Results 81 to 90 of about 28,419 (324)

Overexpression of MMPs in Corneas Requiring Penetrating and Deep Anterior Lamellar Keratoplasty. [PDF]

open access: yes, 2019
PurposeMatrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases involved in wound healing processes, including neovascularization and fibrosis. We assessed MMP protein expression levels in diseased corneas of patients requiring
Chan, Matilda F   +5 more
core  

Immune- and nonimmune-compartment-specific interferon responses are critical determinants of herpes simplex virus-induced generalized infections and acute liver failure [PDF]

open access: yes, 2016
The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis.
Leib, David A   +3 more
core   +3 more sources

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

Corneal Dermoid [PDF]

open access: yes, 2011
A 20 years old boy presented with left corneal mass. The mass involved entire cornea extending to the sclera. The mass had a skin like surface and protruded outside the palpebral aperture.
Achar, A, Hegde, S, Kadri, R, Kudva, AA
core  

A machine learning approach to explore predictors of graft detachment following posterior lamellar keratoplasty: a nationwide registry study [PDF]

open access: yes, 2022
Machine learning can be used to explore the complex multifactorial patterns underlying postsurgical graft detachment after endothelial corneal transplantation surgery and to evaluate the marginal effect of various practice pattern modulations.
The Netherlands Corneal Transplant Network (NCTN)
core  

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

New Perspectives on Polysaccharides From Gracilaria and Gracilariopsis (Rhodophyta) and Their Potential Applications in Future Industries

open access: yesFood Frontiers, EarlyView.
1. Gracilaria is abundantly available red seaweed that has been used as a traditional medicine and food for years and is rich in nutritional value. 2. Gracilaria polysaccharides are sulfated and have been reported to possess various beneficial biological activities and are widely used in food packaging, food formulation, cosmeceutical products, and ...
Amanda Tresiliana Mulio   +4 more
wiley   +1 more source

Efficacy of combined use of anti-VEGF (Aflibercept) and lasercoagulation for corneal neovascularisation before keratoplasty

open access: yesКлиническая практика, 2018
It is known that both pre- and postkeratoplasty neovascularization of the cornea can significantly increase the risk of graft rejection reaction. The article presents preliminary results of the use of a VEGF inhibitor combined with laser coagulation ...
V. R. Mamikonyan   +4 more
doaj   +1 more source

Predicting the outcome of renal transplantation [PDF]

open access: yes, 2012
ObjectiveRenal transplantation has dramatically improved the survival rate of hemodialysis patients. However, with a growing proportion of marginal organs and improved immunosuppression, it is necessary to verify that the established allocation system ...
Arnold, S.   +4 more
core   +1 more source

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