Gaucher disease, state of the art and perspectives
Abstract Knowledge about Gaucher disease (GD), considered a model for rare diseases, has considerably increased since its discovery. The pathophysiology of this lysosomal disorder is better known, and specific therapies that can control many aspects of the disease have been developed, particularly for the most common form, Type 1 GD.
Fabrice Camou, Marc G. Berger
wiley +1 more source
Immunomodulation of salivary gland function due to cancer therapy
Abstract Functional salivary glands (SG) are essential for maintaining oral health, and salivary dysfunction is a persistent major clinical challenge. Several cancer therapies also have off‐target effects leading to SG dysfunction. Recent advances highlight the role of SG immune populations in homeostasis, dysfunction and gland regeneration.
Ana C. Costa‐da‐Silva+3 more
wiley +1 more source
Cellular and nerve regeneration within a biosynthetic extracellular matrix for corneal transplantation [PDF]
Fengfu Li+9 more
openalex +2 more sources
Topical Soluble Tumor Necrosis Factor Receptor Type I Suppresses Ocular Chemokine Gene Expression and Rejection of Allogeneic Corneal Transplants [PDF]
Ying Qian
openalex +1 more source
Limbal Stem Cells and Corneal Epithelial Regeneration: Current Status and Prospectives [PDF]
The clear cornea functions like a window that controls the entry of light for visual information and plays a protective role. The failure of appropriate repair following corneal injury results in loss of corneal function.
He, J+4 more
core
Neuroimmune pathophysiology of long COVID
Although COVID‐19 was originally considered a respiratory illness, it is now well established that SARS‐CoV‐2 infection can have far‐reaching impacts on the nervous system. Neurological symptoms such as chemosensory dysfunction are frequently observed during acute infection and approximately 10% of COVID‐19 cases will go on to develop new or persistent
Janna K. Moen+2 more
wiley +1 more source
Single and multilayer amniotic membrane transplantation for persistent corneal epithelial defect with and without stromal thinning and perforation [PDF]
Pinnita Prabhasawat
openalex +1 more source
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi+4 more
wiley +1 more source
Role of CD4+ and CD8+ T Cells in Allorecognition: Lessons from Corneal Transplantation [PDF]
Florence Boisgérault+5 more
openalex +1 more source