Results 61 to 70 of about 691,642 (250)

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert, Gudny Anna Arnadottir, Laura Bedinger, Nicola Brunetti‐Pierri, Jennifer Cech, Xin Chen, Yanmin Chen, Erika Chick, Sarah Dyack, Madeleine Franchi, Tanja Frey, David Genevieve, Ian Glass, Jorge Granadillo, Kelly A. Keener, Sara B. MacKay, Paige McDunnah, Vinod K. Misra, Kristin G. Monaghan, Sureni V. Mullegama, Cristina Peduto, Leia Peterman‐Prather, Anita Rauch, Cherith Somerville, Kari Stefansson, Katharina Steindl, Patrick Sulem, Telma Sulem, Pamela Trapane, Roberta Zeuli, Samuel Zinner, Kosuke Izumi   +31 more
wiley   +1 more source

Ablation at the Coronary Sinus Diverticular Neck for a Posteroseptal Accessory Pathway With Coronary Sinus Ostial Atresia. [PDF]

J Arrhythm
After failed annular ablation for a posteroseptal accessory pathway with coronary sinus ostial atresia, direct coronary sinus angiography delineated a coronary sinus diverticulum with left atrial drainage. Targeted mapping localized the effective ablation site to the diverticular neck, where radiofrequency delivery eliminated accessory pathway ...
Kitahara T, Shimojo M, Yanagisawa S, Suzuki T, Inden Y.   +4 more
europepmc   +2 more sources

Invasive coronary physiology in patients with angina and non-obstructive coronary artery disease: a consensus document from the coronary microvascular dysfunction workstream of the British Heart Foundation/National Institute for Health Research Partnership [PDF]

, 2022
Nearly half of all patients with angina have non-obstructive coronary artery disease (ANOCA); this is an umbrella term comprising heterogeneous vascular disorders, each with disparate pathophysiology and prognosis.
Rahman, H., Hoole, S.P., Channon, K., UK Coronary Microvascular Dysfunction Working Group, Morris, Paul D, Kharbanda, Rajesh K, Divaka Perera, Channon, K, Petraco, Ricardo, Haseeb Rahman, Hoole, SP, Perera, D., Sinha, Aish, Ricardo Petraco, Keith Channon, Colin Berry, Paul D Morris, Channon, Keith, Stephen P Hoole, Morris, P.D., Hoole, Stephen P, Rajesh K Kharbanda, Rahman, Haseeb, Kharbanda, RK, Hoole, Stephen P., Kharbanda, R.K., Aish Sinha, Petraco, R, Kharbanda, Rajesh K., Perera, Divaka, Sinha, A., Morris, Paul D., Berry, Colin, Berry, C, Morris, PD, Berry, C., Perera, D, Sinha, A, Petraco, R., Rahman, H   +39 more
core   +1 more source

Systematic Cardiac Phenotyping of Patients With Copy Number Variants in the 15q11.2 Breakpoint 1 to Breakpoint 2 Region: A Retrospective Cohort Study From Nine Pediatric Cardiac Centers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Microdeletions impacting 15q11.2 breakpoint (BP) 1 to BP2, adjacent to the Prader–Willi critical region, have previously described neuropsychiatric associations, with potential low penetrance presentations of congenital heart disease (CHD) also identified.
Morgan B. Wright, Maria B. Padua, Lindsey R. Helvaty, Kim L. McBride, Gabrielle Geddes, Vidu Garg, Seema R. Lalani, Stephanie Burns Wechsler, Jennelle C. Hodge, Benjamin J. Landis, Stephanie M. Ware   +10 more
wiley   +1 more source

Coronary arteries variants & congenital anomalies; using MDCT to assess their preval

The Egyptian Journal of Radiology and Nuclear Medicine, 2015
Objectives: To display the prevalence rate of the coronary artery anatomical variations & congenital anomalies in 1000 patients of the Egyptian population using multidetector computed tomography (MDCT) exhibiting its diagnostic capability.
Sherif Fathy Abdelrahman, Mohamed Ali Salem, Nahla Deyaa Eldeen Mostafa, Abo Elmagd Mohamed Elbohy   +3 more
doaj   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

The Importance of Echocardiography in Detecting Coronary Artery Anomalies in Children

Journal of Behçet Uz Children's Hospital, 2020
INTRODUCTION: There is no established current algorithm of treatment and clinical follow-up in children with coronary artery anomalies. We analysed the clinical characteristics, diagnosis treatment options of children and adolescents identified with ...
Tülay Demircan, Baris Guven, Cem Karadeniz, Ali Rahmi Bakiler, Dilek Oncel, Nazmi Narin   +5 more
doaj   +1 more source

Leveraging Big Multitemporal Multisource Satellite Data and Artificial Intelligence for the Detection of Complex and Invisible Features: The Case of Extensive Irrigation Mapping

Archaeological Prospection, EarlyView.
ABSTRACT The detection of buried or obscured archaeological features remains a central challenge in landscape archaeology, particularly in the irrigated floodplains of Mesopotamia where levees and canals formed the basis of complex agrarian systems. This study presents a deep learning–based approach for the large‐scale, automated detection of ancient ...
Nazarij Buławka, Hector A. Orengo, Felipe Lumbreras Ruiz, Iban Berganzo‐Besga, Ekta Gupta   +4 more
wiley   +1 more source