Results 41 to 50 of about 18,554 (206)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Kingella kingae Keratitis in a Child with Underlying Vernal Keratoconjunctivitis

Case Reports in Ophthalmological Medicine, 2017
Kingella kingae had rarely been reported as a causative organism for corneal ulcer and had not been described before in vernal keratoconjunctivitis (VKC).
Salim Nurul-Laila, Khai-Siang Chai, Ahmad Tajudin Liza-Sharmini, Ismail Shatriah   +3 more
doaj   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

A study on the most prevalent bacterial cause of corneal ulcer and their susceptibility to five common types of ophthalmic antibiotics [PDF]

Trends in Pharmaceutical Sciences, 2020
Purpose: Proper diagnosis of the corneal ulcer is one the most important efforts in the eyes medical urgencies. The aim of this study was to determine the bacteriological profile and in vitro antibiotic resistance of the bacteria isolated from the eyes of
Nazafarin Hatami-Mazinani, Afsaneh Vazin, Abdollah Bazargani, Mahmood Nejabat   +3 more
doaj   +1 more source

Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs

The Anatomical Record, EarlyView.
Abstract Brachycephaly in domestic rabbits is increasingly perceived by welfare organizations as associated with significant health complications, particularly oral pathologies. Despite this perception, comparative anatomical research into rabbit brachycephaly is limited compared to that of dogs and cats, compelling an in‐depth examination of its ...
Helaina Cressy, Alice Nishigaki, Matthew C. Gage, Renato L. Previdelli   +3 more
wiley   +1 more source

A Segmentation-Based Automated Corneal Ulcer Grading System for Ocular Staining Images Using Deep Learning and Hough Circle Transform

Algorithms
Corneal ulcer is a prevalent ocular condition that requires ophthalmologists to diagnose, assess, and monitor symptoms. During examination, ophthalmologists must identify the corneal ulcer area and evaluate its severity by manually comparing ocular ...
Dulyawat Manawongsakul, Karn Patanukhom
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Studying the Effect of Dexamethasone and Water Extract Apricot on Experimental Chemical Corneal Ulcer in Rabbit

مجلة علوم ذي قار, 2019
The present study was designed to evaluate the effect of apricot and dexamethasone on rabbit eye ulcer. Bilateral corneal ulcers were induced by a filter paper disk (4mm diameter) immersed with NaOH (1N) on central axis of cornea in 20 rabbits.
Abdalbari Abbas Alfaris
doaj  

A case of lattice corneal dystrophy type 1 with bilateral Mooren's ulcer

American Journal of Ophthalmology Case Reports, 2023
Purpose: To report a rare case of lattice corneal dystrophy type 1 (LCD1) with bilateral Mooren's ulcer. Observations: This case involved a 62-year-old male patient with LCD1 who presented with the primary complaint of experiencing pain and photophobia ...
Kanae Kayukawa, Koji Kitazawa, Koichi Wakimasu, Chie Sotozono, Shigeru Kinoshita   +4 more
doaj   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source