Results 121 to 130 of about 1,806,820 (366)

Lumen Diameter of Normal Human Coronary Arteries: Influence of Age, Sex, Anatomic Variation, and Left Ventricular Hypertrophy or Dilation

Circulation, 1992
BackgroundPrecise knowledge of the expected “normal” lumen diameter at a given coronary anatomic location is a first step toward developing a quantitative estimate of coronary disease severity that could be more useful than the traditional “percent ...
J T Dodge, B. G. Brown, E. Bolson, H. Dodge   +3 more
semanticscholar   +1 more source

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, EarlyView.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

Investigation the Effect of Velocity inlet and Carrying Fluid on the Flow inside Coronary Artery [PDF]

arXiv, 2021
In this study OpenFOAM 4.4.2 was used to investigate flow inside the coronary artery of the heart. This step is the first step of our future project, which is to include conjugate heat transfer of the heart with three main coronary arteries. Three different velocities were used as inlet boundary conditions to see the effect of velocity increase on ...
arxiv  

Association between adiposity and systemic atherosclerosis: a protocol of a cross-sectional autopsy study. [PDF]

, 2016
IntroductionAdiposity has been associated with atherosclerosis in clinical studies. However, few autopsy studies have investigated this association, and they had only examined the coronary artery disease. Moreover, most studies had small sample sizes and
Campos, Fernanda Marinho, Cuelho, Anderson, da Silva, Karen Cristina Souza, Farfel, José Marcelo, Farias, Daniela Souza, Ferretti-Rebustini, Renata Eloah de Lucena, Grinberg, Lea Tenenholz, Jacob-Filho, Wilson, Leite, Renata Elaine Paraízo, Nishizawa, Aline, Pasqualucci, Carlos Augusto, Suemoto, Claudia Kimie   +11 more
core   +2 more sources

Imaging of Inflamed and Vulnerable Plaque in Coronary Arteries with 18F-FDG PET/CT in Patients with Suppression of Myocardial Uptake Using a Low-Carbohydrate, High-Fat Preparation

Journal of Nuclear Medicine, 2009
PET/CT imaging with 18F-FDG has been used to detect inflammation in carotid and aortic plaque; its use in detecting coronary plaque has been limited by avid 18F-FDG uptake by the myocardium.
J. Wykrzykowska, S. Lehman, Gethin Williams, J. Parker, M. Palmer, S. Varkey, G. Kolodny, R. Laham   +7 more
semanticscholar   +1 more source

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

The relationship between mechanical dyssynchrony of the left ventricular myocardium and the number of affected coronary arteries in patients with coronary heart disease who underwent revascularization

Journal of V. N. Karazin Kharkiv National University: Series Medicine
Background. A promising method for early detection of myocardial dysfunction is the evaluation of mechanical dyssynchrony of the left ventricular myocardium, the prognostic value of which in the diagnosis of 3-vessel lesions was shown only in a single ...
Barat kyzy Mehtieva Fatma, O.V. Bilchenko   +1 more
doaj   +1 more source

Anatomical variants and coronary anomalies detected by dual-source coronary computed tomography angiography in North-eastern Thailand [PDF]

, 2018
Purpose: Congenital coronary anomalies are uncommon, with an incidence ranging from 0.17% in autopsy cases to 1.2% in angiographically evaluated cases. The recent development of dual-source coronary computed tomography angiography (coronary CTA) allows ...
Chaosuwannakit, Narumol
core   +1 more source

Experimental Subendocardial Ischemia in Dogs with Normal Coronary Arteries

Circulation Research, 1972
Subendocardial ischemia without anatomic coronary artery obstruction may result from a discrepancy between metabolic needs and available blood supply. We studied this in open-chest anesthetized dogs and measured pressures in aorta and left ventricle (LV),
G. Buckberg, D. Fixler, J. Archie, J. Hoffman   +3 more
semanticscholar   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source