Results 91 to 100 of about 511,877 (268)

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source

Factors Related to Knowledge, Health Belief and Sick Role Behavior to the Coronary Artery Disease among Patients with Coronary Artery Disease [PDF]

, 2011
Youngok Kang, Young-Chae Cho
openalex   +1 more source

Myocardial Infarction with Nonobstructive Coronary Artery Disease—Definition, Etiopathogenesis, Diagnosis, and Management

, 2021
Patrick Baghdasaryan, Balaji Natarajan, Madlena Nalbandian, Padmini Varadarajan, Ramdas G. Pai   +4 more
openalex   +2 more sources

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

Comparison of intravascular lithotripsy versus rotational atherectomy for the treatment of severe coronary artery calcification

BMC Cardiovascular Disorders
Background Calcified lesions are one of the most challenging cases for PCI, where optimal angiographic results and satisfying outcomes are hard to achieve.
Yuhao Zhao, Ping Wang, Ze Zheng, Yuchen Shi, Jinghua Liu   +4 more
doaj   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Celastrol improves endothelial function in diet-induced obesity mice via attenuating endoplasmic reticulum stress through the activation of AMPK pathway

Molecular Medicine
Background Diet-induced obesity (DIO) is a significant factor in endothelial dysfunction. Celastrol, a potent anti-inflammatory and anti-oxidative pentacyclic triterpene, has shown promise as a protective agent against cardiovascular disease.
Cheng Yu, Weihong Lin, Jing Yang, Qiong Jiang, Wenkun Liu, Hongjin Liu, Yong Lin, Litao Wang, Lei Chen, Yu Huang, Lianglong Chen   +10 more
doaj   +1 more source

Miscues on the "lack of MEF2A mutations" in coronary artery disease [PDF]

, 2005
Qing Wang
openalex   +1 more source

Deep Learning Model for Predicting Operative Mortality After Total Gastrectomy: Analysis of the Japanese National Clinical Database (NCD)

Annals of Gastroenterological Surgery, EarlyView.
Deep learning‐based prediction model for operative mortality using the National Clinical Database (NCD). The model achieved a C‐statistic of 0.74. ABSTRACT Background Radical gastrectomy with lymph node dissection is the primary treatment for gastric cancer.
Ryosuke Fukuyo, Hiroyuki Yamamoto, Masanori Tokunaga, Yusuke Kinugasa, Yoshihiro Kakeji, Ken Shirabe   +5 more
wiley   +1 more source

Simulation training significantly improves the performance of novice students achieving the standard transesophageal echocardiography views

BMC Medical Education
Background Transesophageal echocardiography (TEE) is an important cardiovascular imaging modality, offering detailed images surpassing other techniques, including transthoracic echocardiography.
Aleksander Siniarski, Paweł Piątek, Aleksandra Karcińska, Alicia del Carmen Yika, Kamil Szostek, Tomasz Dziwiński, Maciej Stąpór, Karolina Golińska-Grzybała, Adam Piórkowski, Andrzej Gackowski   +9 more
doaj   +1 more source