Results 251 to 260 of about 11,009,796 (379)

Loss-of-function mutations in APOC3, triglycerides, and coronary disease.

New England Journal of Medicine, 2014
Jacy R. Crosby, G. Peloso, P. Auer, D. Crosslin, N. Stitziel, L. Lange, Y. Lu, Zheng-Zheng Tang, He Zhang, G. Hindy, Nicholas G. D. Masca, K. Stirrups, S. Kanoni, R. Do, G. Jun, Youna Hu, H. Kang, Chenyi Xue, A. Goel, M. Farrall, S. Duga, P. Merlini, R. Asselta, D. Girelli, O. Olivieri, N. Martinelli, Wu Yin, Dermot Reilly, Elizabeth K. Speliotes, C. Fox, K. Hveem, O. Holmen, M. Nikpay, Deborah N. Farlow, T. Assimes, N. Franceschini, Jennifer G. Robinson, K. North, L. Martin, M. DePristo, N. Gupta, S. A. Escher, J. Jansson, Natalie R. van Zuydam, C. Palmer, N. Wareham, W. Koch, T. Meitinger, A. Peters, W. Lieb, R. Erbel, Inke R. Konig, Jochen Kruppa, F. Degenhardt, O. Gottesman, E. Bottinger, C. O’Donnell, B. Psaty, C. Ballantyne, G. Abecasis, J. Ordovás, O. Melander, H. Watkins, M. Orho-Melander, D. Ardissino, R. Loos, R. McPherson, C. Willer, J. Erdmann, A. Hall, N. Samani, P. Deloukas, H. Schunkert, James G. Wilson, C. Kooperberg, S. Rich, R. Tracy, D. Lin, D. Altshuler, S. Gabriel, D. Nickerson, G. Jarvik, L. Cupples, A. Reiner, E. Boerwinkle, S. Kathiresan   +85 more
semanticscholar   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

The effect of colchicine on coagulation in patients with chronic coronary disease who use vitamin K antagonists. [PDF]

Eur J Clin Pharmacol
Houwen JPA, Lalmohamed A, Zwaan J, Egberts TCG, Duyvendak M, Fiolet ATL, Mosterd A.   +6 more
europepmc   +1 more source

Everolimus-Eluting Stents or Bypass Surgery for Left Main Coronary Artery Disease.

New England Journal of Medicine, 2016
G. Stone, J. Sabik, P. Serruys, C. Simonton, P. Généreux, J. Puskas, D. Kandzari, M. Morice, N. Lembo, W. Brown, D. Taggart, A. Banning, B. Merkely, F. Horkay, P. Boonstra, A. V. van Boven, I. Ungi, G. Bogats, S. Mansour, N. Noiseux, M. Sabaté, J. Pomar, M. Hickey, A. Gershlick, P. Buszman, A. Bochenek, E. Schampaert, P. Pagé, O. Dressler, I. Kosmidou, R. Mehran, S. Pocock, A. Kappetein   +32 more
semanticscholar   +1 more source

In Situ Assembly of Transformable Monopeptide on Activated Neutrophils Attenuates NETs‐Induced Hepatocellular Carcinoma Metastasis by Disrupting NE Nuclear Translocation

Advanced Science, EarlyView.
Activated neutrophils release extracellular traps (NETs) that promote tumor metastasis. FTP‐NPs are develpoed, a peptidic nanomaterial that binds NE on neutrophil membranes, forming NE‐fibril clusters that deactivate NE and prevent NETs formation. This strategy reduces metastasis and enhances the anti‐tumor immune response by targeting NE subcellular ...
Yichi Chen, Yijun Wang, Haitao Shang, Jiayue Qiu, Ruotian Zhang, Yuxiang Xiong, Tong Wang, Fengyi Wang, Anbang Wu, Xin Lin, Bolin Wu, Chen Huang, Wen Cheng, Lu Zhang   +13 more
wiley   +1 more source

An Ounce of Prevention for a Pound of Cure?: Lipid-Lowering Therapy for Premature Coronary Disease. [PDF]

JACC Adv
Khurshid S, Kany S.
europepmc   +1 more source

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia

, 1995
J. Shepherd, S. Cobbe, I. Ford, C. Isles, A. Lorimer, P. Macfarlane, J. Mckillop, C. Packard   +7 more
semanticscholar   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Associations between depression, resilience, and fatigue in patients with multivessel coronary disease: A cross-lag study. [PDF]

Int J Nurs Sci
Sun B, Han J, Tian B, Xu Y, Wang J, Wang J.   +5 more
europepmc   +1 more source

RELATIVE DEPRIVATION BETWEEN NEIGHBOURING WARDS IS PREDICTIVE OF CORONARY HEART DISEASE MORTALITY AFTER ADJUSTMENT FOR ABSOLUTE DEPRIVATION OF WARDS [PDF]

, 2011
Thomas Keegan, Steven Allender, Peter Scarborough, Mike Rayner   +3 more
openalex   +1 more source