Results 271 to 280 of about 408,546 (351)

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Inter-arm Blood Pressure Difference is Associated With Both Coronary Artery Disease and Peripheral Artery Disease in People With HIV. [PDF]

Open Forum Infect Dis
Amaral S, Suarez-Zdunek MA, Knudsen AD, Larsen AF, Borges ÁH, Køber LV, Benfield T, Kofoed KF, Brites C, Nielsen SD.   +9 more
europepmc   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

IUM-hybrid model for enhanced CAD diagnosis using deep learning and VS Grad-CAM visualization. [PDF]

Sci Rep
Revathi CK, Santhi H.
europepmc   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Relationship between C-reactive protein-to-albumin ratio and new-onset coronary artery disease and its severity in different glucose metabolic states: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Han S, Chen L, Shu H, Zhao G, Zhang H, Li J, Qiu W, Cheng J, Zheng G, Li Q.   +9 more
europepmc   +1 more source

Do We Really Know How to Manage Anticoagulated Patients for Periodontal Nonsurgical Therapy? An Observational Cohort Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives The aim of this work is to assess and compare the impact of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKA) during and immediately after periodontal nonsurgical therapy. Materials and Methods A prospective observational cohort study was conducted with patients who presented a history of cardiovascular disease ...
F. Berton, A. Rapani, F. Costantinides, V. Nicolin, D. Cuhureanu, R. Di Lenarda   +5 more
wiley   +1 more source

Self-Reported Habitual Daily Physical Activity as an Independent Predictor of Coronary Artery Disease Extension in Patients with Myocardial Infarction: A Prospective Observational Study. [PDF]

J Clin Med
Cinezan C, Hiceag ML.
europepmc   +1 more source

Reference Values for Pulse Oximetry Testing in Permanent Teeth: A Systematic Review and Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Pulse oximetry is an accurate diagnostic method for assessing the condition of the dental pulp; however, the normal oxygen saturation levels for each tooth type are yet to be clearly defined. Objectives This systematic review and meta‐analysis aims to answer the question: What are the reference values for pulse oximetry testing in ...
Lilian Tietz, Theodoro Weissheimer, Cassiano Kuchenbecker Rösing, Marcus Vinicius Reis Só   +3 more
wiley   +1 more source

Omentin-1 Val109Asp polymorphism and increased coronary artery disease risk in smokers with type 2 diabetes. [PDF]

Medicine (Baltimore)
Yu D, Tong L, Ma X, Gu N, Lu D, Yu N, Wang Y, Zhang J, Li J, Guo X.   +9 more
europepmc   +1 more source