Results 151 to 160 of about 1,563,252 (400)

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

Advanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang   +9 more
wiley   +1 more source

In Vivo Dynamic Coronary Arteries Blood Flow Imaging Based on Multi‐Cycle Phase Clustering Ultrafast Ultrasound

Advanced Science, EarlyView.
This study addresses a critical gap in ultrafast ultrasound cardiovascular flow imaging and introduces a transformative approach, Clustering Singular Value Decomposition (cSVD), which enables dynamic cardiovascular flow imaging throughout full cardiac cycle without motion correction and hyper‐fast imaging strategies.
Hao Yu, Jiabin Zhang, Feng Feng, Jinyu Yang, Yu Xia, Yunlong Zhao, Jue Zhang   +6 more
wiley   +1 more source

Cholesterol, Cholesterol Esters and Phospholipids in Health and in Coronary Artery Disease [PDF]

, 1950
Menard M. Gertler, Stanley M. Garn, Howard B. Sprague   +2 more
openalex   +1 more source

Depression in Coronary Artery Disease

Journal of cardiovascular and thoracic research, 2012
Introduction: Depression is one of the Common psychological disorders. From the cognitive point of view, the unhealthy attitudes increase the severity of the depression. The aim of this study was to investigate depression and unhealthy attitudes in coronary patients hospitalized at Tabriz Shahid Madani Heart Center.
Majid Khalili, Ahmadreza Jodati, Nasser Safaie, Mohammad Bager Raoofi   +3 more
openaire   +4 more sources

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source

Comparison of intravascular lithotripsy versus rotational atherectomy for the treatment of severe coronary artery calcification

BMC Cardiovascular Disorders
Background Calcified lesions are one of the most challenging cases for PCI, where optimal angiographic results and satisfying outcomes are hard to achieve.
Yuhao Zhao, Ping Wang, Ze Zheng, Yuchen Shi, Jinghua Liu   +4 more
doaj   +1 more source

UNDERNUTRITION IN THE TREATMENT OF CORONARY ARTERY DISEASE (PARTICULARLY THROMBOSIS). EFFECT ON THE BASAL METABOLISM AND CIRCULATION 1 [PDF]

, 1936
Arthur M. Mastér, Harry L. Jaffe, Simon Dack   +2 more
openalex   +1 more source

Preface and Acknowledgement [PDF]

, 2014
Background. The choice of treatment strategy for coronary artery disease is often based on: 1) anatomical information on stenosis locations, and 2) functional information on their haemodynamic relevance, e.g.
Babic, Aleksandar, Bulatovic, Ivana, Giesecke, Anders, Larsson, Matilda, Nordenfur, Tim, Ripsweden, Jonaz, Samset, Eigil, Winter, Reidar   +7 more
core   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Celastrol improves endothelial function in diet-induced obesity mice via attenuating endoplasmic reticulum stress through the activation of AMPK pathway

Molecular Medicine
Background Diet-induced obesity (DIO) is a significant factor in endothelial dysfunction. Celastrol, a potent anti-inflammatory and anti-oxidative pentacyclic triterpene, has shown promise as a protective agent against cardiovascular disease.
Cheng Yu, Weihong Lin, Jing Yang, Qiong Jiang, Wenkun Liu, Hongjin Liu, Yong Lin, Litao Wang, Lei Chen, Yu Huang, Lianglong Chen   +10 more
doaj   +1 more source