 (B6) mice developed intense focal inflammatory brainstem lesions of ...
Brown, Jeffrey+10 more
core +2 more sources
Limbal stem cell transplantation: clinical results, limits, and perspectives [PDF]
Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and in an invasion of the cornea by the conjunctival epithelium.
Bruscolini, Alice+3 more
core +1 more source
Bioprinted Membranes for Corneal Tissue Engineering: A Review
Corneal transplantation is considered a convenient strategy for various types of corneal disease needs. Even though it has been applied as a suitable solution for most corneal disorders, patients still face several issues due to a lack of healthy donor ...
Amin Orash Mahmoud Salehi+7 more
doaj +1 more source
Amniotic Membrane Transplantation an Experience of a Locally Prepared Tissue
Nada Al-Yousuf,1,2 Hasan Alsetri,3 Eman Farid,4,5 Sara M George4 1Department of Ophthalmology, King Abdullah Medical City, Manama, Kingdom of Bahrain; 2Department of Surgery, College of Medicine, Manama, Kingdom of Bahrain; 3Department of Chemistry and ...
Al-Yousuf N+3 more
doaj
Corneal dystrophies are a group of non-inflammatory inherited disorders of the cornea. This review considers treatment options for epithelial-stromal and stromal corneal dystrophies: namely Reis–Bücklers, Thiel–Behnke, lattice, Avellino, granular ...
Zahra Ashena+2 more
doaj +1 more source
Deep Learning Based Unsupervised and Semi-supervised Classification for Keratoconus [PDF]
The transparent cornea is the window of the eye, facilitating the entry of light rays and controlling focusing the movement of the light within the eye. The cornea is critical, contributing to 75% of the refractive power of the eye. Keratoconus is a progressive and multifactorial corneal degenerative disease affecting 1 in 2000 individuals worldwide ...
arxiv
Minocycline is cytoprotective in human corneal endothelial cells and induces anti-apoptotic B-cell CLL/lymphoma 2 (Bcl-2) and X-linked inhibitor of apoptosis (XIAP) [PDF]
Introduction Loss of corneal endothelial cells (CECs) is one major factor limiting transplant clarity and survival after keratoplasty. Amongst other factors, apoptosis due to cellular stress is responsible for these problems.
Hirneiß, Christoph+3 more
core +3 more sources
Crosslinking in the complex treatment of corneal ulceration and corneal grafting
Purpose: to study the impact of crosslinking (CL) on the healing of corneal ulcers of various etiologies. Materials and methods. Treatment results of 15 patients with corneal and transplant ulcers by CL and its combination with other surgical ...
E. V. Chentsova+3 more
doaj +1 more source
Eye Lesions in Patients After One Year of Kidney Transplantation
Nguyen Le Trung,1,2 Pham Quoc Toan,3 Nguyen Kien Trung,4 Vu Anh Tuan,1 Nguyen Thu Huyen5 1Vietnam Department of Ophthalmology, Hanoi Medical University, Hanoi, Vietnam; 2Vietnam Department of Ophthalmology, Military Hospital 103, Hanoi, Vietnam; 3Vietnam
Trung NL+4 more
doaj