Bilateral Severe Corneal Ulcer in a Patient with Lung Adenocarcinoma Treated with Gefitinib [PDF]
We describe the case of Gefitinib-related bilateral corneal perforation. An 86-year-old female patient had bilateral painless and progressive vision loss due to neurotrophic corneal ulcer, following a 2-month treatment with Gefitinib, a selective ...
Facchinetti F.+4 more
core +3 more sources
Cytotoxic clinical isolates of Pseudomonas aeruginosa identified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones. [PDF]
BackgroundTo determine the relationship between type three secretion genotype and fluoroquinolone resistance for P. aeruginosa strains isolated from microbial keratitis during the Steroids for Corneal Ulcers Trial (SCUT) and for two laboratory strains ...
Acharya, Nisha R+9 more
core +10 more sources
Neurotrophic keratitis in a patient with disseminated lymphangiomatosis. [PDF]
INTRODUCTION: Neurotrophic keratitis, a degenerative corneal disease caused by trigeminal nerve impairment, has many etiologies and remains very difficult to treat.
Charukamnoetkanok, Puwat+2 more
core +2 more sources
Use of ozone-based eye drops. A series of cases in veterinary and human spontaneous ocular pathologies [PDF]
Conjunctivitis, keratoconjunctivitis, and corneal ulcers are common eye disorders frequently diagnosed in both humans and animals, and are currently treated by topical administration of eye drops containing anti-inflammatory and antibacterial agents. The
Marchegiani, Andrea+3 more
core +3 more sources
Neurotrophic factors and corneal nerve regeneration [PDF]
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Lambiase, Alessandro, Sacchetti, Marta
core +2 more sources
Empirical treatment of bacterial keratitis: an international survey of corneal specialists. [PDF]
Background/aimsNew antibiotic agents and changing susceptibility patterns may have changed the empirical treatment of bacterial keratitis. Our objective in this study was to survey cornea specialists' practice patterns in the initial treatment of ...
Austin, Ariana+5 more
core +2 more sources
Actinomycetic corneal ulcer [PDF]
A rare case of keratoactinomycosis developing in the absence of any known ocular trauma is described. It showed a dramatic response to penicillin therapy. Steroids should be cautiously used in the presence of active corneal disease. This case highlights the importance of repeated examination of corneal scrapings.
Mohinder Singh, Baljit Kaur
openaire +2 more sources
Phase 2 randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]
Purpose: To evaluate the safety and efficacy of topical recombinant human nerve growth factor (rhNGF) for treating moderate-to-severe neurotrophic keratitis (NK), a rare degenerative corneal disease resulting from impaired corneal innervation.
Alio, Jorge+45 more
core +1 more source
PURPOSE: The aim of this report is to present the case of a corneal ring ulcer that presented with diagnostic and therapeutic challenges. OBSERVATIONS: A 52-year-old woman was referred by her retina doctors for ulceration of the left cornea and pain 8 days after intravitreal ranibizumab injection for diabetic macular edema.
Khaled Alhajraf+2 more
openaire +3 more sources