Results 21 to 30 of about 23,544 (208)

Efficacy of different amniotic membrane transplantation techniques in patients with inflammatory and degenerative pathology of the cornea

Journal of Ophthalmology, 2016
Introduction. Due to its unique properties, amniotic membrane transplantation took its place in reconstructive surgery of ocular surface. The standard technique for amniotic membrane transplantation does not exist. Purpose.
E. V. Sereda, G. I. Drozhzhina, T. B. Gaidamaka, E.V. Ivanovskaia, V.L. Ostashevskii, O.N. Ivanova, B.M. Kogan   +6 more
doaj   +1 more source

Repeated penetrating corneal transplantation in patients with a previous tectonic transplant

Revista Brasileira de Oftalmologia, 2015
Objective: To analyze, in a university hospital of reference, the rate of a new penetrating corneal transplantation in patients that had previously undergone a tectonic keratoplasty and analyze the results after one year of surgery.
Paulo Rodolfo Tagliari Barbisan, Rosane Silvestre de Castro   +1 more
doaj   +1 more source

The use of stem cells and keratoprosthesis – special surgery types for corneal disorders (a narrative review)

Journal of Medical Science
Corneal disease and damage can arise from various causes, including infections, corneal dystrophies, trauma and improper contact lens use. These factors can lead to corneal blindness which greatly decreases the patient’s quality of life.
Martyna Dydyk, Ewa Sikorska, Piotr Sikorski, Robert Tomaszewski, Dorota Kopacz   +4 more
doaj   +1 more source

Review: corneal endothelial cell derivation methods from ES/iPS cells

Inflammation and Regeneration, 2019
Globally, approximately 12.7 million people are awaiting a transplantation, while only 185,000 cases of corneal transplantation are performed in a year. Corneal endothelial dysfunction (bullous keratopathy) due to Fuchs’ corneal endothelial dystrophy, or
Shin Hatou, Shigeto Shimmura
doaj   +1 more source

Long-Term Observation and Sequencing Analysis of SKPs-Derived Corneal Endothelial Cell-Like Cells for Treating Corneal Endothelial Dysfunction

Cell Transplantation, 2021
Corneal endothelial dysfunction is a principal cause of visual deficiency. Corneal transplantation is the most effective treatment for corneal endothelial dysfunction.
Lin Shen, Peng Sun, Liqun Du, Jing Zhu, Chengqun Ju, Hui Guo, Xinyi Wu   +6 more
doaj   +1 more source

Case Report: Simultaneous penetrating keratoplasty with autologous simple limbal epithelial transplantation as an alternative to keratoprosthesis [version 2; peer review: 2 approved]

F1000Research, 2023
Introduction and importance: This case report highlights the multidisciplinary approach required to achieve successful anatomical and functional outcomes, in an eye with total limbal stem cell deficiency (LSCD) associated with underlying corneal scarring
Swati Singh, Swapna S. Shanbhag, Supriya Sharma   +2 more
doaj   +1 more source

Case Report: Simultaneous penetrating keratoplasty with autologous simple limbal epithelial transplantation as an alternative to keratoprosthesis [version 3; peer review: 2 approved]

F1000Research, 2023
Introduction and importance: This case report highlights the multidisciplinary approach required to achieve successful anatomical and functional outcomes, in an eye with total limbal stem cell deficiency (LSCD) associated with underlying corneal scarring
Swati Singh, Swapna S. Shanbhag, Supriya Sharma   +2 more
doaj   +1 more source

Neuropeptide alpha-Melanocyte stimulating hormone preserves corneal endothelial morphology in a murine model of Fuchs dystrophy

Scientific Reports
Fuchs endothelial corneal dystrophy is a heterogenous disease with multifactorial etiology, and genetic, epigenetic, and exogenous factors contributing to its pathogenesis.
Francesca Kahale, Hamid Alemi, Amirreza Naderi, Neha Deshpande, Seokjoo Lee, Shudan Wang, Rohan Bir Singh, Thomas Dohlman, Jia Yin, Ula Jurkunas, Reza Dana   +10 more
doaj   +1 more source

Macrophage depletion impairs corneal wound healing after autologous transplantation in mice. [PDF]

PLoS ONE, 2013
PURPOSE: Macrophages have been shown to play a critical role in the wound healing process. In the present study, the role of macrophages in wound healing after autologous corneal transplantation was investigated by depleting local infiltrated macrophages.
Suxia Li, Bin Li, Haoran Jiang, Yao Wang, Mingli Qu, Haoyun Duan, Qingjun Zhou, Weiyun Shi   +7 more
doaj   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source