Results 31 to 40 of about 43,404 (249)

The use of stem cells and keratoprosthesis – special surgery types for corneal disorders (a narrative review)

Journal of Medical Science
Corneal disease and damage can arise from various causes, including infections, corneal dystrophies, trauma and improper contact lens use. These factors can lead to corneal blindness which greatly decreases the patient’s quality of life.
Martyna Dydyk, Ewa Sikorska, Piotr Sikorski, Robert Tomaszewski, Dorota Kopacz   +4 more
doaj   +1 more source

Review: corneal endothelial cell derivation methods from ES/iPS cells

Inflammation and Regeneration, 2019
Globally, approximately 12.7 million people are awaiting a transplantation, while only 185,000 cases of corneal transplantation are performed in a year. Corneal endothelial dysfunction (bullous keratopathy) due to Fuchs’ corneal endothelial dystrophy, or
Shin Hatou, Shigeto Shimmura
doaj   +1 more source

Long-Term Observation and Sequencing Analysis of SKPs-Derived Corneal Endothelial Cell-Like Cells for Treating Corneal Endothelial Dysfunction

Cell Transplantation, 2021
Corneal endothelial dysfunction is a principal cause of visual deficiency. Corneal transplantation is the most effective treatment for corneal endothelial dysfunction.
Lin Shen, Peng Sun, Liqun Du, Jing Zhu, Chengqun Ju, Hui Guo, Xinyi Wu   +6 more
doaj   +1 more source

Case Report: Simultaneous penetrating keratoplasty with autologous simple limbal epithelial transplantation as an alternative to keratoprosthesis [version 3; peer review: 2 approved]

F1000Research, 2023
Introduction and importance: This case report highlights the multidisciplinary approach required to achieve successful anatomical and functional outcomes, in an eye with total limbal stem cell deficiency (LSCD) associated with underlying corneal scarring
Swati Singh, Swapna S. Shanbhag, Supriya Sharma   +2 more
doaj   +1 more source

Tissue engineering a fetal membrane [PDF]

, 2011
The aim of this study was to construct an artificial fetal membrane (FM) by combination of human amniotic epithelial stem cells (hAESCs) and a mechanically enhanced collagen scaffold containing encapsulated human amniotic stromal fibroblasts (hASFs ...
Adam M. Squires, Anna L. David, Bipasha Chowdhury, Che John Connon, Connon C.J., Grinnell F., Ian William Hamley, Jones R.R., Kirkham S.M., Roanne Razalia Jones, Shengli Mi, Trinkaus R.V.   +11 more
core   +1 more source

Case Report: Simultaneous penetrating keratoplasty with autologous simple limbal epithelial transplantation as an alternative to keratoprosthesis [version 2; peer review: 2 approved]

F1000Research, 2023
Introduction and importance: This case report highlights the multidisciplinary approach required to achieve successful anatomical and functional outcomes, in an eye with total limbal stem cell deficiency (LSCD) associated with underlying corneal scarring
Swati Singh, Swapna S. Shanbhag, Supriya Sharma   +2 more
doaj   +1 more source

Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion. [PDF]

, 2020
The advent of cell culture-based methods for the establishment and expansion of human corneal endothelial cells (CEnC) has provided a source of transplantable corneal endothelium, with a significant potential to challenge the one donor-one recipient ...
Aldave, Anthony J, Azimov, Rustam, Boere, Payton M, Chung, Doug D, Frausto, Ricardo F, George, Benjamin L, Hanser, E Maryam, Kao, Liyo, Kurtz, Ira, Mehta, Jodhbir S, Morselli, Marco, Peh, Gary SL, Pellegrini, Matteo, Swamy, Vinay S, Wu, Jessica   +14 more
core  

The impact of corneal allograft rejection on the long-term outcome of corneal transplantation [PDF]

, 2005
© 2005. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/To examine the influence of corneal allograft rejection on the survival of penetrating corneal transplantation, to review
Coster, Douglas John, Williams, Keryn Anne   +1 more
core   +1 more source

Neuropeptide alpha-Melanocyte stimulating hormone preserves corneal endothelial morphology in a murine model of Fuchs dystrophy

Scientific Reports
Fuchs endothelial corneal dystrophy is a heterogenous disease with multifactorial etiology, and genetic, epigenetic, and exogenous factors contributing to its pathogenesis.
Francesca Kahale, Hamid Alemi, Amirreza Naderi, Neha Deshpande, Seokjoo Lee, Shudan Wang, Rohan Bir Singh, Thomas Dohlman, Jia Yin, Ula Jurkunas, Reza Dana   +10 more
doaj   +1 more source

Macrophage depletion impairs corneal wound healing after autologous transplantation in mice. [PDF]

PLoS ONE, 2013
PURPOSE: Macrophages have been shown to play a critical role in the wound healing process. In the present study, the role of macrophages in wound healing after autologous corneal transplantation was investigated by depleting local infiltrated macrophages.
Suxia Li, Bin Li, Haoran Jiang, Yao Wang, Mingli Qu, Haoyun Duan, Qingjun Zhou, Weiyun Shi   +7 more
doaj   +1 more source