Results 191 to 200 of about 1,639,958 (288)

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo   +10 more
wiley   +1 more source

Distal Coronary Artery Thrombus After Primary PCI Resolved by Excimer Laser Coronary Angioplasty. [PDF]

open access: yesJACC Case Rep
Mori T   +9 more
europepmc   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa   +3 more
wiley   +1 more source

Chronic Obstructive Pulmonary Disease as an Independent Predictor of Left Main Coronary Artery Disease. [PDF]

open access: yesMed Sci (Basel)
Ragnoli B   +5 more
europepmc   +1 more source

Coronary Angioplasticity

open access: yesJACC: Cardiovascular Interventions, 2016
Bill D, Gogas, Habib, Samady
openaire   +2 more sources

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of TCE‐secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

open access: yesAdvanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang   +27 more
wiley   +1 more source

Dilute but Dense – Reversible Crosslinking Enables Water‐Rich (Bio)polymer Condensates

open access: yesAdvanced Science, EarlyView.
Reversible crosslinking between two types of (bio)polymers drives liquid–liquid phase separation even in good solvent. The arrangement of binding motifs controls condensate formation and density, and internal network structure. Simulations and theory reveal a closed‐loop coexistence phase diagram at very low monomer concentrations and re‐entrant ...
Xinxiang Chen   +4 more
wiley   +1 more source

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