Results 51 to 60 of about 448 (165)

Darier disease—A review highlighting new insights from the Darier Disease International Task Force

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz, Alain Hovnanian, Grace Xiong, Dedee Frances Murrell, Simon M. Mueller, Khaled Ezzedine, Nessa Aghazadeh Mohandesi, Ahmed Salem Aldhaheri, Nissim Asayag, Eulalia Baselga, Chen Nadler, Keith Choate, Chia‐Yu Chu, John Robert Edminister, Emmanuella Guenova, Melis Gönülal, Antoni Gostynski, Ankan Gupta, Lalit Kumar Gupta, Juliette Mazereeuw‐Hautier, Wolfram Hoetzenecker, Peter Itin, Marek Jankowski, Akiharu Kubo, Haur Yueh Lee, Julia Scott Lehman, Anfisa Lepekhova, Márta Medvecz, Jemima E. Mellerio, Verena Moosbrugger‐Martinz, Amy S. Paller, Dóra Plázár, Amadeu José Rodrigues Queiróz, Josep Riera‐Monroig, Ralph Rosa, Matthias Schmuth, Maella Severino Freire, Itzhak Shabat, Jonathan Shapiro, Cory L. Simpson, Diego Soto‐García, Alexander J. Stratigos, Gianluca Abel Tadini, Takuya Takeichi, Kaushal K. Verma, Jakob D. Wikström, Alexander Zink, Michael Ziv, Alexander Navarini, Roni Pircha Dodiuk‐Gad   +49 more
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Porokeratosis of mibelli of upper lip extending into oral mucosa

Clinical Dermatology Review, 2017
Porokeratosis is a rare specific disorder of keratinization with distinct clinical and histopathological features with rare malignant degeneration. Clinically, it is characterized by papular lesions or annular plaques with central atrophy and peripheral ...
Ragunatha Shivanna, Meenakshi Kapoor, Gangaiah Narendra   +2 more
doaj   +1 more source

Successful Treatment of Refractory Disseminated Superficial Actinic Porokeratosis With Topical Ruxolitinib

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT This is the first documented case of disseminated superficial actinic porokeratosis (DSAP) successfully treated with topical ruxolitinib. The patient experienced near‐complete clearance after three months, suggesting that topical JAK inhibition may be an effective and well‐tolerated option for refractory porokeratosis.
Joe Khodeir, Paul Ohanian, Marielena Ohanian   +2 more
wiley   +1 more source

Genitogluteal porokeratosis in an HIV-positive man: a case report and review of the literature on genital porokeratosis [PDF]

, 2018
Genitogluteal porokeratosis is a disorder of keratinization that may present in men in their fourth decade of life. We describe a 52-year-old human immunodeficiency virus (HIV)-positive man with history of anal squamous cell carcinoma who developed ...
Vazirnia, Aria, Bari, Omar, Romero, Laura S, Cohen, Philip R   +3 more
core   +1 more source

Mutation analysis of the MVD gene in a chinese family with disseminated superficial actinic porokeratosis and a chinese literature review

Indian Journal of Dermatology, 2021
Background: Porokeratosis (PK) is a rare, heterogeneous group of keratinization disorders with an autosomal dominant inheritance pattern and is characterized by the presence of cornoid lamella.
Wenjun Qian, Jing Wu, Huayang Tang, Qi Zhen, Huiyao Ge, Jinping Gao, Jingjing Chen, Yuling Chang, Wenjun Wang, Liangdan Sun   +9 more
doaj   +1 more source

Efficacy and Safety of Topical Statin Therapy for Porokeratosis: A Systematic Review and Meta‐Analysis

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background and Objective Porokeratosis comprises a heterogeneous group of keratinization disorders with malignant transformation potential. While multiple therapeutic options exist, clinical outcomes remain suboptimal. Emerging evidence suggests promising efficacy of topical statin therapy, though systematic evaluation is currently lacking.
Xingyu Li, Yue Hu, Jie Liu, Suraiya Saleem   +3 more
wiley   +1 more source

A Patient With Concurrent Hidradenitis Suppurativa and Porokeratosis Palmaris et Plantaris Disseminata: Case Report and Review of Autoinflammatory Keratinization Diseases

Journal of Cutaneous Pathology, Volume 52, Issue 4, Page 272-277, April 2025.
ABSTRACT The term autoinflammatory keratinization diseases (AIKDs) was recently proposed as a unifying concept for diseases characterized by inflammation in the epidermis and upper dermis which leads to hyperkeratosis, caused by genetic perturbations of the innate immune system.
Meredith C. Rogers, Mark Ash, Amanda Hernandez, Gregory A. Hosler   +3 more
wiley   +1 more source

Disseminated porokeratosis in an infant with craniosynostosis

, 1990
An infant with craniosynostosis and other congenital defects developed a progressive skin rash from the age of 1 month. Histological examination revealed dyskeratosis and a cornoid lamella suggestive of porokeratosis.
Harper, J. I., David, T. J., Michaels, M., Judge, M. R., Sams, V. R.   +4 more
core   +1 more source

Bullous and pruritic variant of disseminated superficial actinic porokeratosis: successful treatment with grenz rays

, 1999
We describe a case of intensively pruritic and partially bullous disseminated superficial actinic prorokeratosis, with acute flare-ups. Histopathological examination showed the characteristic cornoid lamella and subepidermal blister formation in one ...
Ricci, C., Rosset, A., Panizzon, R. G.   +2 more
core   +1 more source