Results 151 to 160 of about 5,756,266 (314)

Cardiovascular regulation and vascular structure in prehypertension and coronary heart disease [PDF]

open access: yes, 2009
The aim of this thesis was to characterize vascular structure and different aspects of cardiovascular regulation in otherwise healthy subjects with slightly elevated blood pressure and compare to healthy subjects with normotension and also investigate ...
Myredal, Anna
core  

Sex-related differences in the angiographic results of 14,500 cases referred for suspected coronary artery disease

open access: yes, 2008
OBJECTIVE: To investigate sex differences of angiographic results in patients undergoing coronary angiography for suspected coronary artery disease (CAD). METHODS: We retrospectively assessed the coronary angiograms of 2840 women and 11,610 men from 1984
Giannoglou, George D.   +5 more
core   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun   +7 more
wiley   +1 more source

Effect of Extended Dual Antiplatelet Therapy on the Prognosis of Patients With ST Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention: A Retrospective Cohort Study

open access: yesHealth Science Reports
Background and Aims To inquire the effect of extending the duration of dual antiplatelet therapy (DAPT) to 18–24 months on the prognosis of patients with ST segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention ...
Ya‐chao Li   +7 more
doaj   +1 more source

The primary and secondary prevention of coronary artery disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

open access: yes, 2008
The following chapter devoted to antithrombotic therapy for chronic coronary artery disease (CAD) is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition ...
Mark, Daniel B   +8 more
core   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert   +31 more
wiley   +1 more source

Coronary artery bypass surgery in the elderly : is it worthwhile? [PDF]

open access: yes, 2013
Objectives: To evaluate the early outcomes after coronary surgery in the elderly. Methods: A retrospective analysis (April 1995- January 2012) of mortality, morbidity and hospital stay, derived from a single surgeon’s practice.
Manche, Alexander
core  

Systematic Cardiac Phenotyping of Patients With Copy Number Variants in the 15q11.2 Breakpoint 1 to Breakpoint 2 Region: A Retrospective Cohort Study From Nine Pediatric Cardiac Centers

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Microdeletions impacting 15q11.2 breakpoint (BP) 1 to BP2, adjacent to the Prader–Willi critical region, have previously described neuropsychiatric associations, with potential low penetrance presentations of congenital heart disease (CHD) also identified.
Morgan B. Wright   +10 more
wiley   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou   +4 more
wiley   +1 more source

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