Results 191 to 200 of about 6,097,099 (307)

Robotic-Assisted Aortic Valve Replacement in a Hybrid Approach to Concomitant Aortic Valve and Coronary Disease. [PDF]

JACC Case Rep
Toubat O, Dymond DJ, Scimeca K, Gersak B, Vernick WJ, Conicelli P, Brown CR, Fenning R, Szeto WY, Acker MA, Ibrahim ME.   +10 more
europepmc   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

Whole blood epigenomic and transcriptomic characterization identifies vulnerable molecular subtypes of chronic coronary disease. [PDF]

Nat Commun
Muller M, Cornwell MG, Rajkumar S, Chen Z, Coit D, Drouard G, Sastourne-Haletou P, Yang H, Raitakari O, Lehtimäki T, Hochman J, Maron DJ, Berger JS, Newman JD, Ruggles KV, ISCHEMIA Biorepository Research Group.   +15 more
europepmc   +1 more source

Engineering a Bioelectronic Hybrid Heart with Integrated Sensing and Electrical Modulation

Advanced Science, EarlyView.
A bioelectronic hybrid heart is engineered by integrating iPSC‐derived cardiomyocytes, a decellularized cardiac scaffold, a cell‐laden ECM coating, and a flexible electronic mesh. The embedded electrodes enable real‐time recording of spontaneous electrical activity and localized stimulation, allowing controlled pacing and modulation of activation ...
Itai Cabilly, Hadas Oved, Ron Feiner, Nadav Noor, Moran Yadid, Melanie Flury, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Surgical Repair of Multiple Coronary Artery Aneurysms With Multivessel Coronary Disease. [PDF]

JACC Case Rep
Zhu X, Wang Y, Zhu L, Zhou Q, Fan F.
europepmc   +1 more source

Macrophage GLUD1 is Essential for Redox Balance and Immune Homeostasis in Cardiac Injury

Advanced Science, EarlyView.
Excessive free radical production and dysregulated immune responses are key contributors to myocardial ischemia‐reperfusion (IR) injury. Macrophage GLUD1 activity safeguards against HIF‐1α accumulation and maladaptive responses to IR‐induced ROS production.
Tingting Jin, Chaojie Lai, Qingyan Zhou, Ruilin Wang, Yiping Tong, Wentao Chen, Nikola Rabrenovic, Tingyu Zhang, Xinrong Ren, Chengchen Huang, Jiawen Chen, Ran Li, Luyang Yu, Massimiliano Mazzone, Wenbin Zhang, Guosheng Fu, Min Shang   +16 more
wiley   +1 more source

Differences in coronary disease severity at time of acute coronary syndrome between Middle East and North America. [PDF]

Cardiovasc Diagn Ther
Al Badarin FJ, Edris A, Hashmani S, Kaur M, Shekhar S, Kanwar O, Kapadia S, Tuzcu EM.   +7 more
europepmc   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

Echocardiographic Strain-derived Predictors of Coronary Disease Burden Assessed by SYNTAX Score in Non-ST-elevation Acute Coronary Syndrome. [PDF]

J Cardiovasc Echogr
Horozić D, Durak-Nalbantić A, Hujdur M, Jusić O, Redžepović A, Đokić Vjezović A, Gljiva-Gogić Z, Melezović I, Begić A, Vanis N, Džubur A.   +10 more
europepmc   +1 more source

An Infusible Decellularized Extracellular Matrix Material Binds to Vasculature in Infarcted Myocardium and Induces Pro‐Reparative Gene Expression Following Acute Myocardial Infarction Through Inherent Avidity and Bioactive Signaling

Advanced Science, EarlyView.
To better characterize an infusible extracellular matrix (iECM) material, we applied size‐based fractionation to separate out components into two major fractions. We characterized these fractions to understand how material properties such as composition, morphology, and biochemical properties affect bioactive effects in the context of acute myocardial ...
Michael B. Nguyen, Alexander Chen, Quincy Lyons, Van K. Ninh, Maxwell C. McCabe, Colin Luo, Benjamin D. Bridgelal, Connor Uhre, Julian Cheng, Kate E. Reimold, Selena Cao, Kirk C. Hansen, Kevin R. King, Karen L. Christman   +13 more
wiley   +1 more source