Results 21 to 30 of about 1,194,426 (349)

Different Innate Immune Responses in BALB/c and C57BL/6 Strains following Corneal Transplantation

Journal of Innate Immunity, 2020
Purpose: To investigate immunological differences and the role of CD38+/F4/80 + M1 macrophages in C57BL/6J- and BALB/c-recipient mouse corneal transplantation models. Methods: Allogeneic transplantation was performed crosswise in BALB/c mice and C57BL/6J
T. Bleul, Xinyu Zhuang, A. Hildebrand, C. Lange, D. Böhringer, G. Schlunck, T. Reinhard, T. Lapp   +7 more
semanticscholar   +1 more source

Limbal stem cell transplantation: clinical results, limits, and perspectives [PDF]

, 2018
Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and in an invasion of the cornea by the conjunctival epithelium.
Bruscolini, Alice, Lambiase, Alessandro, Rama, Paolo, Sacchetti, Marta   +3 more
core   +1 more source

A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency [PDF]

, 2019
Producción CientíficaOcular stem cell transplantation derived from either autologous or allogeneic donor corneoscleral junction is a functional cell therapy to manage extensive and/or severe limbal stem cell deficiencies that lead to corneal epithelial ...
Alberca Zaballos, Mercedes, Calonge Cano, Margarita, Fernández Martínez, Itziar, Galindo de la Rosa, Sara, García-Sancho Martín, Francisco Javier, Herreras Cantalapiedra, José María, López Paniagua, Marina, Nieto Miguel, Teresa, Pérez Soto, María Inmaculada, Sánchez García, Ana María de los Ángeles   +9 more
core   +2 more sources

Therapeutic Effect of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage [PDF]

, 2017
Producción CientíficaLimbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss, chronic pain,
Calonge Cano, Margarita, Galindo de la Rosa, Sara, Herreras Cantalapiedra, José María, López Paniagua, Marina, Mata Sampedro, Ana de la, Nieto Miguel, Teresa, Plata Cordero, María, Rey, Esther   +7 more
core   +2 more sources

A brief history of corneal transplantation: From ancient to modern

Oman Journal of Ophthalmology, 2013
This review highlights many of the fundamental concepts and events in the development of corneal transplantation - from ancient times to modern. Tales of eye, limb, and even heart transplantation appear in ancient and medieval texts; however, in the ...
Alexandra X Crawford, Dipika V Patel, Charles NJ McGhee   +2 more
doaj   +1 more source

Long-term observation after transplantation of cultured human corneal endothelial cells for corneal endothelial dysfunction

Stem Cell Research & Therapy, 2022
Background Corneal transplantation is the only way to treat serious corneal diseases caused by corneal endothelial dysfunction. However, the shortage of donor corneal tissues and human corneal endothelial cells (HCECs) remains a worldwide challenge.
Peng Sun, Lin Shen, Yuan-Bin Li, Li-Qun Du, Xin-Yi Wu   +4 more
doaj   +1 more source

High-risk corneal allografts : A therapeutic challenge [PDF]

, 2016
Peer reviewedPublisher ...
Forrester, John V, Griffith, May, Kuffová, Lucia, Rajendran, Vijayalakshmi, Yu, Tian   +4 more
core   +1 more source

Neurotrophic factors and corneal nerve regeneration [PDF]

, 2017
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Lambiase, Alessandro, Sacchetti, Marta
core   +2 more sources

Sterile keratitis following collagen crosslinking

Journal of Ophthalmic & Vision Research, 2014
Purpose: To report a keratoconic eye that developed severe sterile keratitis and corneal scar after collagen crosslinking necessitating corneal transplantation.
Mohammad-Ali Javadi, Sepehr Feizi
doaj   +1 more source

Eccentric lamellar keratolimbal grafts harvested with a manually guided microkeratome [PDF]

, 2007
Background: To perform lamellar keratolimbal allograft transplantation in a one- step procedure with a single graft, we investigated the feasibility of harvesting eccentric lamellar keratolimbal grafts from conventionally processed corneoscleral buttons ...
A. Kampik, Behrens A, Carlo Lackerbauer, Chen JJY, Chen JJY, Chuck RS, Cotsarelis G, Davanger M, Dua HS, Dua HS, Espana EM, Friend J, Grueterich M, Holland EJ, Holland EJ, Huang AJW, Kenneth R. Kenyon, Kenyon KR, Lavker RM, Martin Grueterich, Puangsricharern V, Reinhard T, Schermer A, Shimmura S, Siegfried Priglinger, Sundmacher R, Sundmacher R, Sundmacher R, Tsai RJF, Tseng SCG, Tsubota K, Tungsiripat T, Ulrich Welge-Luessen, Zieske JD   +33 more
core   +1 more source