Results 41 to 50 of about 392 (137)

Porokeratosis Masquerading As Lupus Vulgaris

Indian Journal of Dermatology, 2004
Porokeratosis is a specific disorder of kerstinization characterized histologically by cornoid lamella. Lesions of porokeratosis present varied features, often mimicking other dermatological disorders. Herein, we report a case of porokeratosis of Mibelli
Das Sudip, Banerjee Gautam
doaj  

Ultraviolet‐Induced Fluorescence Dermatoscopy in the Management of Non‐Neoplastic Dermatoses—A Narrative Review

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Ultraviolet‐induced fluorescence dermatoscopy (UVFD) is a novel, promising dermatoscopic modality that uses excitation–emission phenomena to visualize endogenous and exogenous fluorophores. By highlighting both visible‐light emission signals and absorption patterns, it provides valuable diagnostic data that complement conventional dermatoscopy ...
Paweł Pietkiewicz, Natalia Salwowska, Anna Słomiak-Wąsik, Yasmeen Jabeen Bhat, Anna Waśkiel-Burnat, Cristian Navarrete-Dechent, Enzo Errichetti, Suraiya Saleem   +7 more
wiley   +1 more source

Topical Cholesterol and Statin Therapy for Porokeratosis: A Systematic Review and Exploratory Meta‐Analysis

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background Porokeratosis comprises a group of clinically diverse keratinization disorders unified by the cornoid lamella and increasingly understood through alterations in the mevalonate/cholesterol biosynthesis pathway, including germline variants, somatic second‐hit events, clonal mosaicism, and emerging epigenetic mechanisms.
Maryam Sajjad, Leena Alotaibi, Ahmed N. Alqefari, Norah Aljabr, Ahad Abdulaziz Alruhaymi, Turki Saeed Alkahtani, Ahmed Ayed N. Alanazi, Naif Abed Alshamari, Aliyah Abdulmohsen Alabdulqader, Alanoud Abdullah Al Daej, Nawal Hussain Hibili, Zain Abbara, Elissa Nassif   +12 more
wiley   +1 more source

Efficacy and Safety of Topical Statin Therapy for Porokeratosis: A Systematic Review and Meta‐Analysis

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background and Objective Porokeratosis comprises a heterogeneous group of keratinization disorders with malignant transformation potential. While multiple therapeutic options exist, clinical outcomes remain suboptimal. Emerging evidence suggests promising efficacy of topical statin therapy, though systematic evaluation is currently lacking.
Xingyu Li, Yue Hu, Jie Liu, Suraiya Saleem   +3 more
wiley   +1 more source

Malignant Transformation in a Genitocrural Porokeratosis : A Case Report

Nepal Journal of Dermatology, Venereology & Leprology
Porokeratosis is a rare heterogenous group of keratinization disorder with an unclear pathogenesis, and has varied clinical presentations. It may present with annular papules or plaques with central atrophy and clinically and histologically distinct ...
Mrunali Joshi, Pooja Agarwal, Raju Chaudhary, Kalgi Baxi   +3 more
doaj   +3 more sources

Porokeratosis: Two Faces, One Family

Case Reports in Dermatology, 2009
Porokeratosis is a disorder of keratinisation whose pathogenesis is yet unclear. It has been postulated that it results from the proliferation of an abnormal clone of keratinocytes, triggered by several factors, such as immunosuppression or prolonged ...
S. Lembo, L. Panariello, L. Nugnes, C. Lembo, F. Alaya   +4 more
doaj   +1 more source

A Patient With Concurrent Hidradenitis Suppurativa and Porokeratosis Palmaris et Plantaris Disseminata: Case Report and Review of Autoinflammatory Keratinization Diseases

Journal of Cutaneous Pathology, Volume 52, Issue 4, Page 272-277, April 2025.
ABSTRACT The term autoinflammatory keratinization diseases (AIKDs) was recently proposed as a unifying concept for diseases characterized by inflammation in the epidermis and upper dermis which leads to hyperkeratosis, caused by genetic perturbations of the innate immune system.
Meredith C. Rogers, Mark Ash, Amanda Hernandez, Gregory A. Hosler   +3 more
wiley   +1 more source

Porokeratoses: an update on pathogenesis and treatment

International Journal of Dermatology, Volume 64, Issue 1, Page 62-71, January 2025.
Abstract Porokeratoses (PK) are a group of uncommon dermatoses characterized by abnormal epidermal differentiation due to a disorder of the mevalonate metabolic pathway. Several clinical subtypes exist that can be associated with the same patient or affect different patients within a family and could, therefore, be different expressions of one disease.
Konstantinos‐Antonios Kostopoulos‐Kanitakis, Jean Kanitakis   +1 more
wiley   +1 more source

A unique porokeratotic variant of inflammatory linear verrucous epidermal nevus

Indian Journal of Paediatric Dermatology, 2017
Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare variant of nevoid linear inflammatory dermatoses which appear most often in the first 6 months of life and persists for many years or even whole life.
Anup Kumar Tiwary, Dharmendra Kumar Mishra   +1 more
doaj   +1 more source

Establishment of a Mouse Model for Porokeratosis Due to Mevalonate Diphosphate Decarboxylase Deficiency

Skin Research and Technology, Volume 30, Issue 9, September 2024.
ABSTRACT Introduction Porokeratosis (PK) is an autoinflammatory keratinization disease (AIKD) characterized by circular or annular skin lesions with a hyperkeratotic rim, pathologically shown as the cornoid lamella. Four genes that cause PK are associated with the mevalonate (MV) pathway.
Kexin Peng, Wenghong Wong, Qiaoan Zhang, Yumeng La, Zhen Tian, Ruilin Sun, Loksi Ho, Kaihang Yang, Jiewen Pan, Jing Luan, Zhenmin Niu, Zhenghua Zhang   +11 more
wiley   +1 more source