Results 161 to 170 of about 11,009,796 (379)

Effect of Evolocumab on Progression of Coronary Disease in Statin-Treated Patients: The GLAGOV Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2016
S. Nicholls, R. Puri, T. Anderson, C. Ballantyne, L. Cho, J. Kastelein, W. Koenig, R. Somaratne, H. Kassahun, Jingyuan Yang, S. Wasserman, R. Scott, I. Ungi, J. Podolec, A. O. Ophuis, J. Cornel, Marilyn Borgman, D. Brennan, S. Nissen   +18 more
semanticscholar   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

Association between IL-2 Receptor and Severe Coronary Artery Calcification in Patients with Coronary Artery Disease

Reviews in Cardiovascular Medicine
Background: Coronary artery calcification (CAC) is a crucial marker for coronary atherosclerosis, and the extent of CAC is closely linked to the incidence and progression of cardiovascular diseases.
Chenyang Wang, Sheng Liu, Raimov Kamronbek, Siyao Ni, Kexin Yang, Yunxiao Yang, Daliang Zhou, Can Zhou, Chengqian Yin, Ming Zhang   +9 more
doaj   +1 more source

White Blood Cell/Mean Platelet Volume Ratio as a Predictor of Long-Term Outcomes but Not Coronary Artery Disease Severity in Non-ST Elevation Myocardial Infarction Patients [PDF]

, 2023
Gizem Demir, Gürkan Karaca, Ahmet Ekmekçi, Seyedehtina Safaei, Ali Kimiaei, Ayşe Emre   +5 more
openalex   +1 more source

Tie2‐Dependent Mechanisms Influence Leptomeningeal Collateral Dynamics and Reperfusion Following Stroke

Advanced Science, EarlyView.
This work demonstrates that endothelial EphA4 limits Tie2 activation and curbs leptomeningeal collateral expansion after ischemic stroke. Pharmacological activation of Tie2 by an Ang‐1 mimetic or genetic loss of EphA4 stimulates collateral vessel growth, improves cerebral perfusion, and enhances neurological recovery.
Alexandra M. Kaloss, Caroline de Jager, Kennedie Lyles, Nathalie A. Groot, Jackie Zhu, Yu Lin, Michael Chen, Hehuang Xie, John B. Matson, Michelle H. Theus   +9 more
wiley   +1 more source

Exercise Training‐Induced Adaptations in Mediators of Sustained Endothelium‐Dependent Coronary Artery Relaxation in a Porcine Model of Ischemic Heart Disease

, 2014
Cristine L. Heaps, Juan Carlos Robles, Vandana Sarin, Mildred L. Mattox, Janet L. Parker   +4 more
openalex   +2 more sources

HMGB2 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through MTA2‐Driven Metabolic Reprogramming

Advanced Science, EarlyView.
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou, Ling‐Feng Gu, Yi‐Xi Chen, Peng Jing, Tong‐Tong Yang, Ye He, Yu‐Lin Bao, Xiang‐Zheng Zhang, Chong Du, Si‐Bo Wang, Tian‐Kai Shan, Jia‐Yi Chen, Hao Wang, Qi‐Ming Wang, Li‐Ping Xie, Yang Zhao, Yong Ji, Lian‐Sheng Wang   +17 more
wiley   +1 more source

Urbanization and Coronary Disease [PDF]

BMJ, 1965
openaire   +2 more sources

Intensive lipid lowering with atorvastatin in patients with stable coronary disease.

New England Journal of Medicine, 2005
J. Larosa, S. Grundy, D. Waters, C. Shear, P. Barter, J. Fruchart, A. Gotto, H. Greten, J. Kastelein, J. Shepherd, N. Wenger   +10 more
semanticscholar   +1 more source

FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine

Advanced Science, EarlyView.
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang, Yinghui Xu, Xianpeng Wu, Mo Li, Changchen Xiao, Zaiyang Fu, Yongjian Chen, Qingju Li, Yating Ruan, Jing Zhao, Zhiwei Zhong, Jinghai Chen, Wei Zhu, Jinliang Nan, Cheng Ni, Xinyang Hu   +15 more
wiley   +1 more source