Results 91 to 100 of about 66,092 (249)

Evaluation of the Safety, Efficacy and Pharmacokinetics of BGM0504 in Chinese Adults With Type 2 Diabetes: A Multicentre, Randomised, Controlled and Double‐Blind Phase II Trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim This study aimed to evaluate its safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy in Chinese adults with T2DM and to preliminarily compare its efficacy and safety with semaglutide through multiple subcutaneous injections. Materials and Methods In this multicentre, randomised, placebo‐controlled and semaglutide‐positive‐
Ping Jin   +9 more
wiley   +1 more source

Response to the Letter: “Coronary Artery Ectasia and Aneurysm” [PDF]

open access: yes
Coronary artery aneurysms (CAA) and ectasia (CAE) are significant yet underdiagnosed conditions that influence coronary artery disease (CAD) outcomes. Although CAA and CAE were not included or considered in our study, they undoubtedly have the potential ...
Alexey Goncharov   +2 more
core   +1 more source

A giant left main coronary artery aneurysm [PDF]

open access: yes, 2015
WOS: 000421966900020PubMed ID: 26142803A 67-year old woman with a history of hypertension and atrial fibrillation presented with exertional dyspnea. Her electrocardiogram was consistent with diffuse ST segment depression on the pericardial leads.
Karaca, Oguz   +4 more
core   +1 more source

Prediabetes, Malignant Ventricular Hypertrophy and Stroke: The SPRINT Trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Prediabetes and left ventricular hypertrophy (LVH) are common risk factors in adults with hypertension. Whether their coexistence, particularly in the presence of subclinical myocardial injury or stress (malignant LVH), confers a heightened stroke risk is unknown.
Arnaud D. Kaze   +7 more
wiley   +1 more source

Effect of propranolol on regional myocardial function in anesthetized open-chest dogs with myocardial ischemia

open access: yes, 1978
Effects of propranolol on ischemic segmental function were studied in anesthetized open-chest dogs. Two segment-length gauges were used for measuring the regional myocardial function: one was sutured on to the left ventricular surface perfused by the ...
Yoshida, Hidenori   +7 more
core   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

open access: yesThe FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Surgical treatment of giant coronary artery aneurysm

open access: yes, 2005
ObjectiveGiant coronary artery aneurysm is an extremely uncommon disease. Most previous reports have involved only single cases. This report describes 6 patients with giant coronary artery aneurysm, examines its causes, and aims to establish the optimal ...
Qingyu Wu   +23 more
core   +1 more source

Management of Coronary Artery Aneurysms

open access: yesJACC: Cardiovascular Interventions, 2018
Aneurysmal dilation of coronary arteries is observed in up to 5% of patients undergoing coronary angiography. Due to their poorly elucidated underlying mechanisms, their variable presentations, and the lack of largescale outcome data on their various treatment modalities, coronary artery aneurysms and coronary ectasia pose a challenge to the managing ...
Akram, Kawsara   +5 more
openaire   +2 more sources

Systematic screening for age‐related comorbidities: Health care optimization among persons with HIV in an outpatient setting

open access: yesHIV Medicine, EarlyView.
Abstract Background Age‐related comorbidities occur earlier and more frequently in people with HIV (PWH) than in the general population and have emerged as a key challenge in long‐term HIV care. Unfortunately, many of these conditions remain undiagnosed, and systematic screening in clinical practice remains limited.
Anna Katrine Haslund Roed   +4 more
wiley   +1 more source

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