Results 111 to 120 of about 1,108,368 (374)

Genomewide association analysis of coronary artery disease.

New England Journal of Medicine, 2007
BACKGROUND Modern genotyping platforms permit a systematic search for inherited components of complex diseases. We performed a joint analysis of two genomewide association studies of coronary artery disease. METHODS We first identified chromosomal loci
N. Samani, J. Erdmann, A. Hall, C. Hengstenberg, M. Mangino, Bjoern Mayer, R. Dixon, T. Meitinger, P. Braund, H. Wichmann, J. Barrett, I. König, Suzanne E Stevens, S. Szymczak, D. Tregouet, M. Iles, F. Pahlke, Helen Pollard, W. Lieb, F. Cambien, M. Fischer, W. Ouwehand, S. Blankenberg, A. Balmforth, A. Baessler, S. Ball, T. Strom, I. Braenne, C. Gieger, P. Deloukas, M. Tobin, A. Ziegler, J. Thompson, H. Schunkert   +33 more
semanticscholar   +1 more source

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

PAF‐induced inflammatory and immuno‐allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects

BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022
Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley   +1 more source

Coronary Artery Disease Research in India: A Scientometric Assessment of Publication during 1990-2019 [PDF]

arXiv, 2021
The present study examined 4698 Indian Coronary Artery Disease research publications, as indexed in Web of Science database during 1990-2019, with a view to understand their growth rate, global share, citation impact, international collaborative papers, distribution of publications by broad subjects, productivity and citation profile of top ...
arxiv  

Dysbiosis signatures of gut microbiota in coronary artery disease.

Physiological Genomics, 2018
Gut microbiota dysbiosis has been considered to be an important risk factor that contributes to coronary artery disease (CAD), but limited evidence exists about the involvement of gut microbiota in the disease.
Qi Zhu, R. Gao, Yi Zhang, Dengdeng Pan, Yefei Zhu, Xiaohui Zhang, Rong Yang, Rong-zhen Jiang, Yawei Xu, H. Qin   +9 more
semanticscholar   +1 more source

Coronary artery disease in women

Australian Prescriber, 2022
Cardiovascular disease is the leading global cause of death in women but remains underdiagnosed and undertreated. Health professionals play an important role in improving the heart health of Australian women. Routine heart health checks should be offered to all women 45 years of age and older and to all Aboriginal and Torres Strait Islander women 30 ...
Montarello, Natalie, Chan, Wai Ping (Alicia)   +1 more
openaire   +2 more sources

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

Long‐term outcomes after paclitaxel‐coated balloon angioplasty of femoropopliteal arteries in Asian patients of the IN.PACT Global Study

Catheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1273-1283, December 1, 2022., 2022
Abstract Objectives The long‐term data on the use of drug‐coated balloons (DCBs) for femoropopliteal atherosclerotic lesions in the real‐world setting are limited, even more so for racially and geographically distinct populations. The present analysis reports the 5‐year safety and effectiveness outcomes of a DCB in the Asian subset of the prospective ...
Young‐Guk Ko, Donghoon Choi, Seung‐Woon Rha, Je Hwan Won, Young‐Soo Do, Seung‐Whan Lee, Jeremiah S. Menk, Steven Kum   +7 more
wiley   +1 more source

Computed tomography coronary angiogram images, annotations and associated data of normal and diseased arteries [PDF]

arXiv, 2022
Computed Tomography Coronary Angiography (CTCA) is a non-invasive method to evaluate coronary artery anatomy and disease. CTCA is ideal for geometry reconstruction to create virtual models of coronary arteries. To our knowledge there is no public dataset that includes centrelines and segmentation of the full coronary tree.
arxiv  

Impaired coronary blood flow at higher heart rates during atrial fibrillation: investigation via multiscale modelling [PDF]

Computer Methods and Programs in Biomedicine, 175: 95-102, 2019, 2019
Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the present work is to computationally explore whether and to what extent ventricular rate during AF affects the ...
arxiv   +1 more source