Results 151 to 160 of about 1,254,536 (301)

Rethinking Statin Dosage in Coronary Disease. [PDF]

Pharmacol Res Perspect
Dimmitt SB, Stampfer HG, Kennedy MC, Martin JH.   +3 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Sex Differences in Coronary Disease Health Status Outcomes: the ISCHEMIA Trial. [PDF]

Eur Heart J Qual Care Clin Outcomes
Grodzinsky A, Cho YJ, Jones PG, Shaw L, Merz CNB, Boden W, Stone G, Mark DB, Spertus JA, Maron DJ, Hochman JS, Reynolds HR.   +11 more
europepmc   +1 more source

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

Advanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli, Andrea Pianetti, Elena Mancinelli, Anthea Villano, Matteo Vailati, Paola Lagonegro, Miryam Criado‐Gonzalez, Montserrat Climent, Hansel Comas‐Rojas, Leonardo Elia, Francesco Moccia, Gabriele Tullii, Maria Rosa Antognazza   +12 more
wiley   +1 more source

Surgical Repair of Multiple Coronary Artery Aneurysms With Multivessel Coronary Disease. [PDF]

JACC Case Rep
Zhu X, Wang Y, Zhu L, Zhou Q, Fan F.
europepmc   +1 more source

Metformin Attenuates Myocardial Ischemia–Reperfusion Injury in Rats by Modulating JNK Pathway and Inhibiting PANoptosis Mechanisms

Cardiovascular Therapeutics
Biao Hou, Xuejian Hou, Liyue Zhang, Tingting Liu, Yang Li, Ran Dong   +5 more
doaj   +1 more source

A Nanobody‐LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin, Zhiying Huang, Hai Huang, Yupei Zhang, Yuting Chen, Xi He, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Xiangrong Song   +9 more
wiley   +1 more source

Overall coronary disease burden modifies the prognostic benefit of CTO-PCI: a SYNTAX score-stratified meta-analysis. [PDF]

Eur Heart J Open
Cocco N, Mashayekhi K, Spanò A, Behnes M, Agostoni P, Weilenmann D, Ungureanu C, Colletti G, Boukhris M, Cocco G, Valeria C, Nusca A, Ussia GP, Leibundgut G.   +13 more
europepmc   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

P2Y12 Inhibitor or Aspirin Monotherapy for Chronic Coronary Disease: A Nationwide Cohort Study. [PDF]

Cardiovasc Ther
Baik M, Jeon J, Yoo J, Kim J.
europepmc   +1 more source