Results 81 to 90 of about 408,546 (351)

The validity and applicability of CAD-RADS in the management of patients with coronary artery disease [PDF]

Insights into Imaging, 2019
Abstract Background The coronary artery disease reporting and data system (CAD-RADS) is designed for a uniform standardization of coronary computed tomography angiography (CCTA) reporting and further management recommendations of coronary artery disease (CAD).
Mohammad Abd Alkhalik Basha, Sameh Abdelaziz Aly, Ahmad Abdel Azim Ismail, Hanan A. Bahaaeldin, Said A. Shehata   +4 more
openaire   +3 more sources

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease

Circulation Research, 2017
Rationale: Coronary artery disease (CAD) is a complex phenotype driven by genetic and environmental factors. Ninety-seven genetic risk loci have been identified to date, but the identification of additional susceptibility loci might be important to ...
P. van der Harst, N. Verweij
semanticscholar   +1 more source

Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]

, 2001
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Virók Dezső, Gönczöl Éva, Prohászka Zoltán, Burián, Katalin, Endrész Valéria, Duba Jenő, Füst György, Kis, Zoltán, Virók, Dezső, Endrész, Valéria, Duba, Jenő, Boda, Krisztina, Berencsi Klára, Berencsi, Klára, Kis Zoltán, Romics, László, Romics László, Gönczöl, Éva, Prohászka, Zoltán, Horváth, Laura, Boda Krisztina, Burián Katalin, Horváth Laura, Füst, György   +23 more
core   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

CAD-RADS: A Standardized Reporting System for Coronary CT Angiography

Journal of the Korean Society of Radiology
Coronary CT angiography (CTA) has been firmly established as a reliable and accurate noninvasive diagnostic modality for the evaluation of coronary artery disease (CAD).
Jin Hur, Yoo Jin Hong
doaj   +1 more source

The I allele of the angiotensin converting enzyme I/D polymorphism confers protection against coronary artery disease

, 2017
Background: Mutations in genes regulating lipid metabolism, vasoactivity, and coagulation are important modulators of coronary artery disease (CAD).
Sawaya, Jaber, Zalloua, Pierre A., Hanine, Estephan, Rebeiz, Abdallah G., Puzantian, Houry, Abchee, Antoine, Youhanna, Sonia, El-Sibai, Mirvat, Makhoul, Nadine J., Yeretzian, Joumana S., Zreik, Tony G., Nasrallah, Antoine, Azar, Sami T.   +12 more
core   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Japan Implantable Devices in Coronary Artery Disease (JID‐CAD) study design [PDF]

Journal of Arrhythmia, 2014
AbstractBackgroundThere is little information regarding appropriate therapies for coronary artery disease (CAD) patients with implantable devices – such as implantable cardioverter‐defibrillators (ICDs), cardiac resynchronization therapy devices (CRT‐Ds) and cardiac resynchronization therapy pacemaker (CRT‐P) devices – in Japan. To address this lack of
Akihiko Shimizu, M.D., Ph.D., FACC, Takeshi Mitsuhashi, Takashi Nitta, Hideo Mitamura, Takashi Kurita, Haruhiko Abe, Yuji Nakazato, Naokata Sumitomo, Kazushige Kadota, Kazuo Kimura, Ken Okumura   +10 more
openaire   +3 more sources

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Nature Genetics, 2015
Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association study (GWAS) analysis of common SNPs.
M. Nikpay, A. Goel, H. Won, Leanne M. Hall, C. Willenborg, S. Kanoni, D. Saleheen, T. Kyriakou, C. Nelson, J. Hopewell, T. Webb, Lingyao Zeng, A. Dehghan, Maris Alver, Sebastian M. Armasu, K. Auro, A. Bjonnes, D. Chasman, Shufeng Chen, I. Ford, N. Franceschini, C. Gieger, C. Grace, S. Gustafsson, Jie Huang, Shih-Jen Hwang, Y. Kim, M. Kleber, K. Lau, Xiangfeng Lu, Yingchang Lu, L. Lyytikäinen, E. Mihailov, A. Morrison, N. Pervjakova, L. Qu, L. Rose, Elias L Salfati, R. Saxena, M. Scholz, A. Smith, E. Tikkanen, A. Uitterlinden, Xueli Yang, Weihua Zhang, Wei Zhao, M. de Andrade, P. D. de Vries, Natalie R. van Zuydam, Sonia S Anand, L. Bertram, F. Beutner, G. Dedoussis, P. Frossard, D. Gauguier, A. Goodall, O. Gottesman, Marc Haber, B. Han, Jianfeng Huang, S. Jalilzadeh, T. Kessler, I. König, L. Lannfelt, W. Lieb, L. Lind, C. Lindgren, M. Lokki, P. Magnusson, N. H. Mallick, N. Mehra, T. Meitinger, Fazal-ur-rehman Memon, A. Morris, M. Nieminen, N. Pedersen, A. Peters, L. Rallidis, A. Rasheed, M. Samuel, Svati H. Shah, J. Sinisalo, K. Stirrups, S. Trompet, Laiyuan Wang, K. S. Zaman, D. Ardissino, E. Boerwinkle, I. Borecki, E. Bottinger, J. Buring, J. Chambers, R. Collins, L. Cupples, J. Danesh, I. Demuth, R. Elosúa, S. Epstein, T. Esko, M. Feitosa, O. Franco, M. Franzosi, C. Granger, D. Gu, V. Gudnason, A. Hall, A. Hamsten, T. Harris, S. Hazen, C. Hengstenberg, A. Hofman, E. Ingelsson, C. Iribarren, J. Jukema, P. Karhunen, Bong-Jo Kim, J. Kooner, I. Kullo, T. Lehtimäki, R. Loos, O. Melander, A. Metspalu, W. März, C. Palmer, M. Perola, T. Quertermous, D. Rader, P. Ridker, S. Ripatti, R. Roberts, V. Salomaa, D. Sanghera, S. Schwartz, U. Seedorf, A. Stewart, D. Stott, J. Thiery, P. Zalloua, C. O’Donnell, M. Reilly, T. Assimes, J. Thompson, J. Erdmann, R. Clarke, H. Watkins, S. Kathiresan, R. McPherson, P. Deloukas, H. Schunkert, N. Samani, M. Farrall   +150 more
semanticscholar   +1 more source

Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen risk and cardiovascular health study)

, 2009
Background Heme oxygenase-1 is an inducible cytoprotective enzyme which handles oxidative stress by generating anti-oxidant bilirubin and vasodilating carbon monoxide.
Hoffmann Michael M, Hoffmann, Michael Marcus, März Winfried, Boehm Bernhard O, Wellnitz Britta, Karl Winkler, Bernhard O Boehm, Bernhard R Winkelmann, März, Winfried, Winkelmann Bernhard R, Winkler Karl, Hoffmann, Michael M., Seelhorst Ursula, Ursula Seelhorst, Seelhorst, Ursula, Britta Wellnitz, Böhm, Bernhard O., Böhm, Bernhard Otto, Michael M Hoffmann, Lüblinghoff Nicola, Lüblinghoff, Nicola, Winkelmann, Bernhard Rudolf, Winfried März, Winkler, Karl, Nicola Lüblinghoff, Winkelmann, Bernhard R., Wellnitz, Britta   +26 more
core   +1 more source