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Pharmacotherapy of corneal transplantation [PDF]
Corneal transplantation is a surgical procedure in which damaged or diseased cornea is replaced by cadaveric corneal tissue. It is the most common form of solid-tissue transplantation in humans but its pharmacotherapy (in relation to graft rejection) has changed little for several decades.
Ziaei, Mohammed +2 more
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Current Opinion In Ophthalmology, 1992
Corneal transplantation is the most widely practiced form of clinical transplantation. This was made possible by the development of donor handling and preservation techniques, such as cooled culture media and organ-culture systems, that guarantee a sufficient supply of donor tissue.
F, Bigar, C P, Herbort
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Corneal transplantation is the most widely practiced form of clinical transplantation. This was made possible by the development of donor handling and preservation techniques, such as cooled culture media and organ-culture systems, that guarantee a sufficient supply of donor tissue.
F, Bigar, C P, Herbort
openaire +2 more sources
Archives of Ophthalmology, 1950
IN AN earlier report 1 on the visual and cosmetic results of corneal transplantation, the unfortunate effect of the glaring publicity attending this operation was discussed. It was suggested that this tidal wave of optimism has blinded both the layman and the physician to the true facts about corneal transplantation.
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IN AN earlier report 1 on the visual and cosmetic results of corneal transplantation, the unfortunate effect of the glaring publicity attending this operation was discussed. It was suggested that this tidal wave of optimism has blinded both the layman and the physician to the true facts about corneal transplantation.
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Corneal ulcers in corneal transplants
Current Eye Research, 1981Twenty-nine eyes, representing an infection rate of 4.9%, developed corneal ulcers following corneal transplant surgery; 26 with available data are presented. All occurred in the graft or at the wound margin. The median postoperative time to ulcer development was 5.5 months. All eyes were on topical steroids when the ulcer developed.
A W, Tuberville, T O, Wood
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Corneal Transplantation in an Infant with Corneal Dermoid
American Journal of Ophthalmology, 1982A 1-month-old infant had a protuberant congenital corneal dermoid that extended into the anterior chamber. The dermoid was excised in two stages. A 12-mm lamellar keratectomy was followed three months later by a smaller (8-mm) penetrating keratoplasty.
G W, Zaidman, B, Johnson, S I, Brown
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The Immunobiology of Corneal Transplantation
Transplantation, 2007Corneal allotransplantation is highly successful in the short term, but much less successful in the longer term. Many corneal grafts in recipients with corneal neovascularization or the sequelae of ocular inflammation undergo irreversible rejection, despite topical immunosuppression with glucocorticosteroids. Sensitization to cornea-derived alloantigen
Williams, Keryn Anne +1 more
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Corneal Endothelial Transplantation
Ophthalmology, 1980Patients with visually significant corneal edema, secondary to endothelial dysfunction, before the development of scaring or vascularization, need only have the corneal endothelium replaced to restore corneal clarity. This fact, plus the lack of consistently available donor material, prompted us to evaluate tissue cultured corneal endothelim (TCCE) as ...
J P, McCulley +2 more
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Targeted corneal transplantation
Current Opinion in Ophthalmology, 2012Corneal transplantation surgery has moved from an era of conventional penetrating keratoplasty to selective replacement of the diseased corneal layer with complementary healthy donor corneal tissue. Anterior lamellar transplantation surgeries do not involve replacement of corneal endothelium, consequently eliminating the occurrence of endothelial ...
Vishal, Jhanji +4 more
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2022
Corneal transplantation is the most common form of organ transplantation worldwide. Transplant survival depends on various factors, many of which are not fully understood. Due to the existence of many genetically defined strains, mouse models of corneal transplantation are most commonly used.
Peng, Chen +5 more
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Corneal transplantation is the most common form of organ transplantation worldwide. Transplant survival depends on various factors, many of which are not fully understood. Due to the existence of many genetically defined strains, mouse models of corneal transplantation are most commonly used.
Peng, Chen +5 more
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Corneal Transplantation and Glaucoma
Seminars in Ophthalmology, 2014Glaucoma is the leading cause of irreversible vision loss post-keratoplasty and an important cause of graft failure. With newer techniques, such as lamellar, endothelial, and laser-assisted keratoplasty as well as keratoprosthesis gaining popularity, clinicians will need to consider the incidence, risks, evaluation, and management of glaucoma for each ...
Ramez I, Haddadin, James, Chodosh
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