Results 151 to 160 of about 44,167 (310)

Retrospective study on Encephalitozoon cuniculi infections in 118 cat and 9 dog eyes

open access: yesVeterinary Ophthalmology, EarlyView.
Abstract Purpose This study aims to inform about the clinical image, diagnostic possibilities, and treatment options for cats and dogs diagnosed with ocular encephalitozoonosis. Materials and Methods Medical records of 7 dogs and 75 cats with ocular encephalitozoonosis presented at the Clinical Unit of Ophthalmology of the University of Veterinary ...
Sophie Hofmann‐Wellenhof, Barbara Nell
wiley   +1 more source

Efficiency in Lung Transplant Allocation Strategies [PDF]

open access: yesarXiv, 2018
Currently in the United States, lung transplantations are allocated to candidates according to the candidates' Lung Allocation Score (LAS). The LAS is an ad-hoc ranking system for patients' priorities of transplantation. The goal of this study is to develop a framework for improving patients' life expectancy over the LAS based on a comprehensive ...
arxiv  

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

open access: yesFEBS Open Bio, Volume 15, Issue 5, Page 822-835, May 2025.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma   +3 more
wiley   +1 more source

Enhancing Form Stability: Shrink‐Resistant Hydrogels Made of Interpenetrating Networks of Recombinant Spider Silk and Collagen‐I

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 12, May 6, 2025.
A shrinkage‐resistant hydrogel is developed to confer post‐fabrication shape fidelity. The hydrogel, based on recombinant spider silk protein eADF4(C16)‐RGD and collagen‐I, exhibits tunable mechanical properties and shrink‐resistance in the presence of fibroblasts as well as muscle cells.
Xuen J. Ng   +10 more
wiley   +1 more source

Evaluation of central corneal thickness in keratoconus and normal corneas during air puff indentation [PDF]

open access: yesarXiv, 2019
Purpose: This study aimed to investigate the actual changes of central corneal thickness (CCT) in keratoconus and normal corneas during air puff indentation, by using corneal visualization Scheimpflug technology (Corvis ST). Methods: A total of 32 keratoconic eyes and 46 normal eyes were included in this study.
arxiv  

Japan's Conditional/Time‐Limited Early Approval System in Regenerative Medicine: A Case Study of Rise and Falls of Autologous Skeletal Myoblast Sheets

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1171-1174, May 2025.
Japan's conditional/time‐limited early approval program, initiated in 2014, aimed to advance regenerative medicine by expediting market access. However, the withdrawal of autologous skeletal myoblast sheets (Heartsheet) due to ineffectiveness raises concerns about the balance between rapid approval and scientific integrity.
Hayase Hakariya   +3 more
wiley   +1 more source

Properties of the amniotic membrane for potential use in tissue engineering [PDF]

open access: yes, 2008
An important component of tissue engineering (TE) is the supporting matrix upon which cells and tissues grow, also known as the scaffold. Scaffolds must easily integrate with host tissue and provide an excellent environment for cell growth and ...
Ahmadiani, A   +5 more
core   +1 more source

cGAS/STING signalling in macrophages aggravates obliterative bronchiolitis via an IFN‐α‐dependent mechanism after orthotopic tracheal transplantation in mice

open access: yesClinical and Translational Medicine, Volume 15, Issue 5, May 2025.
• cGAS/STING signalling pathway was activated in macrophages infiltrating allografts. • cGAS/STING signalling pathway in macrophages exacerbated allograft rejection, promoted antigen‐presenting ability of macrophages and enhanced alloreactive T‐cell responses in an IFN‐α2‐dependent manner.
Junhao Wan   +7 more
wiley   +1 more source

Alopecia Areata: Pathogenesis, Diagnosis, and Therapies

open access: yesMedComm, Volume 6, Issue 5, May 2025.
This review probed into the immune factors in the pathogenesis of AA, focusing on the small molecule drugs and biologics for the treatment of AA, and anticipated the research direction in terms of the pathogenesis and targeted therapy of AA. It aims to emphasize the necessity for further exploration of its immunological pathogenesis and therapeutic ...
Tianyou Ma   +7 more
wiley   +1 more source

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