Results 111 to 120 of about 513,149 (230)

High Doses of N‐Acetyl‐P‐Aminophenol Cause Acute Changes in Electroencephalographic and Electrocardiographic Activities in Wistar Rats

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT N‐acetyl‐p‐aminophenol (APAP), or acetaminophen, is the most prescribed analgesic and antipyretic, even used in association with other drugs. Because it is easily bought in drugstores, much evidence about its toxic effects is known due to high doses or continuous use, which can lead to death in cases of intoxication.
Alex Luiz Menezes da Silva, Luiz Gustavo dos Reis de Freitas, Akira Otake Hamoy, Clarissa Araujo da Paz, Luan Oliveira Ferreira, Esther Padilha da Silveira, Maria Klara Otake Hamoy, Nilton Akio Muto, Dielly Catrina Favacho Lopes, Moisés Hamoy   +9 more
wiley   +1 more source

E-Selectin Mediates Immune Cell Trafficking in Corneal Transplantation

, 2018
Background Immune rejection continues to threaten all tissue transplants. Here we sought to determine whether P- and E- selectin mediate T cell recruitment in corneal transplantation and whether their blockade can reduce T cell graft infiltration and ...
Hua, Jing, Ding, Julia, Dana, Reza, Omoto, Masahiro, Hamrah, Pedram, Chauhan, Sunil, Dohlman, Thomas H., Di Zazzo, Antonio   +7 more
core   +1 more source

Epidermal necrolysis sequelae: A cohort study on prevalence and risk factors

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 11, Page 1850-1858, November 2026.
Long‐term sequelae after epidermal necrolysis are frequent, multiple and often severe. Cutaneous, ocular and psychological complications are more frequent, with significant socioeconomic impact. Cluster analysis identifies distinct patient profiles, highlighting the need for personalized multidisciplinary follow‐up.
Thanh Vy Nguyen, Thomas Bettuzzi, Karim Zaghbib, Julie Gueudry, Audrey Colin, Kmar Bel Hareth, Narimane Terkmane, Emilie Sbidian, Nicolas de Prost, Saskia Ingen‐Housz‐Oro   +9 more
wiley   +1 more source

Corneal Xenotransplantation: Lessons From Allograft Immunobiology and Emerging Translational Strategies

Xenotransplantation, Volume 33, Issue 6, November/December 2026.
ABSTRACT Corneal transplantation is an effective sight‐restoring procedure, yet its global impact remains constrained by limited and uneven access to human donor tissue and by immune‐mediated graft failure, particularly in high‐risk recipients. Xenotransplantation offers a potentially scalable alternative, but successful clinical translation requires ...
Ansu A. John, Ellen H. Koo
wiley   +1 more source

CORNEAL TRANSPLANTATION IN CHILDREN

Collegium antropologicum, 2000
Purpose: To describe the surgical success rate and visual results of penetrating keratoplasty in a series of young children. Methods: Retrospective study of children aged 16 years and younger (range 6-16 years) who underwent corneal transplantation between1994 and 1999 at our Department.
Dekaris, Iva, Mravičić, Ivana, Gabrić, Nikica, Karaman, Željka   +3 more
openaire   +3 more sources

Transplantation of cultured corneal endothelial cells: Towards clinical application [PDF]

, 2020
Corneal transplantation still represents the elected method for the treatment of corneal endothelial pathologies. However, the worldwide shortage of donor corneas induced the exploration of approaches to use the donor tissue more efficiently or to be ...
Spinozzi D.
core  

Maintained transparency of preserved cornea after penetrating keratoplasty for fungal keratitis: A case report

American Journal of Ophthalmology Case Reports
Purpose: This report presents a case of fungal keratitis treated with penetrating keratoplasty using a cryopreserved cornea, highlighting the successful maintenance of corneal transparency post infection resolution.
Kazuki Yashiro, Takashi Ono, Yukako Taketani, Mikiko Kimakura, Tetsuya Toyono, Makoto Aihara, Takashi Miyai   +6 more
doaj   +1 more source

Waiting list distribution with indications for corneal transplantation.

, 2018
This figure shows the distribution of the corneal graft waiting list with indications for corneal transplantation (Fuchs' dystrophy, keratoconus, bullous keratopathy, trauma, rejection, and others) from 2004 to 2015 in 735 cases. The most common surgical
Tobias Röck (5447411), Karl U. Bartz-Schmidt (167658), Daniel Röck (5447414)   +2 more
core   +1 more source

In Vivo Expansion of Regulatory T Cells by Low-Dose Interleukin-2 Treatment Increases Allograft Survival in Corneal Transplantation

, 2018
Background Corneal allograft survival dramatically decreases in hosts with inflamed or vascularized recipient beds. We have previously shown that in rejected corneal allografts regulatory T cells (Tregs) demonstrate diminished Foxp3 expression and ...
Tahvildari, Maryam, Kaye, Abigail E., Dana, Reza, Chen, Yihe, Omoto, Masahiro, Emami-Naeini, Parisa, Chauhan, Sunil, Dohlman, Thomas H., Inomata, Takenori   +8 more
core   +1 more source

UV light-mediated corneal crosslinking as (lymph)angioregressive pretreatment to promote graft survival after subsequent high-risk corneal transplantation (CrossCornealVision): protocol for a multicenter, randomized controlled trial

Trials
Background Good vision highly depends on the transparency of the cornea, which is the “windscreen” of the eye. In fact, corneal blindness due to transparency loss is the second most common cause of blindness worldwide, and corneal transplantation is the ...
Johanna Wiedemann, Deniz Hos, Endrik Limburg, Ulrike Zettelmeyer, Petra Schiller, Jeremy Franklin, Björn Bachmann, Daniel Böhringer, Tina Dietrich-Ntoukas, Thomas A. Fuchsluger, Gerd Geerling, Stefan J. Lang, Wolfgang Johann Mayer, Siegfried Priglinger, Thomas Reinhard, Berthold Seitz, Claus Cursiefen   +16 more
doaj   +1 more source