Results 71 to 80 of about 24,848 (319)

Supramolecular Assembly of Triterpenoids: Current State and Biomedical Perspectives

Aggregate, EarlyView.
Triterpenoids serve as both exceptional molecular motifs for supramolecular assembly and versatile therapeutic agents, offering broad biological functions to improve health outcomes and enhance treatment efficacy. This review comprehensively summarizes recent advances in triterpenoid‐based supramolecular systems, including their roles as functional ...
Jie Zhong, Juan C. Mareque‐Rivas, Xinmiao Lan, Yu‐Xiong Su   +3 more
wiley   +1 more source

Rapid deterioration of Mooren’s ulcers after conjunctival flap: a review of 2 cases

BMC Ophthalmology, 2017
Background Conjunctival flaps are a widely used treatment for numerous corneal ulcers that are caused by microorganismal infections. However, whether it can be performed on immune-mediated corneal ulcers is controversial. Case presentation We present two
Saiqun Li, Yuqing Deng, Caiyuan Du, Haixiang Huang, Jing Zhong, Ling Chen, Bowen Wang, Jin Yuan   +7 more
doaj   +1 more source

Practical Guidance on Clinical Management of Belantamab Mafodotin‐Associated Ocular Events

American Journal of Hematology, EarlyView.
ABSTRACT Importance Belantamab mafodotin (belamaf)‐containing regimens are effective treatment options for patients with relapsed and/or refractory multiple myeloma. Ocular events are a common adverse effect of belamaf treatment, which can be managed by physicians, following appropriate training, to minimize their impact on the patient.
Evangelos Terpos, Suzanne Trudel, María‐Victoria Mateos, Nicolás Alejandre, Kathryn Colby, Meletios A. Dimopoulos, Simona Degli Esposti, Asim V. Farooq, Maria Gavriatopoulou, Francesca Gay, Vania Hungria, K. Martin Kortüm, Xavier Leleu, Sagar Lonial, Hang Quach, Lugui Qiu, Karthik Ramasamy, Kazuhito Suzuki, Katja C. Weisel, Paul Richardson   +19 more
wiley   +1 more source

Experimental purulent corneal ulcer in rabbits as a model to study ocular dosage forms [PDF]

, 2018
Aim. The aim of this work was to develop experimental model of purulent corneal ulcer in rabbits for its application in the studies of ocular dosage forms. Methods. Rabbits body temperature was measured in three groups: (1) without corneal injury; (2)
Adambosynov, Balgyn, Bayachmetov, Aibol, Khutoryanskiy, Vitaliy V., Mussin, Marat N., Ozhmukhametova, Elvira K.   +4 more
core   +2 more sources

Genotype–Phenotype Correlations, Mortality, and Clinical Insights in Keratitis–Ichthyosis–Deafness Syndrome: A Comprehensive Review and Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero, Marco Antonio Hernández Lepe, José de Jesús Manríquez Torres, Diego Daniel Aguirre‐Gómez, Natsuo Hayashi‐Mercado, Genaro Rodríguez Uribe, Tadeo Cerón, María Ruiz‐Gamboa, Jesús Alonso Gándara‐Mireles, Ismael Lares‐Asseff, Verónica Loera‐Castañeda, Jorge Alvelais‐Palacios, Lucrecia Arzamendi‐Cepeda, Lidia Magdalena Castañeda‐González, Adolfo García‐Barrón, Francisco Yamal Quiroz Herrera, Francisco González‐Salazar, Horacio Almanza‐Reyes   +17 more
wiley   +1 more source

Efficacy of Lamellar Keratoplasty with Acellular Porcine Corneal Stroma in Treatment for Infectious Central and Peripheral Corneal Ulcers

Therapeutics and Clinical Risk Management, 2021
Yingxin Chen, Linlin Zhang, Zhiling Liu, Qiming Liu, Minghong Gao Department of Ophthalmology, General Hospital of Northern Theater Command, Shenyang, People’s Republic of ChinaCorrespondence: Minghong GaoDepartment of Ophthalmology, General ...
Chen Y, Zhang L, Liu Z, Liu Q, Gao M
doaj  

The use of nerve growth factor in herpetic keratitis: a case report

Journal of Medical Case Reports, 2007
Background We evaluate the role of nerve growth factor (NGF) eye drops to treat a herpetic corneal ulcer resistant to systemic and local acyclovir treatment in an HIV-positive patient.
Cellini Mauro, Leonetti Pietro, Campos Emilio C   +2 more
doaj   +1 more source

Acute Herpetic Keratitis: What is the Role for Ganciclovir Ophthalmic Gel? [PDF]

, 2012
Herpes simplex keratitis (HSK) is a major cause of corneal blindness in the world. Following the primary infection, the virus enters into a latent phase.
Hamrah, Pedram, Sahin, Afsun
core   +3 more sources

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

Animal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica, Suzana Stanisavljević, Dragica Mićanović, Ivana Stojanović, Đorđe Miljković   +4 more
wiley   +1 more source

FREQUENCY OF DEVIATIONS FROM NORMAL VALUES IN THE BLOOD SUBPOPULATIONS’ PROFILE IN THE PATIENTS WITH CENTRAL CORNEAL ULCERS

Медицинская иммунология, 2018
This article presents a detailed description of shifts in subsets of blood lymphocyte subpopulations associated with development of the corneal ulcerative lesions as well as during penetrating keratoplasty.We have revealed some general changes typical ...
I. G. Kulikova, N. V. Balatskaya, L. A. Kovaleva, P. V. Makarov   +3 more
doaj   +1 more source