Results 111 to 120 of about 196,937 (317)

The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes:the MRC-ILA Heart Study [PDF]

, 2014
AIMS: Acute coronary syndromes (ACSs) are driven by inflammation within coronary plaque. Interleukin-1 (IL-1) has an established role in atherogenesis and the vessel-response to injury. ACS patients have raised serum markers of inflammation.
Greenwood, J.P., Hall, Alistair S., Rothman, A.M.K., Morton, Allison C., Foley, C., Chase, A., Greenwood, John P, Chase, Alex, Morton, Allison C, Wang, Duolao, Rothman, Alexander M K, Banya, Winston, Clarke, B., Gunn, J., Crossman, David C, Rothman, Alexander M. K., Crossman, David C., Flather, Marcus D, Rothman, Alexander M.K., Clarke, Bernard, Fox, Keith, Fox, K., Banya, W., Hall, Alistair S, Gunn, Julian, Flather, Marcus D., Greenwood, John P., Foley, Claire, Hall, A.S., Morton, A.C.   +29 more
core   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Effects of Endogenous Androgens on Pulmonary Microvascular Reactivity

, 2007
Previous studies involving large isolated pulmonary arteries have suggested that the administration of high concentrations of natural androgen produces acute vasodilation. This study examines the acute effects of testosterone (T) and dihydrotestosterone (
Dells, James D.
core  

Coronary Artery Anomalies

, 2023
My thesis is on coronary artery anomalies in the past 10 clinical years. It covers what coronary artery anomalies are themselves, their prevalence in the population, the clinical relevance, and ways to detect and treat them.LBáltalános orvosangolegységes,
Khan, Ehsan Asad
core  

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Pulmonary artery from the left main coronary artery

Annals of Pediatric Cardiology, 2019
The usual sources of pulmonary blood flow in pulmonary atresia (PA) with(VSD) are patent ductus arteriosus and aortopulmonary collaterals. However, rarely fistulous collaterals may also arise from the coronary arteries which usually open into the main ...
Raghav Bansal, Sivasubramanian Ramakrishnan, Sunil Kumar Verma   +2 more
doaj   +1 more source

Coronary artery remodelling [PDF]

Heart, 1998
Intravascular ultrasound shows that many coronary artery atherosclerotic plaques do not encroach on the lumen and therefore are angiographically invisible.1 2 The reason for this phenomenon was first firmly established in human coronary arteries by Glagov and colleagues.3 As a plaque develops the overall cross sectional area of the coronary artery ...
openaire   +2 more sources

Circulating humoral factors and endothelial progenitor cells in patients with differing coronary collateral support

, 2004
Background - The mechanisms underlying the variation in collateral formation between patients, even with similar patterns of coronary artery disease, remain unclear.
Bucknall, CA, Meng, Y G, Redwood, SR, Pearson, JD, Redwood, S R, Edwards, R J, Lambiase, PD, Marber, MS, Edwards, RJ, Anthopoulos, P, Rahman, S, Lambiase, P D, Meng, YG, Pearson, J D, Marber, M S; id_orcid, Bucknall, C A   +15 more
core   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source