Results 131 to 140 of about 5,756,266 (314)

Twenty‐Four‐Hour Blood Pressure Variability Combined With Circadian Rhythm Patterns in Predicting Cardiovascular Events in Hypertensive Patients

The Journal of Clinical Hypertension
Short‐term blood pressure variability (BPV) and circadian BP abnormalities are important cardiovascular risk predictors of mean BP levels, but their combined prognostic significance in essential hypertension remains incompletely understood.
Qin Ma, Shaoping Wang, Hua Chen
doaj   +1 more source

Carotid artery disease screening : assessment of criteria [PDF]

, 1996
The Department of Radiology at St. Luke’s Hospital has provided a screening service for stroke related disease since April 1991. This consisted of Duplex Ultrasound screening (DUS) for Extracranial Carotid Artery Disease (ECAD) followed by angiography or
Galea Debono, Anthony, Zammit, Anthony, Gatt, Alexander   +2 more
core  

Expression of monocyte and lymphocyte adhesion molecules is increased in isolated coronary artery ectasia

, 2007
Background Coronary artery ectasia is defined as localized or diffuse dilation of the coronary arteries exceeding the 1.5-fold of normal adjacent segment. Scarce data are available about the role of inflammation in coronary artery ectasia. In the present
Yildirim, Nesligul, Dogan, Sait M., Gursurer, Metin, Akoz, Ayla, Aydin, Mustafa, Cam, Fatih, Gungorduk, Alper, Tekin, Ishak O.   +7 more
core   +1 more source

Salvianolic Acid a Disrupts the HSP90α‐AKT‐PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan, Mengkai Lu, Xinhai Cui, Dawei Zhang, Lei Zhang, Lin Lin, Yuan Li, Yuanlong Hu, Chao Li   +8 more
wiley   +1 more source

Inflammatory markers guide early risk stratification and prognosis in elderly patients with acute myocardial infarction

Scientific Reports
High-sensitivity C-reactive protein (hs-CRP) has been associated with prognosis in acute myocardial infarction (AMI) patients, but data on its role in elderly individuals remains limited.
XiaoLong Lin, Qian Fan, QiuYu Li, XiaoWen Bo, SiYuan Chen, XiaoFan Wu   +5 more
doaj   +1 more source

Pharmacological treatment of coronary artery disease

, 2022
This thesis highlights an overview of the epidemiology, risk factors, pathomechanism and diagnosis, with special attention to pharmacological strategies involved in the treatment of CAD.
Adamoh, Hasbiallah Oluwatobi
core  

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

Advanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu, Zichao Huang, Xi Rong, Xingwei Lei, Fuming Liang, Xiaoguo Li, Jiru Zhou, Yu Wang, Yifan Huang, Shuang Tang, Jianjun Zhong, Jin Yan, Hongji Deng, Chun Zeng, Zongduo Guo   +14 more
wiley   +1 more source

Efficacy and safety of drug-coated balloons in chronic total coronary occlusion recanalization: a systematic review and meta-analysis

BMC Cardiovascular Disorders
Background With advancements in chronic total coronary occlusion (CTO) recanalization techniques and concepts, the success rate of recanalization has been steadily increasing.
Yuhao Zhao, Ping Wang, Ze Zheng, Qin Ma, Yuchen Shi, Jinghua Liu   +5 more
doaj   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

Are percutaneous coronary interventions changing our coronary surgery practice? [PDF]

, 2010
Aim: The aim of this retrospective study was to assess the impact of a growing percutaneous coronary intervention (PCI) program on our coronary artery bypass graft (CABG) practice.
Manche, Alexander, Casha, Aaron
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