Results 51 to 60 of about 20,427 (255)

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

open access: yesAdvanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi   +4 more
wiley   +1 more source

Efficacy of Tectonic Corneal Patch Graft for Progressive Peripheral Corneal Thinning [PDF]

open access: yes, 2014
Objectives: To report the results of tectonic corneal patch graft (TCPG) in patients with progressive peripheral corneal thinning (PCT). Materials and Methods: In this study, we included 8 patients who underwent TCPG for PCT or perforated corneal ...
Onat, Mustafa   +21 more
core   +1 more source

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

open access: yesAdvanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino   +7 more
wiley   +1 more source

A Segmentation-Based Automated Corneal Ulcer Grading System for Ocular Staining Images Using Deep Learning and Hough Circle Transform

open access: yesAlgorithms
Corneal ulcer is a prevalent ocular condition that requires ophthalmologists to diagnose, assess, and monitor symptoms. During examination, ophthalmologists must identify the corneal ulcer area and evaluate its severity by manually comparing ocular ...
Dulyawat Manawongsakul, Karn Patanukhom
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Experimental study on cryotherapy for fungal corneal ulcer [PDF]

open access: yes, 2015
BACKGROUND: Fungal corneal ulcer is one of the major causes of visual impairment worldwide. Treatment of fungal corneal ulcer mainly depends on anti-fungal agents.
Yingxin Chen   +11 more
core   +1 more source

Studying the Effect of Dexamethasone and Water Extract Apricot on Experimental Chemical Corneal Ulcer in Rabbit

open access: yesمجلة علوم ذي قار, 2019
The present study was designed to evaluate the effect of apricot and dexamethasone on rabbit eye ulcer. Bilateral corneal ulcers were induced by a filter paper disk (4mm diameter) immersed with NaOH (1N) on central axis of cornea in 20 rabbits.
Abdalbari Abbas Alfaris
doaj  

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

open access: yesAdvanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao   +8 more
wiley   +1 more source

A case of lattice corneal dystrophy type 1 with bilateral Mooren's ulcer

open access: yesAmerican Journal of Ophthalmology Case Reports, 2023
Purpose: To report a rare case of lattice corneal dystrophy type 1 (LCD1) with bilateral Mooren's ulcer. Observations: This case involved a 62-year-old male patient with LCD1 who presented with the primary complaint of experiencing pain and photophobia ...
Kanae Kayukawa   +4 more
doaj   +1 more source

Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs

open access: yesThe Anatomical Record, EarlyView.
Abstract Brachycephaly in domestic rabbits is increasingly perceived by welfare organizations as associated with significant health complications, particularly oral pathologies. Despite this perception, comparative anatomical research into rabbit brachycephaly is limited compared to that of dogs and cats, compelling an in‐depth examination of its ...
Helaina Cressy   +3 more
wiley   +1 more source

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