Results 101 to 110 of about 1,194,426 (349)

Electrospun Poly (Glycerol Sebacate) (PGS) Membranes for Corneal Tissue Engineering

Macromolecular Materials and Engineering, EarlyView.
Fibrous PGS membranes that are composed of homogenous fibers are fabricated by electrospinning. Durability and permeability of the membranes closely resemble the natural cornea. Thereby, successfully supporting the proliferation of human corneal epithelial cells (HCEC) and human corneal endothelial cells (HCEndC).
Sumeyye Narin, Sevilay Burcu Sahin, Ebru Demir, Sibel Cetinel   +3 more
wiley   +1 more source

Tissue engineering a fetal membrane [PDF]

, 2011
The aim of this study was to construct an artificial fetal membrane (FM) by combination of human amniotic epithelial stem cells (hAESCs) and a mechanically enhanced collagen scaffold containing encapsulated human amniotic stromal fibroblasts (hASFs ...
Adam M. Squires, Anna L. David, Bipasha Chowdhury, Che John Connon, Connon C.J., Grinnell F., Ian William Hamley, Jones R.R., Kirkham S.M., Roanne Razalia Jones, Shengli Mi, Trinkaus R.V.   +11 more
core   +1 more source

Current Application Status and Innovative Development of Surgical Robot

Med Research, EarlyView.
Advantage, Challenge and Innovation of surgical robots. ABSTRACT Surgery has undergone a revolutionary development since the innovations in anesthesiology, aseptic techniques, and antibiotics. The use of modern techniques, especially minimally invasive techniques, has led to a new era of microsurgery and reduced patient trauma.
Aimin Jiang, Zhao Tang, Hanzhong Zhang, Jinxin Li, Jialin Meng, Ying Liu, Yu Fang, Juan Lu, Xu Zhang, Le Qu, Anqi Lin, Linhui Wang   +11 more
wiley   +1 more source

Post-operative complications of penetrating corneal keratoplasty in patients with anterior segment toxic syndrome secondary to cataract surgery

ABCS Health Sciences, 2020
Introduction: Toxic Anterior Segment Syndrome (TASS) after cataract surgery may cause severe corneal decompensation that compromises corneal transparency and may require penetrating corneal keratoplasty to improve visual acuity.
Elen Nishimoto Nishi, Vagner Loduca Lima, Glaucia Luciano da Veiga, Luiz Antonio de Brito Martins   +3 more
doaj   +1 more source

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

Med Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang, Yanyun Pang, Peijia Zhu, Zhengdong Zhang, Sen Guo, Zhijian Wei, Wenzhao Wang, Bin Ning   +7 more
wiley   +1 more source

Incidental Identification of Potentially Affected Individuals Through Expanded Carrier Screening During Preconception or Early Pregnancy

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Expanded carrier screening (ECS) is used to assess the reproductive probability of having an offspring affected by an autosomal recessive or X‐linked recessive genetic disorder. Rarely, a presumably healthy individual may be identified to carry variants that could influence their health.
Yan Lü, Jiazhen Chang, Yulin Jiang, Xiya Zhou, Na Hao, Yiqing Yu, Mengmeng Li, Kaili Yin, Xueting Yang, Qingwei Qi   +9 more
wiley   +1 more source

Case Report: Simultaneous penetrating keratoplasty with autologous simple limbal epithelial transplantation as an alternative to keratoprosthesis [version 2; peer review: 2 approved]

F1000Research, 2023
Introduction and importance: This case report highlights the multidisciplinary approach required to achieve successful anatomical and functional outcomes, in an eye with total limbal stem cell deficiency (LSCD) associated with underlying corneal scarring
Swati Singh, Swapna S. Shanbhag, Supriya Sharma   +2 more
doaj  

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Modified Gunderson Conjunctival Flap Combined with an Oral Mucosal Graft to Treat an Intractable Corneal Lysis after Chemical Burn: A Case Report

Kaohsiung Journal of Medical Sciences, 2006
Following a severe chemical injury, persistent corneal melting presents as a threatening condition for loss of vision or the eyeball itself. Keratoplasty (both lamellar and penetrating) and amniotic membrane transplantation have been the usual modes of ...
Kai-Chun Cheng, Cheng-Hsien Chang
doaj   +1 more source

Cryomicroneedle Arrays for Biotherapeutics Delivery

Small Science, EarlyView.
CryoMNs for biotherapeutic delivery to treat various diseases. CryoMNs: cryomicroneedles. Biotherapy offers a promising approach for treating a variety of diseases. However, the lack of advanced delivery systems remains a significant barrier to improve the efficacy, safety, and cost‐effectiveness of biotherapeutics.
Chunli Yang, Li Zhang, Angxi Zhou, Siyi Wang, Ya Ren, Maya Xiang, Run Tian, Yang Yu, Rong Li, Maling Gou   +9 more
wiley   +1 more source