Results 101 to 110 of about 1,697 (168)

Evaluation of the Safety, Efficacy and Pharmacokinetics of BGM0504 in Chinese Adults With Type 2 Diabetes: A Multicentre, Randomised, Controlled and Double‐Blind Phase II Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7073-7082, August 2026.
ABSTRACT Aim This study aimed to evaluate its safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy in Chinese adults with T2DM and to preliminarily compare its efficacy and safety with semaglutide through multiple subcutaneous injections. Materials and Methods In this multicentre, randomised, placebo‐controlled and semaglutide‐positive‐
Ping Jin, Linong Ji, Yangqing Huang, Haifeng Ding, Daosheng Xie, Xiaohui Jiang, Xuemei Yuan, Zhao Cao, Haibin Zhang, Jiandong Yuan   +9 more
wiley   +1 more source

Triple-vessel coronary involvement and giant aneurysm in a 6-year-old boy with kawasaki disease: a case report

BMC Cardiovascular Disorders
Background Kawasaki disease (KD) is an acute systemic vasculitis of unknown origin. It represents one of the most important causes of acquired heart disease in the pediatric population. Coronary artery involvement is the most serious complication and may
Mohammad-Taghi Majnoon, Mohammad Mehdi Rajabi, Sahar Hemati, Vahid Ziaee, Mohammad Rafati Navaei, Behdad Gharib   +5 more
doaj   +1 more source

Prediabetes, Malignant Ventricular Hypertrophy and Stroke: The SPRINT Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6725-6734, August 2026.
ABSTRACT Aims Prediabetes and left ventricular hypertrophy (LVH) are common risk factors in adults with hypertension. Whether their coexistence, particularly in the presence of subclinical myocardial injury or stress (malignant LVH), confers a heightened stroke risk is unknown.
Arnaud D. Kaze, Stephen P. Juraschek, Jordana B. Cohen, Siddharth Singh, Chiadi E. Ndumele, Christie M. Ballantyne, Jarrett D. Berry, Justin B. Echouffo‐Tcheugui   +7 more
wiley   +1 more source

Left Atrial Coupling Indexes as New Mortality Predictors in Chronic Chagas Disease

Echocardiography, Volume 43, Issue 8, August 2026.
Echocardiographic left atrial coupling indexes are promising prognostic markers of dismal outcome in Chagas disease. They were associated with all‐cause mortality independent from age, sex, and echocardiographic indexes, including LV ejection fraction, supporting their potential clinical relevance.
Roberto M. Saraiva, Mauro Felippe F. Mediano, Henrique H. Veloso, Marcelo T. Holanda, Andréa R. Costa   +4 more
wiley   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, Volume 293, Issue 16, Page 4789-4804, August 2026.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

A Case Report of Myocardial Infarction Complicated With Blood Pressure Fluctuations Caused by Pheochromocytoma

The Journal of Clinical Hypertension, Volume 28, Issue 8, August 2026.
ABSTRACT Pheochromocytoma typically presents with sustained or paroxysmal hypertension, but initial manifestation as acute non‐ST‐segment elevation myocardial infarction (NSTEMI) is rare. Peri‐procedural hemodynamic fluctuations are often dramatic, making diagnosis and management challenging.
HuiPing Li, Wei Yang, Yu Feng, You Zhang, Ganxin Yan, ChuanYu Gao   +5 more
wiley   +1 more source

β3‐AR/β‐arrestin2 Interaction Triggers Cardiac Fibrosis Through JNK/c‐Jun Pathway in Cardiac Fibroblasts

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Myocardial fibrosis (MF) is a critical pathological substrate of heart failure (HF), and β3‐adrenergic receptor (β3‐AR) has been implicated in cardiac remodelling with controversial roles. This study aimed to clarify the pro‐fibrotic mechanism of β3‐AR in cardiac fibroblasts and its association with β‐arrestin2‐mediated biased activation ...
Zhongcheng Xu, Min Zhu, Chun Zhou, Juncang Duan, Jian Ding, Jun Liu, Xuan Ying, Jie Wu, Yang Dong, Wenbiao Wang, Zhaohui Qiu   +10 more
wiley   +1 more source

The Effect of 6 Months of Dietary Counselling on Sleep Outcomes Among Patients With Cardiovascular Diseases: A Randomised Controlled Trial

Journal of Sleep Research, Volume 35, Issue 4, August 2026.
ABSTRACT Sleep problems are highly prevalent among patients with cardiovascular diseases (CVD). We examined the effect of dietary counselling on sleep outcomes among patients with CVD. We performed secondary analyses within a previously conducted six‐month randomised controlled trial among patients with CVD.
Auke J. C. F. Verkaar, Iris van Damme, Eva R. van Veldhuisen, H. Myrthe Boss, Johanna M. Geleijnse, Renate M. Winkels   +5 more
wiley   +1 more source

Aneurysm of Coronary Arteries in an Infant [PDF]

Postgraduate Medical Journal, 1962
S D, WELLER, S M, NEWSTEAD
openaire   +2 more sources

Left Main Coronary Artery Aneurysm

Journal of Tehran University Heart Center, 2016
Aneurysms of the left main coronary artery are exceedingly rare clinical entities, encountered incidentally in approximately 0.1% of patients who undergo routine angiography.
Hossein Doustkami, Nasrollah Maleki, Zahra Tavosi   +2 more
doaj