Results 111 to 120 of about 981,607 (247)

Decoding Coronary Collateral Circulation: Predictive Value of the Systemic Immune-Inflammation Index

Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College
Objective: The current study was designed to determine the association between the Systemic Immune-Inflammation Index (SII) and the degree of coronary collateral circulation in patients with stable coronary artery disease.
SHAZIA NAZAR, Muhammad Tanveer Alam, Mozaffer Rahim Hingorjo, Sumaira Riffat, Muhammad Khalid Siddiqui, Zainab Askari   +5 more
doaj   +1 more source

Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma

Advanced Science, EarlyView.
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul, Alexandra Moreno Mitchell, Dean O'Neil, Yutong Luo, Khuloud T. Al‐Jamal   +4 more
wiley   +1 more source

Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues

Advanced Science, EarlyView.
Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali, Mangirdas Malinauskas, Giuseppe Chirico   +2 more
wiley   +1 more source

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

Advanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

Underuse of coronary revascularization procedures in patients considered appropriate candidates for revascularization. [PDF]

, 2001
Background: Ratings by an expert panel of the appropriateness of treatments may offer better guidance for clinical practice than the variable decisions of individual clinicians, yet there have been no prospective studies of clinical outcomes. We compared
Feder, G, Dawson, JR, Timmis, AD, Wood, A, Sanders, J, Crook, AM, Hemingway, H, Magee, P, Banerjee, S, Philpott, S   +9 more
core  

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Relationship of coronary collateral circulation with eosinophils in patients with unstable angina pectoris

, 2016
Jun Wang,1,* Qun Li,2,* Shi-jing Li,1 De-zhao Wang,2 Bu-xing Chen2 1Department of Cardiology, Beijing Mentougou District Hospital, 2Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China
Wang DZ, Chen BX, Li SJ, Li Q, Wang J
core  

Does autonomic function link social position to coronary risk? The Whitehall II study. [PDF]

, 2005
BACKGROUND: Laboratory and clinical studies suggest that the autonomic nervous system responds to chronic behavioral and psychosocial stressors with adverse metabolic consequences and that this may explain the relation between low social position and ...
Shipley, M, Britton, A, Malik, M, Brunner, E, Marmot, M, Hemingway, H   +5 more
core  

The primary and secondary prevention of coronary artery disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

, 2008
The following chapter devoted to antithrombotic therapy for chronic coronary artery disease (CAD) is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition ...
Mark, Daniel B, Harrington, Robert A, Ezekowitz, Michael, Vorchheimer, David A, O'Connor, Christopher M, Meade, Thomas W, Guyatt, Gordon H, Becker, Richard C, Berger, Peter B   +8 more
core   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source