Results 131 to 140 of about 822,699 (313)
Advanced Science, EarlyView.Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang +3 more
wiley +1 more source
Trends in coronary heart disease mortality: age groups and populations [PDF]
, 2014 Summary: This report examines how trends in the decline of coronary heart disease (CHD) mortality differ among age groups, and by Aboriginal and Torres Strait Islander status, geographic location and socioeconomic status (SES). All Australians Although
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B lymphocytes and hyperglycemia synergistically exacerbate coronary in-stent restenosis
International Journal of Cardiology. Cardiovascular Risk and PreventionBackground: Lymphocytes are tightly associated with coronary artery disease (CAD). However, there is a lack of clinical evidence that lymphocyte subsets are associated with in-stent restenosis (ISR). The aim of this clinical research was to elucidate the
Duo Yang +9 more
doaj +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy
Advanced Science, EarlyView.Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee +11 more
wiley +1 more source
Coronary artery ectasia : remains a clinical dilemma
, 2010 Coronary artery ectasia (CAE) is defined as localized coronary dilatation that exceeds the diameter of normal adjacent segments or the diameter of the patient's largest coronary vessel by 1.5 times.
Henein, Michael Y, +3 more
core +1 more source
Advanced Science, EarlyView.This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley +1 more source
Socioeconomic position and coronary heart disease in older age: associations and possible pathways
, 2009 Low socioeconomic position is known to be associated with greater coronary heart disease (CHD) risk in most developed countries. However, studies have largely focused on the association between socioeconomic position and CHD in middle-aged populations
Ramsay, S.E.
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Objective: Nonalcoholic fatty liver disease has been connected to coronary artery disease, which is the main cause of mortality. The connection between the degree of nonalcoholic fatty liver disease-induced liver fibrosis and the severity of coronary ...
Emin Murat Akbaş +3 more
core +1 more source
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source