Results 221 to 230 of about 1,004,947 (332)

cDC1 Subtype‐Specific In Vivo Targeting of Liposomes

Advanced Science, EarlyView.
Dendritic cells, particularly the cDC1 subtype, offer a promising target for drug delivery via liposomes due to their pivotal role in immune regulation, allowing for amplified therapeutic responses. Herein, we show an integration of physicochemical characterization and cell experiments to achieve effective in vivo cDC1 targeting through anti‐CLEC9A ...
Maximilian Schaaf, Michael Fichter, Lin Jian, Felicia Schön, Carina Jung, Paul Schneider, Kai Speth, Ana Mateos‐Maroto, Volker Mailänder, Kaloian Koynov, Svenja Morsbach, Katharina Landfester   +11 more
wiley   +1 more source

Coronal Streamer Brightness Profiles Investigated with BriLo Using Parker Solar Probe White-Light Data. [PDF]

Sol Phys
Cappello GM, Temmer M, Lienhart A, Nisticò G, Stenborg G, Linton MG, De Leo Y, Heinemann SG, Liewer PC, Howard RA, Bothmer V.   +10 more
europepmc   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Linking kinetochore attachment to checkpoint control: the role of Aurora B in BubR1 acetylation. [PDF]

Nucleic Acids Res
Choi SY, Park H, Kim SS, Kim H, Park S, Lee H.   +5 more
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

Gold nanoparticle transport across tumour-associated biological barriers: <i>in vitro</i> models, imaging, and quantification.

Nanoscale
Christodoulou C, MacRobert AJ, Loizidou M, Ramesh B, Ricketts K, Thrasivoulou C, Jell G, Patra HK.   +7 more
europepmc   +1 more source

Correction: Integrated multidisciplinary analysis of mobile digital radiographic acquisitions of the mummies of the Hermits from the Sanctuary of Madonna della Corona (Italy - 17th to 19th Century CE). [PDF]

Front Med (Lausanne)
Larentis O, Gorini I, Campus M, Lorenzetti M, Mansueto G, Bortolotto S, Zappa E, Gregorini A, Rampazzi L, Vanin S, Carta G, Carli A, Simonaitis L, De Luca L, Tonina E.   +14 more
europepmc   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

Impact of Proteins on the Cellular Uptake of Carbon Nanodots. [PDF]

ACS Omega
Liu Z, Yan H, Gómez IJ, Carrillo Carion C, Arnaiz B, Zhu D, Prato M, Parak WJ, Feliu N, Cacioppo M.   +9 more
europepmc   +1 more source